AUTHOR=Yang Yong , Li Feng , Luo Jing , Qin Xiaolin , Huang Dong 

TITLE=Epileptic focus localization using transfer learning on multi-modal EEG

JOURNAL=Frontiers in Computational Neuroscience

VOLUME=Volume 17 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2023.1294770

DOI=10.3389/fncom.2023.1294770

ISSN=1662-5188

ABSTRACT=The standard treatments for epilepsy are drug therapy and surgical resection. However, around 1/3 of patients with intractable epilepsy are drug-resistant, requiring surgical resection of the epileptic focus. To address the issue of drug-resistant epileptic focus localization, we have proposed a transfer learning method on multi-modal EEG (iEEG and sEEG). A 10-fold cross-validation approach was applied to validate the performance of the pre-trained model on the Bern-Barcelona and Bonn datasets, achieving accuracy rates of 94.50% and 97.50% respectively. The experimental results have demonstrated that the pre-trained model outperforms the competitive state-of-the-art baselines in terms of accuracy, sensitivity, and negative predictive value. Furthermore, we fine-tuned our pretrained model using the epilepsy dataset from Chongqing Medical University and tested it using the leave-one-out cross-validation method, obtaining an impressive average accuracy of 90.15%. Therefore, the superior performance of the model has demonstrated that the proposed method is highly effective for localizing epileptic focus and can aid physicians in clinical localization diagnosis.