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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Comput. Sci.</journal-id>
<journal-title>Frontiers in Computer Science</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Comput. Sci.</abbrev-journal-title>
<issn pub-type="epub">2624-9898</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fcomp.2023.1152592</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Computer Science</subject>
<subj-group>
<subject>Review</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>The odyssey to next-generation computers: <italic>cognitive computers</italic> (&#x003BA;<italic>C</italic>) inspired by the brain and powered by intelligent mathematics</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name><surname>Wang</surname> <given-names>Yingxu</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1343143/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Widrow</surname> <given-names>Bernard</given-names></name>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Hoare</surname> <given-names>C. A. R.</given-names></name>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Pedrycz</surname> <given-names>Witold</given-names></name>
<xref ref-type="aff" rid="aff4"><sup>4</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1727217/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Berwick</surname> <given-names>Robert C.</given-names></name>
<xref ref-type="aff" rid="aff5"><sup>5</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/33263/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Plataniotis</surname> <given-names>Konstantinos N.</given-names></name>
<xref ref-type="aff" rid="aff6"><sup>6</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1498762/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Rudas</surname> <given-names>Imre J.</given-names></name>
<xref ref-type="aff" rid="aff7"><sup>7</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/205851/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Lu</surname> <given-names>Jianhua</given-names></name>
<xref ref-type="aff" rid="aff8"><sup>8</sup></xref>
</contrib>
<contrib contrib-type="author">
<name><surname>Kacprzyk</surname> <given-names>Janusz</given-names></name>
<xref ref-type="aff" rid="aff9"><sup>9</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/1125630/overview"/>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Department of Electrical and Software Engineering/Hotchkiss Brain Institute, University of Calgary</institution>, <addr-line>Calgary, AB</addr-line>, <country>Canada</country></aff>
<aff id="aff2"><sup>2</sup><institution>Department of Electrical Engineering, Stanford University</institution>, <addr-line>Stanford, CA</addr-line>, <country>United States</country></aff>
<aff id="aff3"><sup>3</sup><institution>Department of Computer Science, University of Oxford</institution>, <addr-line>Oxford</addr-line>, <country>United Kingdom</country></aff>
<aff id="aff4"><sup>4</sup><institution>Department of Electrical and Computer Engineering, University of Alberta</institution>, <addr-line>Edmonton, AB</addr-line>, <country>Canada</country></aff>
<aff id="aff5"><sup>5</sup><institution>Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology</institution>, <addr-line>Cambridge, MA</addr-line>, <country>United States</country></aff>
<aff id="aff6"><sup>6</sup><institution>Department of Electrical and Computer Engineering, University of Toronto</institution>, <addr-line>Toronto, ON</addr-line>, <country>Canada</country></aff>
<aff id="aff7"><sup>7</sup><institution>Research and Innovation Center, &#x000D3;buda University</institution>, <addr-line>Budapest</addr-line>, <country>Hungary</country></aff>
<aff id="aff8"><sup>8</sup><institution>Department of Electronic Engineering, Tsinghua University</institution>, <addr-line>Beijing</addr-line>, <country>China</country></aff>
<aff id="aff9"><sup>9</sup><institution>Systems Research Institute, Polish Academy of Sciences</institution>, <addr-line>Warsaw</addr-line>, <country>Poland</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Kaleem Siddiqi, McGill University, Canada</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Boris Kovalerchuk, Central Washington University, United States; Jun Peng, Chongqing University of Science and Technology, China; George Baciu, Hong Kong Polytechnic University, Hong Kong SAR, China</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Yingxu Wang <email>yingxu&#x00040;ucalgary.ca</email></corresp>
</author-notes>
<pub-date pub-type="epub">
<day>19</day>
<month>05</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="collection">
<year>2023</year>
</pub-date>
<volume>5</volume>
<elocation-id>1152592</elocation-id>
<history>
<date date-type="received">
<day>28</day>
<month>01</month>
<year>2023</year>
</date>
<date date-type="accepted">
<day>31</day>
<month>03</month>
<year>2023</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2023 Wang, Widrow, Hoare, Pedrycz, Berwick, Plataniotis, Rudas, Lu and Kacprzyk.</copyright-statement>
<copyright-year>2023</copyright-year>
<copyright-holder>Wang, Widrow, Hoare, Pedrycz, Berwick, Plataniotis, Rudas, Lu and Kacprzyk</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license> </permissions>
<abstract>
<p><italic>Cognitive computers</italic> (&#x003BA;<italic>C</italic>) are intelligent processors advanced from data and information processing to autonomous knowledge learning and intelligence generation. This work presents a retrospective and prospective review of the odyssey toward &#x003BA;<italic>C</italic> empowered by transdisciplinary basic research and engineering advances. A wide range of fundamental theories and innovative technologies for &#x003BA;<italic>C</italic> is explored, and a set of underpinning <italic>intelligent mathematics</italic> (IM) is created. The architectures of &#x003BA;<italic>C</italic> for cognitive computing and <italic>Autonomous Intelligence Generation</italic> (AIG) are designed as a brain-inspired cognitive engine. Applications of &#x003BA;<italic>C</italic> in <italic>autonomous AI</italic> (AAI) are demonstrated by pilot projects. This work reveals that AIG will no longer be a privilege restricted only to humans via the odyssey to &#x003BA;<italic>C</italic> toward training-free and self-inferencing computers.</p></abstract>
<kwd-group>
<kwd><italic>cognitive computers</italic> (&#x003BA;<italic>C</italic>)</kwd>
<kwd>intelligent science</kwd>
<kwd>knowledge science</kwd>
<kwd><italic>intelligent mathematics</italic></kwd>
<kwd>brain-inspired systems (BIS)</kwd>
<kwd><italic>autonomous intelligence generation</italic> (AIG)</kwd>
<kwd><italic>autonomous AI</italic> (AAI)</kwd>
<kwd>experiments</kwd>
</kwd-group>
<counts>
<fig-count count="11"/>
<table-count count="0"/>
<equation-count count="17"/>
<ref-count count="85"/>
<page-count count="18"/>
<word-count count="10641"/>
</counts>
<custom-meta-wrap>
<custom-meta>
<meta-name>section-at-acceptance</meta-name>
<meta-value>Software</meta-value>
</custom-meta>
</custom-meta-wrap>
</article-meta>
</front>
<body>
<sec id="s1">
<title>1. Introduction</title>
<p>A spectrum of basic research and disruptive technologies [Newton, <xref ref-type="bibr" rid="B17">1729</xref>; Boole, <xref ref-type="bibr" rid="B6">1854</xref>; Russell, <xref ref-type="bibr" rid="B21">1903</xref>; Hoare, <xref ref-type="bibr" rid="B9">1969</xref>; Kline, <xref ref-type="bibr" rid="B14">1972</xref>; <xref ref-type="bibr" rid="B1">Aristotle (384 BC&#x02212;322 BC</xref>), <xref ref-type="bibr" rid="B1">1989</xref>; Zadeh, <xref ref-type="bibr" rid="B85">1997</xref>; Wilson and Frank, <xref ref-type="bibr" rid="B84">1999</xref>; Bender, <xref ref-type="bibr" rid="B3">2000</xref>; Timothy, <xref ref-type="bibr" rid="B25">2008</xref>; Widrow, <xref ref-type="bibr" rid="B82">2022</xref>] has triggered the emergence of <italic>Cognitive Computers</italic> (&#x003BA;<italic>C</italic>) (Wang, <xref ref-type="bibr" rid="B47">2012e</xref>), which paved a way to <italic>autonomous artificial intelligence</italic> (AAI) (Wang, <xref ref-type="bibr" rid="B66">2022g</xref>) and machine intelligence generation (Birattari and Kacprzyk, <xref ref-type="bibr" rid="B5">2001</xref>; Kacprzyk and Yager, <xref ref-type="bibr" rid="B13">2001</xref>; Pedrycz and Gomide, <xref ref-type="bibr" rid="B18">2007</xref>; Rudas and Fodor, <xref ref-type="bibr" rid="B20">2008</xref>; Siddiqi and Pizer, <xref ref-type="bibr" rid="B24">2008</xref>; Wang et al., <xref ref-type="bibr" rid="B72">2009</xref>, <xref ref-type="bibr" rid="B80">2016b</xref>, <xref ref-type="bibr" rid="B81">2017</xref>, <xref ref-type="bibr" rid="B73">2018</xref>; Cios et al., <xref ref-type="bibr" rid="B7">2012</xref>; Berwick et al., <xref ref-type="bibr" rid="B4">2013</xref>; Wang, <xref ref-type="bibr" rid="B51">2016a</xref>, <xref ref-type="bibr" rid="B56">2021a</xref>; Plataniotis, <xref ref-type="bibr" rid="B19">2022</xref>; Huang et al., <xref ref-type="bibr" rid="B12">2023</xref>). The odyssey to &#x003BA;<italic>C</italic> is inspired by the brain (Siddiqi and