AUTHOR=Zhang Yintang , Hao Yuanqiang , Chen Shu , Xu Maotian 

TITLE=Photodynamic Therapy of Cancers With Internal Light Sources: Chemiluminescence, Bioluminescence, and Cerenkov Radiation

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 8 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2020.00770

DOI=10.3389/fchem.2020.00770

ISSN=2296-2646

ABSTRACT=Photodynamic therapy is a promising and minimally invasive modality for the treatment of cancers. The use of self-illuminating system as light source provides an intriguing solution to the light-penetration issues of conventional PDT, which have gained considerable research interest in the past few years. This minireview aims to present an overview of self-illuminating PDT systems by using internal light sources (chemiluminescence, bioluminescence, and Cerenkov radiation) and give a brief discussion on the current challenges and future perspectives.