AUTHOR=Skibińska Monika , Kaźmierczak Marcin , Milcent Thierry , Cytlak Tomasz , Koroniak Henryk , Crousse Benoit TITLE=Direct Access to Substituted 4-CF3 β-Lactams at the C-3 Position JOURNAL=Frontiers in Chemistry VOLUME=Volume 7 - 2019 YEAR=2019 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2019.00526 DOI=10.3389/fchem.2019.00526 ISSN=2296-2646 ABSTRACT=Mono and disubstituted 4-CF3 β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. Wide range of function such as alcohol, alkyls, aryls, ester, double and triple bonds have been introduced.