AUTHOR=Zhang Sai , Chen Daixiang , Wang Jia-Yin , Yan Shenghu , Li Guigen 

TITLE=Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission

JOURNAL=Frontiers in Chemistry

VOLUME=Volume 11 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2023.1259609

DOI=10.3389/fchem.2023.1259609

ISSN=2296-2646

ABSTRACT=The design and synthesis of a type of [1+4+2] four-layer framework have been conducted by taking advantage of Suzuki-Miyaura cross coupling and group-assisted purification (GAP) chemistry. The optimized coupling of double-layer diboronic esters with 1-bromo-naphth-2-yl phosphine oxides resulted in a series of multilayer folding targets showing a broad scope of substrates and moderate to excellent yields. The final products were purified by GAP chemistry/technology simply by washing crude products with 95% EtOH without the use of chromatography and recrystallization. The structures were fully characterized and assigned by performing X-ray crystallographic analysis. UVvis, photoluminescence (PL) and aggregation-induced emission (AIE) were studied for the resulting multilayer folding products.