Pizer, <xref ref-type="bibr" rid="B24">2008</xref>; Wang et al., <xref ref-type="bibr" rid="B72">2009</xref>, <xref ref-type="bibr" rid="B80">2016b</xref>, <xref ref-type="bibr" rid="B73">2018</xref>; Wang, <xref ref-type="bibr" rid="B56">2021a</xref>) and enabled by <italic>intelligent mathematics</italic> (IM) (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B43">2012a</xref>,<xref ref-type="bibr" rid="B44">b</xref>, <xref ref-type="bibr" rid="B55">2020</xref>, <xref ref-type="bibr" rid="B62">2022c</xref>, <xref ref-type="bibr" rid="B69">2023</xref>). It is initiated by the fundamental queries on what classic AI cannot do and how &#x003BA;<italic>C</italic> will enable AAI (Birattari and Kacprzyk, <xref ref-type="bibr" rid="B5">2001</xref>; Kacprzyk and Yager, <xref ref-type="bibr" rid="B13">2001</xref>; Pedrycz and Gomide, <xref ref-type="bibr" rid="B18">2007</xref>; Rudas and Fodor, <xref ref-type="bibr" rid="B20">2008</xref>; Siddiqi and Pizer, <xref ref-type="bibr" rid="B24">2008</xref>; Wang et al., <xref ref-type="bibr" rid="B72">2009</xref>, <xref ref-type="bibr" rid="B80">2016b</xref>, <xref ref-type="bibr" rid="B81">2017</xref>, <xref ref-type="bibr" rid="B73">2018</xref>; Cios et al., <xref ref-type="bibr" rid="B7">2012</xref>; Wang, <xref ref-type="bibr" rid="B43">2012a</xref>, <xref ref-type="bibr" rid="B51">2016a</xref>, <xref ref-type="bibr" rid="B55">2020</xref>, <xref ref-type="bibr" rid="B56">2021a</xref>, <xref ref-type="bibr" rid="B62">2022c</xref>,<xref ref-type="bibr" rid="B66">g</xref>; Berwick et al., <xref ref-type="bibr" rid="B4">2013</xref>; Plataniotis, <xref ref-type="bibr" rid="B19">2022</xref>; Huang et al., <xref ref-type="bibr" rid="B12">2023</xref>) theories and technologies beyond classical <italic>pretrained AI</italic> based on data convolution and <italic>preprogrammed computing</italic> underpinned by pre-deterministic run-time behaviors.</p>
<p>Although it is well recognized that <italic>data, information, knowledge</italic>, and <italic>intelligence</italic> are the fundamental cognitive objects in the brain (Boole, <xref ref-type="bibr" rid="B6">1854</xref>; Wilson and Frank, <xref ref-type="bibr" rid="B84">1999</xref>; Wang et al., <xref ref-type="bibr" rid="B72">2009</xref>) and AAI systems, as illustrated in <xref ref-type="fig" rid="F1">Figure 1</xref>, there is a lack of formal studies on their transition and aggregation. The contemporary and traditional perceptions, metaphors, and relationships of the basic cognitive objects in the brain and intelligent systems are analyzed in this section. The taxonomy of cognitive objects in the brain may be formally classified into four forms according to the hierarchical <italic>cognitive framework of the brain</italic> (CFB) (Wang, <xref ref-type="bibr" rid="B31">2003</xref>, <xref ref-type="bibr" rid="B61">2022b</xref>; Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>, <xref ref-type="bibr" rid="B71">2021a</xref>).</p>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>Cognitive framework of the brain (CFB).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0001.tif"/>
</fig>
<p><bold>Definition 1</bold>. The <italic>hierarchy of cognitive objects</italic> (<italic>HCO</italic>) represented in the brain is a four-tuple encompassing the categories of <italic>data</italic> (&#x1D53B;), <italic>information</italic> (<inline-formula><mml:math id="M102"><mml:mi mathvariant='double-struck'>I</mml:mi></mml:math></inline-formula>), <italic>knowledge</italic> (<inline-formula><mml:math id="M103"><mml:mi mathvariant='double-struck'>K</mml:mi></mml:math></inline-formula>), and <italic>intelligence</italic> (<inline-formula><mml:math id="M1"><mml:mover accent="true"><mml:mrow><mml:mi mathvariant='double-struck'>I</mml:mi></mml:mrow><mml:mo>&#x022C5;</mml:mo></mml:mover></mml:math></inline-formula>) from the bottom up with increasing intelligence power as well as complexity:</p>
<disp-formula id="E1"><label>(1)</label><mml:math id="M2"><mml:mtable columnalign='left'><mml:mtr><mml:mtd><mml:mi>H</mml:mi><mml:mi>C</mml:mi><mml:mi>O</mml:mi><mml:mo>&#x02259;</mml:mo><mml:mo stretchy='false'>(</mml:mo><mml:mi mathvariant='double-struck'>D</mml:mi><mml:mo>,</mml:mo><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mo>,</mml:mo><mml:mi mathvariant='double-struck'>K</mml:mi><mml:mo>,</mml:mo><mml:mover><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mo>.</mml:mo></mml:mover><mml:mo stretchy='false'>)</mml:mo></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext>&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;=</mml:mtext><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable columnalign='left'><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mi mathvariant='double-struck'>D</mml:mi><mml:mo>=</mml:mo><mml:msub><mml:mi>f</mml:mi><mml:mi>d</mml:mi></mml:msub><mml:mo>:</mml:mo><mml:mi>O</mml:mi><mml:mo>&#x02192;</mml:mo><mml:mi>Q</mml:mi><mml:mtext>&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>p</mml:mi><mml:mi>y</mml:mi><mml:mi>u</mml:mi><mml:mo stretchy='false'>]</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mo>=</mml:mo><mml:msub><mml:mi>f</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo>:</mml:mo><mml:mi>D</mml:mi><mml:mo>&#x02192;</mml:mo><mml:mi>S</mml:mi><mml:mtext>&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>t</mml:mi><mml:mo stretchy='false'>]</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mi mathvariant='double-struck'>K</mml:mi><mml:mo>=</mml:mo><mml:msub><mml:mi>f</mml:mi><mml:mi>k</mml:mi></mml:msub><mml:mo>:</mml:mo><mml:mi>I</mml:mi><mml:mo>&#x02192;</mml:mo><mml:mi>C</mml:mi><mml:mtext>&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>r</mml:mi><mml:mo stretchy='false'>]</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mover><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mo>.</mml:mo></mml:mover><mml:mo>=</mml:mo><mml:msub><mml:mi>f</mml:mi><mml:mover accent='true'><mml:mi>i</mml:mi><mml:mo>&#x002D9;</mml:mo></mml:mover></mml:msub><mml:mo>:</mml:mo><mml:mi>I</mml:mi><mml:mo>&#x02192;</mml:mo><mml:mi>B</mml:mi><mml:mtext>&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>p</mml:mi><mml:mo stretchy='false'>]</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where the symbols denote sets of <italic>objects</italic> (<italic>O</italic>), <italic>quantities</italic> (<italic>Q</italic>), <italic>signals/events</italic> (<italic>S</italic>), <italic>concepts</italic> (<italic>C</italic>), and <italic>behaviors</italic> (<italic>B</italic>), respectively.</p>
<p>It is noteworthy in Equation (1) that the essences of <italic>HCO</italic> are embodied by distinguished properties quantified by different cognitive units. The unit of data is a scalar quantity implied by its <italic>physical unit</italic> (<italic>pyu</italic>) of a certain corresponding qualification scale. <italic>Bit</italic> (<inline-formula><mml:math id="M104"><mml:mi mathvariant='double-struck'>B</mml:mi></mml:math></inline-formula>) for information is a scalar <italic>binary digit</italic> introduced by Shannon (<xref ref-type="bibr" rid="B23">1948</xref>). <italic>Bir</italic> for knowledge is a <italic>binary relation</italic> discovered by Wang in 2018 (Wang, <xref ref-type="bibr" rid="B53">2016c</xref>). It leads to the highest level of cognitive units, <italic>bip</italic>, which denotes a <italic>binary process</italic> of knowledge-based behaviors triggered by the information of an event (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>).</p>
<p><bold>Example 1</bold>. The inductive and hierarchical aggregation from data, information, and knowledge to intelligence in the brain may be illustrated by the cognitive model of an arbitrary AND-gate as follows (Wang, <xref ref-type="bibr" rid="B54">2018</xref>):</p>
<p>Given an AND-gate with input size |<italic>I</italic>| = <italic>n</italic> = 10,000 pins and one output |<italic>O</italic>| = 1, its cognitive complexities at different levels according to <italic>HCO</italic> are extremely different:</p>
<list list-type="simple">
<list-item><p>1) Data: 2<sup>10,000</sup> bits &#x021D0; super big!</p></list-item>
<list-item><p>2) Information: 10,000 bits</p></list-item>
<list-item><p>3) Knowledge: 2 rules <inline-formula><mml:math id="M100"><mml:mrow><mml:mo>&#x021D2;</mml:mo><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable><mml:mtr><mml:mtd><mml:mrow><mml:mi>O</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:mtd><mml:mtd><mml:mrow><mml:mi>i</mml:mi><mml:mi>f</mml:mi><mml:mi>f</mml:mi><mml:munderover><mml:mtext>R</mml:mtext><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow><mml:mi>n</mml:mi></mml:munderover><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mi>I</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo>&#x02261;</mml:mo><mml:mn>1</mml:mn><mml:mtext>&#x000A0;&#x000A0;</mml:mtext></mml:mrow></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mrow><mml:mi>O</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn><mml:mo>,</mml:mo></mml:mrow></mml:mtd><mml:mtd><mml:mrow><mml:mi>o</mml:mi><mml:mi>t</mml:mi><mml:mi>h</mml:mi><mml:mi>e</mml:mi><mml:mi>r</mml:mi><mml:mi>w</mml:mi><mml:mi>i</mml:mi><mml:mi>s</mml:mi><mml:mi>e</mml:mi></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mrow></mml:math></inline-formula></p></list-item>
