AUTHOR=Ren Wenbo , Jin Yuting , Shi Lin , Chen Haizhen , Zhang Zichen , Wang Yifei , Zhai Taiyu , Huang Jing 

TITLE=The necessity and challenges of human papillomavirus testing for men

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1563499

DOI=10.3389/fcimb.2025.1563499

ISSN=2235-2988

ABSTRACT=Beyond its historical association with cervical cancer in women, human papillomavirus (HPV) infection poses a widespread health concern, particularly for men. Recent studies have highlighted the prevalence of HPV-related cancers, including penile and anal cancers, among the male population, making the case for male HPV testing all the more compelling. The potential for cross-infection between sexual partners underscores the need for comprehensive screening strategies. However, challenges still remain, such as the limited availability of testing methods and the absence of uniform medical guidelines, hampering effective HPV detection in men. Addressing these challenges through intensified research efforts and the revision of medical guidelines is crucial to enhancing prevention strategies and unlocking significant public health benefits.