Front. Cell. Neurosci. Frontiers in Cellular Neuroscience Front. Cell. Neurosci. 1662-5102 Frontiers Media S.A. 10.3389/fncel.2021.691978 Cellular Neuroscience Correction Corrigendum: VIP Modulation of Hippocampal Synaptic Plasticity: A Role for VIP Receptors as Therapeutic Targets in Cognitive Decline and Mesial Temporal Lobe Epilepsy Cunha-Reis Diana 1 2 * Caulino-Rocha Ana 1 2 1BioISI - Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal 2Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Lisbon, Portugal

Edited and reviewed by: Lucia Ciranna, University of Catania, Italy

 *Correspondence: Diana Cunha-Reis dcreis@ciencias.ulisboa.pt

This article was submitted to Cellular Neurophysiology, a section of the journal Frontiers in Cellular Neuroscience

 14 05 2021 2021 15 691978 07 04 2021 12 04 2021 Copyright © 2021 Cunha-Reis and Caulino-Rocha. 2021 Cunha-Reis and Caulino-Rocha

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 A Corrigendum on VIP Modulation of Hippocampal Synaptic Plasticity: A Role for VIP Receptors as Therapeutic Targets in Cognitive Decline and Mesial Temporal Lobe Epilepsy by Cunha-Reis, D., and Caulino-Rocha, A. (2020). Front. Cell. Neurosci. 14:153. doi: 10.3389/fncel.2020.00153 VIP synaptic plasticity interneurons hippocampus MTLE cognition VPAC1 receptors

In the original article, there was a mistake in Figure 1 as published. Circuits on the left side of the Figure moved down and stretched and do not represent what is described in the text for VIP O/A interneurons and their targets, OLM cells that should have their cell body in the stratum oriens. The corrected Figure 1 appears below.

Representation of VIP-containing interneurons in the rat hippocampus: layer location and target selectivity. PN, pyramidal neuron (triangle, light blue); Interneurons (circles, pink); VIP-containing interneurons (circles, blue); VIP+-CCK+ BCs: VIP-containing basket cells; VIP+ IS O/A IN: VIP-containing interneuron-selective interneuron targeting the stratum oriens/Alveus and VIP+ IS SR IN: VIP-containing interneuron-selective interneuron targeting the stratum radiatum; OLM IN – Stratum oriens interneuron projecting to the Stratum lacunosum-moleculare; SR IN – Stratum radiatum local interneurons. Str.: stratum.

Additionally, in the original article, there was an error in the identification of type II IS cells (a different nomenclature for a subpopulation (and not all) of VIP+ interneurons projecting to the stratum radiatum).

A correction has been made to section VIP in the Hippocampus, Second Paragraph.

The corrected paragraph is shown below.

Detailed immunohistochemistry studies fully characterized hippocampal VIP+ INs dendritic trees and axon projections (Acsády et al., 1996a,b), allowing the classification of VIP+ INs into two fundamental groups according to their targets: VIP+ basket cells are responsible for somatic inhibition of pyramidal cells, are also immunoreactive for cholecystokinin (VIP+-CCK+ BCs, Figure 1) and do not express parvalbumin, as most BCs in the hippocampus. VIP+ INs that selectively innervate other interneurons (VIP+ IS INs) include two subtypes: (a) interneurons with cell bodies located at the stratum pyramidale (SP) or near and projecting to the stratum Oriens/Alveus border (VIP+ IS O/A INs or type III IS cells, Figure 1), that also express the interneuron marker calretinin and target mostly somatostatin-expressing (SOM+) oriens lacunosum-moleculare (OLM) interneurons innervating the distal dendrites of pyramidal cells at the stratum lacunosum-moleculare (SLM) and (b) VIP+ INs that project their axons to the stratum radiatum (SR, VIP+ IS SR INs, Figure 1), with cell bodies located either at the SR/SLM border (type II IS cells) or at SR/SP and targeting interneurons controlling synaptic transmission to proximal dendrites of pyramidal cells in the SR (Acsády et al., 1996a,b; Klausberger and Somogyi, 2008). In genetically modified VIP-eGFP mice, additional targets of VIP+ IS O/A INs in the O/A, including bistratified cells and oriens–oriens INs, have been described and recently a new VIP expressing interneuron population located at the O/A (VIP+ long-range projecting INs, VIP+ LRP INs) was described targeting INs within the O/A in CA1 but also both INs and pyramidal cells within the subiculum (Francavilla et al., 2018). It is not clear if it is also present in the rat hippocampus.

The authors apologize for these errors and state that they do not change the scientific conclusions of the article in any way. The original article has been updated.

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