<list-item><p>4) Intelligence: &#x02200; <italic>n</italic>, <italic>O</italic> = <italic>f(n) = AND(n)</italic></p>
<p>// It becomes a generic logical function learnt by <italic>&#x003BA;</italic> C independent from <italic>n</italic></p></list-item>
</list>
<p>The example reveals if a machine tries to learn how an AND-gate behaves at the data level, it always faces an extremely complex problem that easily becomes intractable. However, human brains may quickly reduce the problem to a general and simple logic function at the intelligence level. This is the fundamental difference between current data-training-based machine learning technologies and the natural intelligence of the brain underpinning &#x003BA;<italic>C</italic>.</p>
<p>The odyssey of computing theories and technologies from Babbage (<xref ref-type="bibr" rid="B2">1822</xref>)&#x00027;s mechanical machines, Turing (<xref ref-type="bibr" rid="B26">1950</xref>)&#x00027;s extended <italic>finite state machines</italic> (FSM), von Neumann (<xref ref-type="bibr" rid="B29">1946</xref>)&#x00027;s stored-program-controlled computers, to regressive and convolutional neural-networks-driven AI systems (McCarthy et al., <xref ref-type="bibr" rid="B16">1955</xref>), has led to the emergence of &#x003BA;<italic>C</italic> for autonomous intelligence generation (Wang, <xref ref-type="bibr" rid="B47">2012e</xref>). &#x003BA;<italic>C</italic> manipulates cognitive entities as <italic>hyperstructures</italic> <italic>(&#x0210D;</italic>) (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B39">2009a</xref>) beyond classic discrete objects in a set of <italic>real numbers</italic> <italic>(&#x0211D;</italic>). &#x0210D; reveals the latest discovery on the essence of knowledge and intelligence where the target objects have been out of the domain of <italic>B</italic> and &#x0211D;, which are challenging the processing power of traditional mathematical means and computing models used for manipulating data and information.</p>
<p><bold>Definition 2</bold>. A <italic>cognitive computer</italic> (&#x003BA;<italic>C</italic>) is a fully intelligent computer, aggregated from data and information processing, to provide a cognitive engine for empirical knowledge acquisition and autonomous intelligence generation driven by IM.</p>
<p>&#x003BA;<italic>C</italic> is a disruptive technology for AAI that implements brain-inspired computers powered by <italic>non-preprogramed</italic> computing and <italic>non-pretrained</italic> AI based on the latest breakthroughs in cognitive computing theories (Wang, <xref ref-type="bibr" rid="B40">2009b</xref>, <xref ref-type="bibr" rid="B42">2011</xref>, <xref ref-type="bibr" rid="B45">2012c</xref>), and <italic>intelligent mathematics</italic> (Wang, <xref ref-type="bibr" rid="B57">2021b</xref>). The philosophy of &#x003BA;<italic>C</italic> is underpinned by that it is impossible to either preprogram all future behaviors pending by unpredicted runtime demands or pretrain all application scenarios in real-time in the infinite discourse of (<italic>H</italic>).</p>
<p>This study presents a retrospective and prospective review of the odyssey toward contemporary &#x003BA;<italic>C</italic> driven by transdisciplinary basic research and technology advances. A comprehensive scope of philosophical and theoretical perspectives on &#x003BA;<italic>C</italic> as well as transdisciplinary theories and IM for &#x003BA;<italic>C</italic> will be explored in Section 2. The architecture and functions of &#x003BA;<italic>C</italic> will be modeled in Section 3 as brain-inspired autonomous systems. Applications of &#x003BA;<italic>C</italic> will be demonstrated in Section 4 via experiments on machine knowledge learning for enabling autonomous machine intelligence generation.</p></sec>
<sec id="s2">
<title>2. Transdisciplinary discoveries on the theoretical foundations of <italic>&#x003BA;C</italic></title>
<p>The <italic>universe of discourse</italic> of contemporary sciences is a dual of natural and abstract sciences as shown in <xref ref-type="fig" rid="F2">Figure 2</xref>. In recent decades, a number of scientific disciplines have emerged as abstract sciences such as <italic>data, information, knowledge</italic>, and <italic>intelligence</italic> sciences from the bottom up. They have not only been triggered by the information revolution and the rise of computational intelligence but also by the deepened understanding of the insights and generic principles of the natural science counterparts, in formal studies (Wang, <xref ref-type="bibr" rid="B31">2003</xref>, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B61">2022b</xref>; Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>, <xref ref-type="bibr" rid="B71">2021a</xref>).</p>
<fig id="F2" position="float">
<label>Figure 2</label>
<caption><p>Theoretical foundations of &#x003BA;<italic>C</italic>.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0002.tif"/>
</fig>
<p>The convergence of brain science (Wilson and Frank, <xref ref-type="bibr" rid="B84">1999</xref>; Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>), intelligence science (Boole, <xref ref-type="bibr" rid="B6">1854</xref>; Wang, <xref ref-type="bibr" rid="B39">2009a</xref>; Wang et al., <xref ref-type="bibr" rid="B80">2016b</xref>, <xref ref-type="bibr" rid="B81">2017</xref>; Widrow, <xref ref-type="bibr" rid="B82">2022</xref>), computer science (von Neumann, <xref ref-type="bibr" rid="B29">1946</xref>; Turing, <xref ref-type="bibr" rid="B26">1950</xref>; Wang, <xref ref-type="bibr" rid="B40">2009b</xref>), and intelligent mathematics (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B43">2012a</xref>,<xref ref-type="bibr" rid="B44">b</xref>, <xref ref-type="bibr" rid="B55">2020</xref>, <xref ref-type="bibr" rid="B62">2022c</xref>) has led to the emergence of &#x003BA;<italic>C</italic> (Wang, <xref ref-type="bibr" rid="B40">2009b</xref>, <xref ref-type="bibr" rid="B47">2012e</xref>), underpinned by the synergy of abstract sciences (Wang, <xref ref-type="bibr" rid="B61">2022b</xref>). This section provides a transdisciplinary review and analysis of the theoretical foundations, key discoveries, and technical breakthroughs toward realizing &#x003BA;<italic>C</italic> across the brain, computer, software, data, information, knowledge, intelligence, cybernetics, and mathematical sciences.</p>
<sec>
<title>2.1. Brain science</title>
<p>The brain as the most mature intelligent organ (Wilson and Frank, <xref ref-type="bibr" rid="B84">1999</xref>; Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>) is an ideal reference model for revealing the theoretical foundations of AI, and what AI may or not do, constrained by the nature and the expressive power of current mathematical means for computational implementations.</p>
<p><bold>Definition 3</bold>. <italic>Brain science</italic> studies the neurological and physiological structures of the brain and the mechanisms of intelligence generation on brain structures.</p>
<p>It is revealed in <italic>cognitive informatics</italic> (Wang, <xref ref-type="bibr" rid="B31">2003</xref>) that the brain and natural intelligence may be explained by a hierarchical framework, which maps the brain through embodiments at neurological, physiological, cognitive, and logical layers from bottom-up <italic>induction</italic> and top-down <italic>deduction</italic>. A rigorous study of the cognitive foundations of natural intelligence may shed light on the general mechanisms of all forms of intelligence toward pervasive <italic>brain-inspired systems</italic> (BIS) (Wang et al., <xref ref-type="bibr" rid="B80">2016b</xref>, <xref ref-type="bibr" rid="B73">2018</xref>).</p>
<p>A <italic>layered reference model of the brain</italic> (LRMB) (Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>) is introduced in <xref ref-type="fig" rid="F3">Figure 3</xref> as an overarching architecture of the brain&#x00027;s mechanisms. The four lower layers of LRMB, such as those of sensation, action, memory, and perception, are classified as subconscious mental functions of the brain, which are identified as the <italic>Brain&#x00027;s Operating System</italic> (BOS). However, the three higher layers encompassing those of cognition, inference, and intelligence are classified as conscious mental functions of the brain known as the <italic>Brain&#x00027;s Intelligence Generator</italic> (BIG) built on BOS.</p>
<fig id="F3" position="float">
<label>Figure 3</label>
<caption><p>Layered reference model of the brain (LRMB) (Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0003.tif"/>
</fig>
