AUTHOR=Bari Ahmed , Ali Syed S. , Alanazi Amer M. , Mashwani Muhammad A. , Al-Obaid Abdulrahman M. 

TITLE=Synthesis, Antiviral, and Antimicrobial Evaluation of Benzyl Protected Diversified C-nucleosides

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 6 - 2018

YEAR=2018

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2018.00294

DOI=10.3389/fchem.2018.00294

ISSN=2296-2646

ABSTRACT=Formyl glycals are the versatile synthetic intermediates and can serves as precursor for the synthesis of various C and N-nucleosides. Due to the presence of electron donating and electron withdrawing character on formyl sugars which makes the molecule more susceptible to nucleophilic attack we propose the synthesis of diversified C-nucleosides (3-14) by reaction with N,N dinucleophiles utilizing same strategy. These nucleosides were than tested against viral, bacterial and fungal strains.