AUTHOR=Abedini Ali , Rostami Mojtaba , Banafshe Hamid Reza , Rahimi-Nasrabadi Mehdi , SobhaniNasab Ali , Ganjali Mohammad Reza TITLE=Utility of Biogenic Iron and Its Bimetallic Nanocomposites for Biomedical Applications: A Review JOURNAL=Frontiers in Chemistry VOLUME=Volume 10 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.893793 DOI=10.3389/fchem.2022.893793 ISSN=2296-2646 ABSTRACT=Nanotechnology mainly deals with the production and application of compounds with dimensions in nanoscale. Given their dimensions, these materials have considerable surface/volume ratios and hence specific characteristics. Nowadays, environmentally friendly procedures are being proposed for fabrication of Fe nanoparticles, because large amount of poisonous chemical and unfavorable condition are needed to prepare them. This work includes an inclusive overview on the economical and green procedures for the preparation of such nanoparticles (flower, fruits, tea, carbohydrates and leaves). Pure and bimetallic iron nanoparticles for instance, offers a high bandwidth and excitation binding energy, and are applicable in different areas ranging from antibacterial, anticancer, bio-imaging agents to drug delivery systems. Preparation of nano-sized particles, such as those of Fe requires the application of high quantities of toxic materials and harsh conditions, and naturally, there is a tendency to develop more facile and even green pathways[1-3]. This text tends to provide an overview on the reports describing green and biological methods for the synthesis of Fe nanoparticles. The present review mainly highlights of selenium nanoparticles in the biomedical domain. Specifically, this review will present detailed information on the drug delivery, bioimaging, antibacterial, anti-cancer activity. It will also focus on procedures for their green methodsynthesis and properties that make them potential candidates for applications in various application. Finally, we provide a detailed future outlook.