<p>LRMB reveals that the brain can be formally embodied by 52 cognitive processes (Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>) at seven recursive layers from the bottom up. In this view, any complex mental process or intelligent behavior is a temporary composition of fundamental processes of LRMB at run-time. Based on LRMB, the nature of intelligence may be rigorously reduced to lower-layer cognitive objects such as data, information, and knowledge in the following subsections. The framework of brain science and its functional explanations in cognitive science will be further explained in <bold>Figures 7</bold>, <bold>8</bold> in Sections 3, 4.</p>
<p>According to LRMB, the theoretical bottleneck and technical challenges toward &#x003BA;<italic>C</italic> are the lack of a fully autonomous intelligent engine at the top layer constrained by current <italic>pretrained AI</italic> and <italic>preprogramed computing</italic> technologies (Wang, <xref ref-type="bibr" rid="B40">2009b</xref>, <xref ref-type="bibr" rid="B57">2021b</xref>). Therefore, from the brain science point of view, &#x003BA;<italic>C</italic> is a brain-inspired intelligent computer for <italic>autonomous intelligence generation</italic> (AIG) dependent on an intelligent operating system, as designed in Section 4.</p></sec>
<sec>
<title>2.2. Computer science</title>
<p>A <italic>computer</italic> is a general programable machine for realizing computational intelligence (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B39">2009a</xref>). The odyssey toward &#x003BA;<italic>C</italic> has gone through mechanical (Charles Babbage) (Babbage, <xref ref-type="bibr" rid="B2">1822</xref>), analog, digital, and then quantum (David, <xref ref-type="bibr" rid="B8">1985</xref>) computers. Computing theories and models have been focused on information processing by various means and architectures (Lewis and Papadimitriou, <xref ref-type="bibr" rid="B15">1998</xref>; Wang, <xref ref-type="bibr" rid="B38">2008f</xref>). However, they are still stuck at low levels of reflexive, imperative, and adaptive intelligence according to the <italic>hierarchical intelligence model</italic> (HIM), as shown in <bold>Figure 5</bold>.</p>
<p><bold>Definition 4</bold>. <italic>Computer science</italic> studies the architectures and functions of general instructive processors, their denotational and operational mathematical models, programming languages, algorithmic frameworks, and run-time problem solutions interacting with the external environment.</p>
<p>A fundamental theory of computer science is built on the mathematical model of <italic>finite state machines</italic> (FSM) (Lewis and Papadimitriou, <xref ref-type="bibr" rid="B15">1998</xref>) and <italic>Turing machines</italic> (Turing, <xref ref-type="bibr" rid="B26">1950</xref>) as an event-driven behavioral generators in between the internal memory space and the external port (interface) space of users or devices (Wang, <xref ref-type="bibr" rid="B38">2008f</xref>).</p>
<p><bold>Definition 5</bold>. FSM is a universal function generator. Its <italic>structure</italic> &#x00398;(<italic>FSM</italic>) is a quin-tuple and its function <italic>F</italic>(<italic>FSM</italic>) is a sequence of state transitions of event-driven functions to realize programable intelligence in the external space:</p>
<disp-formula id="E3"><label>(2)</label><mml:math id="M4"><mml:mrow><mml:mi>F</mml:mi><mml:mi>S</mml:mi><mml:mi>M</mml:mi><mml:mo>&#x02259;</mml:mo><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable columnalign='left'><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mtext>&#x00398;</mml:mtext><mml:mo stretchy='false'>(</mml:mo><mml:mi>F</mml:mi><mml:mi>S</mml:mi><mml:mi>M</mml:mi><mml:mo stretchy='false'>)</mml:mo><mml:mo>=</mml:mo><mml:mo stretchy='false'>(</mml:mo><mml:mi>S</mml:mi><mml:mo>,</mml:mo><mml:mo>&#x003A3;</mml:mo><mml:mo>,</mml:mo><mml:mi>s</mml:mi><mml:mo>,</mml:mo><mml:mi>H</mml:mi><mml:mo>,</mml:mo><mml:mi>&#x003B4;</mml:mi><mml:mo stretchy='false'>)</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:mi>F</mml:mi><mml:mo stretchy='false'>(</mml:mo><mml:mi>F</mml:mi><mml:mi>S</mml:mi><mml:mi>M</mml:mi><mml:mo stretchy='false'>)</mml:mo><mml:mo>=</mml:mo><mml:munderover><mml:mi mathsize="20pt">R</mml:mi><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mi>s</mml:mi></mml:mrow><mml:mrow><mml:mo>&#x0007C;</mml:mo><mml:mi>S</mml:mi><mml:mo>&#x0007C;</mml:mo></mml:mrow></mml:munderover><mml:msub><mml:mi>&#x003B4;</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo>:</mml:mo><mml:msub><mml:mo>&#x003A3;</mml:mo><mml:mi>i</mml:mi></mml:msub><mml:mo>&#x000D7;</mml:mo><mml:msub><mml:mi>S</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo>&#x02192;</mml:mo><mml:msub><mml:mi>S</mml:mi><mml:mrow><mml:mi>i</mml:mi><mml:mo>+</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mi>S</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:menclose notation='updiagonalstrike'><mml:mo>&#x02282;</mml:mo></mml:menclose><mml:mi>H</mml:mi></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mrow></mml:math></disp-formula>
<p>where <italic>S</italic> is a finite set of predefined states of the FSM, <italic>&#x003A3;</italic> a set of events, <italic>s</italic> the initial state (<italic>s</italic> &#x02208; <italic>S</italic>), <italic>H</italic> the set of final states and &#x003B4; the state transition function. In Equation (2), the <italic>big-R calculus</italic> is a general recursive mathematical expression for denoting recurring structures or iterative behaviors (Wang, <xref ref-type="bibr" rid="B36">2008d</xref>), which is introduced in <italic>real-time process algebra</italic> (RTPA) (Wang, <xref ref-type="bibr" rid="B30">2002</xref>, <xref ref-type="bibr" rid="B33">2008a</xref>).</p>
<p>For processing complex mathematical and language expressions, Alan Turing extended an FSM to a more sophisticated computing model known as the Turing machine (Turing, <xref ref-type="bibr" rid="B26">1950</xref>) by enhanced recursive functions. Both the Turing machine and an FSM have provided a foundation for enabling programable intelligence in computer science.</p>
<p>However, in order to unleash the computational power from the first-generation of <italic>preprogramed (imperative)</italic> computers and the second-generation of <italic>pretrained</italic> (data aggregated) AI computers, to the third-generation of <italic>autonomous intelligent</italic> computers (Wang, <xref ref-type="bibr" rid="B47">2012e</xref>), &#x003BA;<italic>C</italic> is indispensable. The architecture and functions of &#x003BA;<italic>C</italic> will be elaborated in Section 3.</p></sec>
<sec>
<title>2.3. Software science</title>
<p><italic>Software</italic> is a form of abstract computational intelligence that is generated by <italic>instructive behaviors</italic> as a <italic>chain of embedded functions</italic> on executable <italic>computing structures</italic> as typed tuples (Wang, <xref ref-type="bibr" rid="B33">2008a</xref>, <xref ref-type="bibr" rid="B50">2014b</xref>). The latest advances in computer science, intelligence science, and intelligent mathematics have triggered the emergence of software science (Wang, <xref ref-type="bibr" rid="B50">2014b</xref>, <xref ref-type="bibr" rid="B59">2021d</xref>).</p>
<p><bold>Definition 6</bold>. The <italic>general mathematical model of software</italic> (GMMS) &#x02118; is a dispatch structure &#x021AA; with finite sets of embedded relational processes <italic>P</italic><sub><italic>i</italic></sub> driven by certain events (<italic>E</italic>):</p>
<disp-formula id="E4"><label>(3)</label><mml:math id="M5"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mtable style="text-align:axis;" equalrows="false" columnlines="left" equalcolumns="false" class="array"><mml:mtr><mml:mtd><mml:mi>&#x02118;</mml:mi><mml:mo>&#x02259;</mml:mo><mml:mstyle displaystyle="true"><mml:munderover accentunder="false" accent="false"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:munderover></mml:mstyle><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>&#x00040;</mml:mi><mml:msub><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">|E</mml:mtext><mml:mo>&#x021AA;</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>P</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">|PM</mml:mtext></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mo>=</mml:mo><mml:mstyle displaystyle="true"><mml:munderover accentunder="false" accent="false"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:munderover></mml:mstyle><mml:mrow><mml:mo stretchy="false">[</mml:mo><mml:mrow><mml:mi>&#x00040;</mml:mi><mml:msub><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">|E</mml:mtext><mml:mo>&#x021AA;</mml:mo><mml:mstyle displaystyle="true"><mml:munderover accentunder="false" accent="false"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow><mml:mrow><mml:mi>n</mml:mi><mml:mo>-</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:munderover></mml:mstyle><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msub><mml:mrow><mml:mi>p</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">(</mml:mtext><mml:mi>k</mml:mi><mml:mtext class="textrm" mathvariant="normal">)&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>r</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>,</mml:mo><mml:mi>i</mml:mi><mml:mo>&#x0002B;</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">(</mml:mtext><mml:mi>k</mml:mi><mml:mtext class="textrm" mathvariant="normal">)&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>p</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>&#x0002B;</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>k</mml:mi></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mtext class="textrm" mathvariant="normal">|PM</mml:mtext></mml:mrow><mml:mo stretchy="false">]</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where the abstract entities of software are represented by sets of <italic>structure models</italic> (SM), <italic>process models</italic> (PMs), and environmental events (<italic>E</italic>).</p>
