AUTHOR=Brasseur Guy , Stammer Detlef , Friedlingstein Pierre , Hegerl Gabriele , Shaw Tiffany , Trenberth Kevin , Richter Jadwiga , Vera Carolina , Berger André , Cleugh Helen , Easterbrook Steve , Edwards Paul , Jacob Daniela , Mann Michael , Masson-Delmotte Valérie , Schmidt Gavin , Scholes Mary , Stocker Thomas , Visbeck Martin , Wu Guoxiong TITLE=Climate science for 2050 JOURNAL=Frontiers in Climate VOLUME=Volume 7 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/climate/articles/10.3389/fclim.2025.1554685 DOI=10.3389/fclim.2025.1554685 ISSN=2624-9553 ABSTRACT=Knowledge of the functioning of the climate system, including the physical, dynamical and biogeochemical feedback processes expected to occur in response to anthropogenic climate forcing, has increased substantially over recent decades. Today, climate science is at a crossroads, with new and urgent demands arising from the needs of society to deal with future climate change, and the need for the climate science community to refine its strategic goals to meet these demands rapidly. All possible—but currently unknown—worlds in 2050, with a larger global population, unprecedented climate conditions with higher temperatures, more frequent extreme weather events, sea level rise, disrupted ecosystems, changes in habitability and increased climate-induced displacement and migration, and the emergence of new geopolitical tensions, will require limiting society’s vulnerability both through mitigation measures to minimize further warming and through the implementation of innovative adaptation initiatives. The development of a skillful climate information system, based on the most advanced Earth system science, will be required to inform decision-makers and the public around the world about the local and remote impacts of climate change, and guide them in optimizing their adaptation and mitigation agendas. This information will also help manage renewable resources in a warmer world and strengthen resilience to the expected interconnected impacts of climate change. In this paper, we summarize the major advances needed to understand the multiscale dynamics of the Earth system. We highlight the need to develop an integrated information system accessible to decision-makers and citizens in all parts of the world, and present some of the key scientific questions that need to be addressed to inform decisions on mitigation and adaptation. Finally, we speculate about the values and ethics of climate science and the nature of climate research in a world that will be increasingly affected by global warming in a geopolitical context very different from that of recent decades.