AUTHOR=Wang Haocheng , Sun Jingxue , Zhang Xiaona , Zhou Yingjie , Zhang Yaguang , Ni Yanan , Wang Minnan , Wu Yanmeizhi , Sun Lulu , Zhao Xiaoyu , Qiao Hong TITLE=Micro-nano robots for treatment of eye diseases JOURNAL=Frontiers in Chemistry VOLUME=Volume 13 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2025.1553461 DOI=10.3389/fchem.2025.1553461 ISSN=2296-2646 ABSTRACT=In recent years, micro-nano robots have found extensive applications in the field of medicine. Among these, micro-nano robots demonstrate significant potential for the treatment of eye diseases. Micro-nano robots can penetrate eye tissue barriers to directly target the posterior segment of the eye for precise drug delivery, enabling non-invasive or minimally invasive treatment. This review explores the primary fabrication methods and propulsion mechanisms of various micro-nano robots, and their applications in treating various eye conditions, offering inspiration and guidance for advancing the use of micro-nanorobots in ophthalmic therapies.