<p>GMMS (Wang, <xref ref-type="bibr" rid="B50">2014b</xref>) reveals that software is not only an interactive dispatch structure at the top level driven by <italic>trigger, timing</italic>, and <italic>interrupt</italic> events (<italic>E</italic>), but also a set of embedded relational processes at the lower level of subsystems and components.</p>
<p><bold>Definition 7</bold>. <italic>Software science</italic> studies the formal properties and mathematical models of software, general methodologies for rigorous and efficient software development, and coherent theories and laws underpinning software behaviors and software engineering practices.</p>
<p>The discipline of software science (Hoare, <xref ref-type="bibr" rid="B9">1969</xref>, <xref ref-type="bibr" rid="B10">1994</xref>; Wang, <xref ref-type="bibr" rid="B50">2014b</xref>, <xref ref-type="bibr" rid="B59">2021d</xref>) encompasses theories and methodologies, denotational mathematics, system software, fundamental algorithms, organizational theories, cognitive complexity, and intelligent behavior generation theories. The pinnacle of software science is the set of fundamental theories of <italic>formal methods</italic> (Hoare, <xref ref-type="bibr" rid="B9">1969</xref>, <xref ref-type="bibr" rid="B10">1994</xref>; Hoare et al., <xref ref-type="bibr" rid="B11">1987</xref>; Wang, <xref ref-type="bibr" rid="B33">2008a</xref>, <xref ref-type="bibr" rid="B50">2014b</xref>, <xref ref-type="bibr" rid="B59">2021d</xref>) and platforms of system software including operating systems, compilers, database systems, and networked interconnections (Wang, <xref ref-type="bibr" rid="B38">2008f</xref>). Hoare has revealed that software is a <italic>mathematical entity</italic> (Hoare, <xref ref-type="bibr" rid="B9">1969</xref>) that may be formally denoted by a sequential behavioral process known as the <italic>unified process theory</italic> in formal methods (Hoare, <xref ref-type="bibr" rid="B10">1994</xref>).</p>
<p>A set of 30&#x0002B; laws of programming has been created by Hoare et al. (<xref ref-type="bibr" rid="B11">1987</xref>). Then, <italic>real-time process algebra</italic> (RTPA) (Wang, <xref ref-type="bibr" rid="B30">2002</xref>, <xref ref-type="bibr" rid="B37">2008e</xref>) has been introduced that extends Hoare&#x00027;s sequential process theory to a system of IM for formally denotating system and human cognitive, inference, and behavioral processes as a general theory toward <italic>software science</italic> (Wang, <xref ref-type="bibr" rid="B50">2014b</xref>). Based on RTPA, a comprehensive set of mathematical laws and associated theorems on software structures, behaviors, and processes has been formally established (Wang, <xref ref-type="bibr" rid="B34">2008b</xref>).</p>
<p><italic>Software engineering</italic> is applied software science that is one of the most complicated branches of engineering fields because its objects are highly abstract and intangible. It encompasses system modeling, architecture, development methodologies, programming technologies, and development platforms. It also covers heuristic principles, tools/environments, best practices, case studies, experiments, trials, and performance benchmarking.</p></sec>
<sec>
<title>2.4. Data science</title>
<p><italic>Data</italic> are an abstract representation of quantities or properties of real-world entities and abstract objects against a specific quantification scale. Data are the most fundamental and pervasive cognitive objects in the brain that link real-world entities and attributes to mental abstractions via <italic>sensation</italic> and <italic>quantification</italic>. Data are the most fundamental level of cognitive objects represented in the brain by its sensory, qualification, and abstraction processes for eliciting real-world attributes. The cognitive processes for data elicitation according to the LRMB model involve sensory, observation, abstraction, and measurement. However, data manipulations are dependent on qualification, qualification, measurement, statistics, and computing.</p>
<p><bold>Definition 8</bold>. <italic>Data</italic> with respect to a quantity <italic>X</italic> against a measuring scale &#x1D516;, <italic>D</italic>(<italic>X</italic>, &#x1D516;), is yielded via a <italic>quantification</italic> process &#x00393;<sub>&#x1D516;</sub>(<italic>X</italic>) that results in a real number, <inline-formula><mml:math id="M7"><mml:msubsup><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>X</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x1D516;</mml:mi></mml:mrow></mml:msubsup><mml:mo>.</mml:mo><mml:msubsup><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mi>X</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x1D516;</mml:mi></mml:mrow></mml:msubsup></mml:math></inline-formula>, in unit [&#x1D516;] denoted by the integer part <inline-formula><mml:math id="M8"><mml:msubsup><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>X</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x1D516;</mml:mi></mml:mrow></mml:msubsup></mml:math></inline-formula> and the decimal part <inline-formula><mml:math id="M9"><mml:msubsup><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mi>X</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x1D516;</mml:mi></mml:mrow></mml:msubsup></mml:math></inline-formula>, where the latter is given by the remainder:</p>
<disp-formula id="E5"><label>(4)</label><mml:math id="M6"><mml:mtable columnalign='left'><mml:mtr><mml:mtd><mml:mtext>&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;</mml:mtext><mml:mi>D</mml:mi><mml:mo stretchy='false'>(</mml:mo><mml:mi>X</mml:mi><mml:mo>,</mml:mo><mml:mi mathvariant='fraktur'>S</mml:mi><mml:mo stretchy='false'>)</mml:mo><mml:mo>&#x02259;</mml:mo></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:msub><mml:mtext>&#x00393;</mml:mtext><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msub><mml:mo stretchy='false'>(</mml:mo><mml:mi>X</mml:mi><mml:mo stretchy='false'>)</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:mo>=</mml:mo><mml:mfrac><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:mfrac><mml:mtext>&#x000A0;</mml:mtext><mml:mo>=</mml:mo><mml:msubsup><mml:mi>I</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mo>.</mml:mo><mml:msubsup><mml:mi>R</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mtext>&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi mathvariant='fraktur'>S</mml:mi><mml:mo stretchy='false'>]</mml:mo><mml:mo>,</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:mi mathvariant='fraktur'>S</mml:mi><mml:mo>&#x02208;</mml:mo><mml:mi>&#x0211D;</mml:mi><mml:mo>,</mml:mo><mml:msubsup><mml:mi>I</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mo>&#x02208;</mml:mo><mml:mi>&#x02124;</mml:mi><mml:mo>,</mml:mo><mml:mn>0</mml:mn><mml:mo>&#x02264;</mml:mo><mml:msubsup><mml:mi>R</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mo>&#x0003C;</mml:mo><mml:mi mathvariant='fraktur'>S</mml:mi></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext>&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;</mml:mtext><mml:mo>=</mml:mo><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable columnalign='left'><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:msubsup><mml:mi>I</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mo>=</mml:mo><mml:mi>m</mml:mi><mml:mi>o</mml:mi><mml:msub><mml:mi>d</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msub><mml:mo stretchy='false'>(</mml:mo><mml:mi>X</mml:mi><mml:mo stretchy='false'>)</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:msubsup><mml:mi>R</mml:mi><mml:mi>X</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msubsup><mml:mo>=</mml:mo><mml:mi>r</mml:mi><mml:mi>e</mml:mi><mml:msub><mml:mi>m</mml:mi><mml:mi mathvariant='fraktur'>S</mml:mi></mml:msub><mml:mo stretchy='false'>(</mml:mo><mml:mi>X</mml:mi><mml:mo stretchy='false'>)</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where &#x1D516; is represented by typical types encompassing bits (<italic>B</italic>), <italic>natural numbers</italic> (&#x02115;), <italic>integers</italic> (&#x02124;), real numbers <italic>(&#x0211D;</italic>), and <italic>fuzzy numbers</italic> (&#x1D53D;) in type theories (Wang, <xref ref-type="bibr" rid="B30">2002</xref>, <xref ref-type="bibr" rid="B50">2014b</xref>).</p>
