AUTHOR=Du Yutong , Zhang Xinyi , Liu Ping , Yu Deng-Guang , Ge Ruiliang 

TITLE=Electrospun nanofiber-based glucose sensors for glucose detection

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.944428

DOI=10.3389/fchem.2022.944428

ISSN=2296-2646

ABSTRACT=Diabetes is a chronic, systemic metabolic disease, which leading to multiple complications, even death, while the number of people with diabetes worldwide is increasing year by year. Sensor plays an important role in the development of biomedical devices. The development of efficient, stable and inexpensive glucose sensors for continuous monitoring of blood glucose levels has received widespread attention to provide reliable data for diabetes prevention and diagnosis. Electrospun nanofibers as new kinds of functional nanocomposites show incredible capabilities for high-level biosensing. This article reviews the glucose sensors based on electrospun nanofibers. The principles of the glucose sensor, the types of glucose measurement and the glucose detection methods are briefly concluded firstly. Later, the principle of electrospinning and processes, with applications and advantages in glucose sensors are introduced. This article provides a comprehensive summary of the applications and advantages of polymer and nanomaterials in electrospun nanofibers-based glucose sensors. The relevant applications and comparisons of enzymatic and non-enzymatic nanofibers-based glucose sensors are discussed in detail. The main advantages and disadvantages of glucose sensors based on electrospun nanofibers are evaluated, and solutions are attempted to be proposed. Potential commercial development and improved methods of glucose sensors based on electrospinning nanofibers are discussed.