AUTHOR=Qu Jianbo , Zhang Zhi-Hao , Zhang Haitao , Weng Zhen-Tao , Wang Jian-Yong 

TITLE=Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 8 - 2020

YEAR=2021

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2020.602125

DOI=10.3389/fchem.2020.602125

ISSN=2296-2646

ABSTRACT=Diethyl malonate based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity and low cytotoxicity. This turn-on probe NE-N2H4 can be operated to detect hydrazine in the living HeLa cells. Especially, after soaking in probe solution, the TLC plate could detect the vapor of hydrazine. Therefore, the probe NE-N2H4 could be used to monitor hydrazine in biosamples and environmental problem.