<p><bold>Definition 9</bold>. <italic>Data science</italic> studies the basic properties of data encompassing their forms, types, properties, domains, representations, and formal mathematical models. It also studies data manipulation methodologies for data generation, acquisition, storage, retrieval, transformation, sharing, protection, and information aggregation.</p>
<p>In data science, <italic>big data</italic> are large-scale and heterogeneous data in terms of quantity, complexity, storage, retrieval, semantics, cognition, distribution, and maintenance in all branches of abstract sciences (Wang and Peng, <xref ref-type="bibr" rid="B74">2017</xref>) across Section 2.</p>
<p><bold>Definition 10</bold>. The <italic>mathematical model</italic> of <italic>big data</italic> &#x00398; is a two-dimensional <italic>n</italic> &#x000D7; <italic>m</italic> matrix where each row <inline-formula><mml:math id="M11"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>r</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mstyle class="text"><mml:mtext class="textrm" mathvariant="normal">SM</mml:mtext></mml:mstyle></mml:math></inline-formula> is denoted by a structure model (|SM) called a <italic>typed tuple</italic>; while each column <inline-formula><mml:math id="M12"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>j</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mi>j</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>j</mml:mi></mml:mrow></mml:msub></mml:math></inline-formula> is clustered by a <italic>field</italic> with a certain type (|T<sub>j</sub>):</p>
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mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow></mml:msub></mml:mtd><mml:mtd><mml:mo>&#x022EF;</mml:mo></mml:mtd><mml:mtd><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi><mml:mi>m</mml:mi></mml:mrow></mml:msub><mml:mtext>|</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:msub></mml:mtd></mml:mtr></mml:mtable></mml:mrow><mml:mo>]</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where each cell of big data <inline-formula><mml:math id="M14"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;</mml:mtext><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>j</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mi>j</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>j</mml:mi></mml:mrow></mml:msub></mml:math></inline-formula> formally denotes a certain object <italic>d</italic><sub><italic>ij</italic></sub> | <inline-formula><mml:math id="M105"><mml:mi mathvariant='double-struck'>T</mml:mi></mml:math></inline-formula><sub><italic>j</italic></sub> in type | <inline-formula><mml:math id="M106"><mml:mi mathvariant='double-struck'>T</mml:mi></mml:math></inline-formula><sub><italic>j</italic></sub>.</p>
<p><bold>Example 2</bold>. A formal BDS of a social network, &#x00398;(<italic>BDS</italic>), with a million users and seven data fields can be rigorously modeled by Equation (6), according to Definition 10.</p>
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<mml:mo>]</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>

<p>In Example 2, row zero &#x003B8;<sub>0</sub> in the mathematical model of BDS, &#x00398; (<italic>BDS</italic>), is a special typed tuple called the schema of the BDS, which specifies the structure and constraint of each data field of the BDS. It is noteworthy that the type suffixes | <italic>T</italic> adopted in the BDS model allow arbitrary type and media of big data to be rigorously specified in order to meet the requirements for accommodating widely heterogeneous data in the BDS, which will be specifically embodied by a certain type in applications.</p>
<p>The fundamental theory of data science may be explained by a set of rigorous data manipulations on &#x00398; by <italic>Big Data Algebra</italic> (BDA) (Wang, <xref ref-type="bibr" rid="B52">2016b</xref>). BDA provides a set of 11 algebraic operators in the categories of architectural modeling, analytic, and synthetic operations on the formal model of big data structure &#x00398;(BDA). In BDA, the <italic>modeling operators</italic> include schema specification and BDS initialization. The <italic>analytic operators</italic> encompass those of system assignment, retrieval, selection, time-stamp, and differentiation. The <italic>synthetic operators</italic> encompass those of induction, deduction, integration, and equilibrium detection.</p>
<p>BDA creates an algebraic system for rigorously manipulating big data systems &#x00398;(<italic>BDS</italic>) of intricate big datasets. It provides an efficient means for BDS modeling, design, specification, analysis, synthesis, refinement, validation, and complexity reduction as a general theory of data science (Wang and Peng, <xref ref-type="bibr" rid="B74">2017</xref>).</p></sec>
<sec>
<title>2.5. Information science</title>
<p><italic>Information</italic> is a general form of abstract objects and the signaling means for communication, interaction, and coordination, which are represented and transmitted by symbolical, mathematical, communication, computing, and cognitive systems. The source of information is sensory stimuli elicited from data by qualification or quantification. Any product and/or process of human mental activities results in information as a generic product of human thinking and reasoning that lead to knowledge. Information is the second-level cognitive object according to the CFB model (<xref ref-type="fig" rid="F1">Figure 1</xref>), which embodies the semantics of data collected from the real world or yielded by human cognitive processes.</p>
<p><bold>Definition 11</bold>. <italic>Information science</italic> studies forms, properties, and representations of information, as well as mathematical models and rules for information manipulations such as its generation, acquisition, storage, retrieval, transmission, sharing, protection, and knowledge aggregation.</p>
<p>In classic information theory (Shannon, <xref ref-type="bibr" rid="B23">1948</xref>), information is treated as a probabilistic measure of the properties of messages, signals, and their transmissions. It has focused on information transmission rather than the cognitive mechanisms of information and its manipulations. The measure of the quantity of information is highly dependent on the receiver&#x00027;s subjective judgment on probable properties of signals in the message as Shannon recognized.</p>
<p><bold>Definition 12</bold>. The <italic>Shannon information of</italic> an <italic>n-sign system, I</italic><sub><italic>s</italic></sub>, is determined by a weighted sum of the probabilities <italic>p</italic><sub>i</sub> and unexpectedness <italic>I</italic><sub>i</sub> of each sign in an information system:</p>
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<p>It is noteworthy that Shannon information measures the <italic>characteristic</italic> information of channel properties, which is not proportional to the size of a message transmitted in the channel. Therefore, classic information science has focused on symbolic information rather than the denotational and cognitive properties of information as given in Definitions 13 and 14.</p>
<p>The second generation of <italic>computational information science</italic> tends to model information as a deterministic abstract entity for data, messages, signals, memory, and knowledge representation and storage, rather than a probable property of communication channels as in the classic information theory. This notion reflexes the computational theories and practices across computer science, software science, the IT industry, and everyday lives (Turing, <xref ref-type="bibr" rid="B26">1950</xref>; Wang, <xref ref-type="bibr" rid="B50">2014b</xref>).</p>
<p><bold>Definition 13</bold>. The <italic>computational information, I</italic><sub><italic>c</italic></sub>, in contemporary information science is a normalized size of symbolic information of abstract object <italic>O</italic><sub><italic>k</italic></sub> represented in a <italic>k</italic>-based <italic>measure scale S</italic><sub><italic>k</italic></sub>:</p>
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<p>where <italic>I</italic><sub><italic>c</italic></sub> is deterministic and independent from Shannon&#x00027;s probabilistic information. In other words, the unit <italic>bit</italic> in computational information has been extended from Shannon&#x00027;s characteristic information of signals to the quantity of symbolic information in computer science.</p>
<p>However, it has been argued in cognitive information science that computational information as given in Definition 13 may still not represent the overall properties of generic information, particularly its semantic aspect (Wang, <xref ref-type="bibr" rid="B31">2003</xref>). This leads to the third generation of information science that models the essence of information as universal abstract artifacts and their symbolic representations, which can be acquired, memorized, and processed by human brains or computing systems. Theories of the third generation of information science are represented by <italic>cognitive Informatics</italic> (CI) (Wang, <xref ref-type="bibr" rid="B31">2003</xref>) as a transdisciplinary enquiry on the internal information processing mechanisms and processes of the brain (Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>).</p>
