AUTHOR=Liu Weiping , Zhou Yu , Xu Xianzhen 

TITLE=Study on vapor–liquid equilibrium and microscopic properties of DL-proline, L-glutamic acid, and L-serine aqueous solutions

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.1005291

DOI=10.3389/fchem.2022.1005291

ISSN=2296-2646

ABSTRACT=The vapor-liquid equilibrium (VLE) of amino acids is essential in chemical production, such as purification, isolation or crystallization of amino acid intermediates. In this work, VLE of DL-Proline, L-glutamic acid, and L-Serine aqueous solutions were measured at pressures ranging from 4.82 kPa to 102.58 kPa. The developed model was successfully applied to correlate experimental data with temperatures in the range of 298.15 K and 382.75 K. Model parameters (h,  ,  ,  and   ) were given. Moreover, the amino acid aqueous solution was investigated by Fourier transform infrared spectroscopy (FTIR). By analyzing infrared spectra, the strength of intermolecular interactions was obtained, the structure-activity relationship between the microscopic interactions and the VLE was established.