AUTHOR=Gaviria Aníbal , Tamayo-Trujillo Rafael , Paz-Cruz Elius , Cadena-Ullauri Santiago , Guevara-Ramírez Patricia , Ruiz-Pozo Viviana A. , Cevallos Francisco , Aguirre-Tello Víctor , Risueño Karla , Yánez Martha Paulina , Cabrera-Andrade Alejandro , Zambrano Ana Karina 

TITLE=Assessment of the COVID-19 pandemic progression in Ecuador through seroprevalence analysis of anti-SARS-CoV-2 IgG/IgM antibodies in blood donors

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=Volume 14 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1373450

DOI=10.3389/fcimb.2024.1373450

ISSN=2235-2988

ABSTRACT=Introduction: Coronavirus Disease 2019 (COVID-19) is a severe respiratory illness caused by the RNA virus SARS-CoV-2. Globally, there have been over 759.4 million cases and 6.74 million deaths, while Ecuador has reported more than 1.06 million cases and 35.9 thousand deaths. To describe the COVID-19 pandemic impact and the vaccinations effectiveness in a low-income country like Ecuador, we aim to assess the seroprevalence of IgG and IgM antibodies against SARS-CoV-2 in a sample from healthy blood donors at the Cruz Roja Ecuatoriana. Methods: The present seroprevalence study used a lateral flow immunoassay (LFIA) to detect anti-SARS-CoV-2 IgG and IgM antibodies in months with the highest confirmed case rates (