<p><bold>Definition 14</bold>. <italic>Cognitive information</italic>, <italic>I</italic><sub><italic>ci</italic></sub> &#x0003D; (<italic>I</italic><sub>&#x003BA;</sub>, <italic>I</italic><sub>&#x003A9;</sub>), is a 2D hyperstructure that represents a pair of <italic>characteristic</italic> information (<italic>I</italic><sub>&#x003BA;</sub>) and <italic>semantic</italic> information (<italic>I</italic><sub>&#x003A9;</sub>) on an arbitrary <italic>base</italic> &#x003B2; &#x02208; &#x02115; that determines the number of representative variables &#x003BA; &#x0003D; |<italic>v</italic><sub>1</sub>, <italic>v</italic><sub>2</sub>, ..., <italic>v</italic><sub>&#x003BA;</sub>|:</p>
<disp-formula id="E10"><label>(9)</label><mml:math id="M17"><mml:mrow><mml:msub><mml:mi>I</mml:mi><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mover><mml:mo>=</mml:mo><mml:mo>&#x02227;</mml:mo></mml:mover><mml:mtext>(</mml:mtext><mml:msub><mml:mi>I</mml:mi><mml:mi>&#x003BA;</mml:mi></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mi>I</mml:mi><mml:mtext>&#x003A9;</mml:mtext></mml:msub><mml:mtext>)</mml:mtext><mml:mo>=</mml:mo><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable columnalign='left'><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:msub><mml:mi>I</mml:mi><mml:mi>&#x003BA;</mml:mi></mml:msub><mml:mo>=</mml:mo><mml:mi>&#x003BA;</mml:mi><mml:msub><mml:mrow><mml:mtext>log</mml:mtext></mml:mrow><mml:mn>2</mml:mn></mml:msub><mml:mi>&#x003B2;</mml:mi><mml:mtext>&#x000A0;&#x000A0;&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>t</mml:mi><mml:mo stretchy='false'>]</mml:mo><mml:mtext>&#x000A0;&#x000A0;&#x000A0;</mml:mtext></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:msub><mml:mi>I</mml:mi><mml:mtext>&#x003A9;</mml:mtext></mml:msub><mml:mo>=</mml:mo><mml:msup><mml:mn>2</mml:mn><mml:mrow><mml:mrow><mml:mo>&#x02308;</mml:mo> <mml:mrow><mml:msub><mml:mi>I</mml:mi><mml:mi>&#x003BA;</mml:mi></mml:msub></mml:mrow> <mml:mo>&#x02309;</mml:mo></mml:mrow></mml:mrow></mml:msup><mml:mtext>&#x000A0;&#x000A0;</mml:mtext><mml:mo stretchy='false'>[</mml:mo><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>t</mml:mi><mml:mo stretchy='false'>]</mml:mo><mml:mtext>&#x000A0;&#x000A0;&#x000A0;</mml:mtext></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mrow></mml:math></disp-formula>
<p>where <italic>I</italic><sub>&#x003BA;</sub> is determined by the symbolic size of a certain problem dimension &#x003B2;, while <italic>I</italic><sub>&#x003A9;</sub> is generated by a normalized denotational space <inline-formula><mml:math id="M18"><mml:msup><mml:mrow><mml:mn>2</mml:mn></mml:mrow><mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:mrow></mml:msup><mml:mo>.</mml:mo></mml:math></inline-formula></p>
<p>The cognitive information model provided in Definition 14 reveals that the generalized semantic information is an inherent property of any system by both <italic>I</italic><sub>&#x003BA;</sub> and <italic>I</italic><sub>&#x003A9;</sub>. The measure of cognitive information is compatible with, but more general than, those of classic and computational information.</p>
<p><bold>Theorem 1</bold>. The <italic>framework of contemporary information science</italic> is constrained by the following relations among <italic>I</italic><sub><italic>s</italic></sub>, <italic>I</italic><sub><italic>c</italic></sub>, and <italic>I</italic><sub><italic>ci</italic></sub>:</p>
<disp-formula id="E11"><label>(10)</label><mml:math id="M19"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msub><mml:mo>&#x02208;</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi></mml:mrow></mml:msub><mml:mo>&#x0228F;</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:mtext class="textrm" mathvariant="normal">(</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mtext>&#x003A9;</mml:mtext></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">)</mml:mtext></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where &#x0228F; denotes a <italic>dimensional enclosure</italic> in a hyperstructure.</p>
<p><bold><italic>Proof</italic>. </bold>Theorem 1 holds directly based on Definitions 12&#x02013;14:</p>
<disp-formula id="E12"><label>(11)</label><mml:math id="M20"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mo>&#x02200;</mml:mo><mml:mtext>&#x000A0;&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">&#x000A0;and&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:mtext>&#x000A0;</mml:mtext></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext class="textrm" mathvariant="normal">because&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:mfrac><mml:mrow><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>O</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:mfrac><mml:mo>=</mml:mo><mml:mfrac><mml:mrow><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>.</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>O</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:mfrac><mml:mtext class="textrm" mathvariant="normal">&#x000A0;and&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>.</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow></mml:msub><mml:mo>&#x0228F;</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext class="textrm" mathvariant="normal">therefore&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>s</mml:mi></mml:mrow></mml:msub><mml:mo>&#x02208;</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi></mml:mrow></mml:msub><mml:mo>&#x0228F;</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>c</mml:mi><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:mtext class="textrm" mathvariant="normal">(</mml:mtext><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mrow><mml:mi>I</mml:mi></mml:mrow><mml:mrow><mml:mtext>&#x003A9;</mml:mtext></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">)</mml:mtext></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where the classic Shannon information <italic>I</italic><sub><italic>s</italic></sub> and computational information <italic>I</italic><sub><italic>s</italic></sub> become a special case of the characteristic information <italic>I</italic><sub>&#x003BA;</sub> in cognitive information science. &#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x025A0;</p>
<p>Contemporary and generalized information science explains that interpreted data result in information, while comprehended information generates knowledge.</p></sec>
<sec>
<title>2.6. Knowledge science</title>
<p><italic>Knowledge</italic> is modeled as a set of conceptual relations acquired and comprehended by the brain embodied as a concept network (Cios et al., <xref ref-type="bibr" rid="B7">2012</xref>; Wang, <xref ref-type="bibr" rid="B47">2012e</xref>, <xref ref-type="bibr" rid="B53">2016c</xref>). Knowledge is the third level of cognitive objects according to CFB as learned and comprehended information. Knowledge is perceived as a creative mental product generated by the brain embodied by <italic>concept networks</italic> and <italic>behavioral processes</italic>. The former represents the form of <italic>to-be</italic> knowledge, while the latter embodies the form of <italic>to-do</italic> knowledge that leads to the generation of human intelligence as elaborated in Section 2.7.</p>
<p>In traditional epistemology, knowledge is perceived as a justified belief (Wilson and Frank, <xref ref-type="bibr" rid="B84">1999</xref>). However, this perception is too narrow and subjective, and may not capture the essential essence of knowledge as a high-level cognitive entity aggregated from data and information.</p>
<p><bold>Definition 15</bold>. <italic>Knowledge science</italic> studies the nature of human knowledge, principles, and formal models of knowledge representation, as well as theories for knowledge manipulations such as creation, generation, acquisition, composition, memorization, retrieval, and repository in knowledge engineering.</p>
<p>The neurological foundation of knowledge may be explained by the synaptic connections among neurons representing the clusters of objects and attributes as shown in <xref ref-type="fig" rid="F4">Figure 4</xref>. The <italic>dynamic neural cluster</italic> (DNC) indicates that knowledge is not only retained in neurons as individual objects (<italic>O</italic>) or attributes (<italic>A</italic>), but also dynamically represented by the newly created synaptic connections modeled by relations such as <italic>r</italic>(<italic>O, A</italic>), <italic>r</italic>(<italic>A, O</italic>), <italic>r</italic>(<italic>O, O</italic>), and <italic>r</italic>(<italic>A, A</italic>) in <xref ref-type="fig" rid="F4">Figure 4</xref>. This leads to the development of the formal cognitive model of knowledge (Wang, <xref ref-type="bibr" rid="B32">2007</xref>).</p>
