AUTHOR=Yu Jun-Jie , Wei Wen-Ke , Zhang Yu , Cox Russell J. , He Juan , Liu Ji-Kai , Feng Tao 

TITLE=Terpenoids from Kiwi endophytic fungus Bipolaris sp. and their antibacterial activity against Pseudomonas syringae pv. actinidiae

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.990734

DOI=10.3389/fchem.2022.990734

ISSN=2296-2646

ABSTRACT=A chemical investigation on the kiwi endophytic fungus Bipolaris sp. resulted in the isolation of eight new terpenoids (1–8) and five known analogues (9–13). Compounds 1–5 are novel sativene sesquiterpenoids containing three additional skeletal carbons, while compounds 4 and 5 are rare dimers. Compounds 6–8 and 13 are sesterterpenoids that have been identified from this species for the first time. Compounds 4 and 5 showed antibacterial activity against kiwifruit canker pathogen Pseudomonas syringae pv. actinidiae (Psa) with MIC values of 32 and 64 μg/mL, respectively.