AUTHOR=Qu Huan , Guo Zhen , Ma Li , Zhang Xiu , Ma Haijun , Chen Yang 

TITLE=Antifungal effects and active compounds of the leaf of Allium mongolicum Regel

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 10 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.993893

DOI=10.3389/fchem.2022.993893

ISSN=2296-2646

ABSTRACT=<p>Taking plant metabolites as material to develop new biological fungicides is still an important mission for pesticide development, and the preliminary study confirmed that <italic>Allium mongolicum</italic> showed a certain inhibitory effect on plant pathogens. In this study, the antifungal activity of extracts of <italic>A. mongolicum</italic> was studied and the compounds were isolated, purified, and identified by HPLC, NMR, and ESI-MS. The methanol extract of <italic>A. mongolicum</italic> exhibited certain inhibitory activity against almost all nine tested pathogens at concentration of 0.5 mg/ml. Sixteen compounds were isolated and purified from the extract, which were identified as nine flavonoids, six phenolic acids, and an amino acid. Among them, cinnamic acid derivatives <bold>1</bold>, <bold>2</bold>, and <bold>3</bold> and flavonoids <bold>7</bold>, <bold>8</bold>, <bold>9</bold>, and <bold>13</bold> were separated in <italic>A. mongolicum</italic> for the first time.</p>