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Viruses continue to present humanity with major challenges, in terms of threats to health and quality of life. In many parts of the world virus infections contribute to high levels of death and disease. Furthermore, the continual appearance of novel variants or cross-species virus transmission represents major global threats for the future. Virus infections can range from being asymptomatic through to being acute infections with extensive viraemia, with the possible accompanying immunological sequelae, through to being long-term persistent and chronic infections, which in many cases can result in the development of cancer.
There is a pressing need, not only to understand more completely how different viruses infect their target cells to induce their various pathologies, but also to determine what steps can be taken to block viruses at different points within their life cycles or during disease progression.
Virus and Host, a Specialty Section within Frontiers in Cellular and Infection Microbiology, provides a platform for studies addressing interactions between viruses and their human hosts. In particular, Virus and Host publishes papers on any virus that causes infection in humans, with an emphasis on those which present pressing health issues. Molecular studies that contribute to our understanding of the molecular basis for infection and for the induction of diverse pathologies are also invited. These can include animal modelling but their relevance to human disease should be included.
An often-unrealised element of the study of viruses is the insights that they can provide into fundamental biological processes. We are therefore particularly interested in studies which are cross-cutting and use human viruses to shed light on processes that are relevant for the understanding of cell biology in general.
Basic descriptive or epidemiological analyses are not within the scope of this section.
Indexed in: PubMed, MEDLINE, PubMed Central, Scopus, Web of Science, Google Scholar, DOAJ, CrossRef, Science Citation Index Expanded
PMCID: all published articles receive a PMCID
Virus and Host welcomes submissions of the following article types: Correction, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Review and Specialty Grand Challenge.
All manuscripts must be submitted directly to the section Virus and Host, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
Articles published in the section Virus and Host will benefit from the Frontiers impact and tiering system after online publication. Authors of published original research with the highest impact, as judged democratically by the readers, will be invited by the Chief Editor to write a Frontiers Focused Review - a tier-climbing article. This is referred to as "democratic tiering". The author selection is based on article impact analytics of original research published in all Frontiers specialty journals and sections. Focused Reviews are centered on the original discovery, place it into a broader context, and aim to address the wider community across all of Cellular and Infection Microbiology.
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