AUTHOR=Chen Guoqing , Cao Jin , Qu Yingli , Tian Wenyan , Shen Peng , Liu Xuan , Luo Qin , Song Qinqin , Wen Qi , Xue Guangyu , Hu Yuting , Shi Qiangqiang , Zhang Lifeng , Zhu Rundong , Song Juan , Han Jun 

TITLE=Epidemiological characteristics of adenovirus in children in Yancheng, China, 2023-2024

JOURNAL=Frontiers in Cellular and Infection Microbiology

VOLUME=Volume 15 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1587257

DOI=10.3389/fcimb.2025.1587257

ISSN=2235-2988

ABSTRACT=ObjectiveTo understand the epidemiology and evolutionary characteristics of human adenovirus (HAdV) infecting children in Yancheng, China, during the winter of 2023-2024.MethodsHAdV-positive throat swab samples were collected from pediatric patients in Yancheng. The Hexon, Penton base, and Fiber genes were amplified and sequenced for typing and phylogenetic analysis of HAdV.Results170 HAdV-positive samples were collected and identified from children with acute respiratory infection (ARI) in Yancheng. A total of 133 samples were successfully amplified and sequenced for Hexon, Penton base, and Fiber genes. Phylogenetic analysis showed that HAdV-B3 was the dominant circulating strain, and two strains of B21, one strain of C1 and one strain of C5 were also identified.ConclusionDuring the winter of 2023-2024, HAdV infecting children in Yancheng was mainly the B3 type.