AUTHOR=Cao Peijun , Chen Li , Xie Shaohua , Hu Bin TITLE=Advances in diagnosis and treatment of lung cancer-associated obstructive pneumonia and lung abscess: synergistic strategies for infection control and antitumor therapy JOURNAL=Frontiers in Cellular and Infection Microbiology VOLUME=Volume 15 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2025.1638997 DOI=10.3389/fcimb.2025.1638997 ISSN=2235-2988 ABSTRACT=Lung cancer-associated obstructive pneumonia and pulmonary abscess represent critical oncologic complications. Effective management hinges on dynamically balancing primary tumor control with secondary infection management. Recent major advances in targeted therapy, immunotherapy, and novel anti-infective technologies have driven a shift towards integrated, multidimensional clinical strategies.This review details diagnostic and therapeutic progress for these conditions, emphasizing the critical balance between controlling severe infections and managing antitumor therapy toxicities, alongside recent advances in nanomedicine for pulmonary infections.