<fig id="F4" position="float">
<label>Figure 4</label>
<caption><p>OAR model of knowledge as dynamic neural clusters.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0004.tif"/>
</fig>
<p><bold>Definition 16</bold>. The <italic>Object-Attribute-Relation</italic> (<italic>OAR</italic>) <italic>model</italic> (Wang, <xref ref-type="bibr" rid="B32">2007</xref>) of knowledge in the brain is represented by a triple of neurological clusters:</p>
<disp-formula id="E13"><label>(12)</label><mml:math id="M21"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mi>O</mml:mi><mml:mi>A</mml:mi><mml:mi>R</mml:mi><mml:mover class="overset"><mml:mrow><mml:mo>=</mml:mo></mml:mrow><mml:mrow><mml:mo>&#x02227;</mml:mo></mml:mrow></mml:mover><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mtext class="textit" mathvariant="italic">O, A, R</mml:mtext></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where <italic>O</italic> is a set of objects identified by unique symbolic names, <italic>A</italic> the set of attributes for characterizing an object, and <italic>R</italic> the set of relations between the objects and attributes, i.e., <italic>R</italic> = <italic>O</italic> &#x000D7; <italic>A</italic>.</p>
<p>The OAR model reveals the nature and essence of knowledge and its neurological foundations. The OAR model may be adopted to explain a wide range of human information processing mechanisms and cognitive processes. It is different from the classic <italic>container</italic> metaphor of knowledge that failed to explain the dynamics of knowledge establishment and growth. The ORA model enables formal explanations of the structural model of human knowledge in the following mathematical model and theorem. Then, the semantical and functional theories of knowledge will be rigorously elaborated in concept algebra and semantic algebra in Section 2.9.</p>
<p><bold>Definition 17</bold>. The <italic>mathematical model of knowledge</italic> is a Cartesian product of power sets of formal concepts:</p>
<disp-formula id="E14"><label>(13)</label><mml:math id="M22"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mi>&#x1D50E;</mml:mi><mml:mo>=</mml:mo><mml:mi>&#x0211C;</mml:mi><mml:mo>:</mml:mo><mml:mstyle displaystyle="true"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi mathsize="20pt">X</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:munder></mml:mstyle><mml:msub><mml:mrow><mml:mi>C</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>&#x02192;</mml:mo><mml:mstyle displaystyle="true"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi mathsize="20pt">X</mml:mi></mml:mrow><mml:mrow><mml:mi>m</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>j</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:munder></mml:mstyle><mml:msub><mml:mrow><mml:mi>C</mml:mi></mml:mrow><mml:mrow><mml:mi>j</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mrow><mml:mo>[</mml:mo><mml:mrow><mml:mi>b</mml:mi><mml:mi>i</mml:mi><mml:mi>r</mml:mi></mml:mrow><mml:mo>]</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where the newly acquired concept <italic>C</italic><sub><italic>i</italic></sub> is mapped onto those already existing.</p>
<p>Equation (13) has led to one of the most fundamental discoveries in knowledge science (Wang, <xref ref-type="bibr" rid="B53">2016c</xref>) as follows.</p>
<p><bold>Theorem 2</bold>. The <italic>basic unit of knowledge</italic> is a pairwise conceptual relation, or shortly, a <italic>binary relation</italic> [<italic>bir</italic>].</p>
<p><bold><italic>Proof</italic>. </bold>According to Definition 17, knowledge as a mapping between two Cartesian products of concepts results in a deterministic set of relations. In which, any complex relationships can be reduced to the basic unit, <italic>bir</italic>, of knowledge between a pair of individual concepts. &#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x000A0;&#x025A0;</p>
<p>The formal theory of knowledge science is underpinned by <italic>concept algebra</italic> (Wang, <xref ref-type="bibr" rid="B41">2010</xref>) and <italic>semantic algebra</italic> (Wang, <xref ref-type="bibr" rid="B48">2013</xref>) in IM. It is recognized that concepts are the core model of human knowledge that carry stable semantics in expression, thinking, learning, reasoning, comprehension, and entity denotation. Although words in natural languages are often ambiguous and polymorphic, concepts elicited from them are not only unique in expressions but also neutral across different languages. Therefore, <italic>concept algebra</italic> is adopted to rigorously manipulate formal concepts and their algebraic operations for knowledge representation and semantic analyses. A set of algebraic operators of concept algebra has been created in Wang and Valipour (<xref ref-type="bibr" rid="B76">2016</xref>), Valipour and Wang (<xref ref-type="bibr" rid="B27">2016</xref>), which enables a wide range of applications in cognitive informatics, cognitive linguistics, and cognitive machine learning (Wang et al., <xref ref-type="bibr" rid="B75">2011</xref>).</p>
<p>In knowledge science, semantics is the carrier of language expressions and perceptions. In formal semantics, a comprehension of an expression is composed of the integrated meaning of a sentence&#x00027;s concepts and their relations. <italic>Semantic algebra</italic> is created for rigorous semantics manipulations in knowledge science by a set of rigorous <italic>relational, reproductive</italic>, and <italic>compositional</italic> operators (Wang, <xref ref-type="bibr" rid="B48">2013</xref>). On the basis of semantic algebra, semantic expressions may not only be deductively analyzed based on their syntactic structures from the top down, but also be synthetically composed by the algebraic semantic operators from the bottom up. Semantic algebra has enabled a wide range of applications in cognitive informatics, cognitive linguistics, cognitive computing, machine learning, cognitive robots, as well as natural language analysis, synthesis, and comprehension (Wang et al., <xref ref-type="bibr" rid="B77">2016a</xref>).</p></sec>
<sec>
<title>2.7. Intelligence science and AI</title>
<p>Intelligence science is the paramount level of abstract sciences according to the CFB model in <xref ref-type="fig" rid="F1">Figure 1</xref>.</p>
<p><bold>Definition 18</bold>. <italic>Intelligence &#x000EF;</italic> is either an internal <italic>inferential thread</italic> triggered by a cause <italic>c</italic><sub><italic>i</italic></sub> that results in inductive knowledge <italic>K</italic><sub><italic>i</italic></sub> or an interactive <italic>behavioral process B</italic><sub><italic>i</italic></sub> corresponding to an external or internal stimulus (event) <italic>e</italic><sub><italic>i</italic></sub>:</p>
<disp-formula id="E15"><label>(14)</label><mml:math id="M23"><mml:mrow><mml:mover accent='true'><mml:mi>&#x003B9;</mml:mi><mml:mo>&#x000A8;</mml:mo></mml:mover><mml:mo>&#x02259;</mml:mo><mml:mrow><mml:mo>{</mml:mo> <mml:mrow><mml:mtable columnalign='left'><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:munder><mml:mrow><mml:mover><mml:mi mathsize="20pt">R</mml:mi><mml:mi>m</mml:mi></mml:mover></mml:mrow><mml:mrow><mml:mi>k</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;(</mml:mtext><mml:msub><mml:mi>c</mml:mi><mml:mi>k</mml:mi></mml:msub><mml:mo>&#x02192;</mml:mo><mml:msub><mml:mi>K</mml:mi><mml:mi>k</mml:mi></mml:msub><mml:mo stretchy='false'>)</mml:mo><mml:mtext>&#x000A0;//&#x000A0;inferential&#x000A0;intelligence</mml:mtext></mml:mrow></mml:mtd></mml:mtr><mml:mtr columnalign='left'><mml:mtd columnalign='left'><mml:mrow><mml:munder><mml:mrow><mml:mover><mml:mi mathsize="20pt">R</mml:mi><mml:mi>n</mml:mi></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;(</mml:mtext><mml:msub><mml:mi>e</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo>&#x02192;</mml:mo><mml:msub><mml:mi>B</mml:mi><mml:mi>i</mml:mi></mml:msub><mml:mo stretchy='false'>)</mml:mo><mml:mtext>&#x000A0;//&#x000A0;behavioral&#x000A0;intelligence</mml:mtext></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:mrow> </mml:mrow></mml:mrow></mml:math></disp-formula>
<p>where the former is called <italic>inferential</italic> intelligence and the latter <italic>behavioral</italic> intelligence.</p>
<p>It is revealed that human and machine intelligence are dually aggregated from (sensory | data), (neural signaling | information), and (semantic networks | knowledge), to (autonomous behaviors | intelligence) in a recursive framework (Wang et al., <xref ref-type="bibr" rid="B71">2021a</xref>). In each pair of intelligent layers, the former is naturally embodied in neural structures of the brain, while the latter is represented in abstract (mathematical) forms in autonomous AI. Therefore, natural intelligence (NI) and AI are equivalent counterparts in philosophy and IM, which share a unified theoretical foundation in intelligence science as illustrated by LRMB in Section 2.1.</p>
<p><bold>Definition 19</bold>. <italic>Intelligence science</italic> studies the general form of <italic>abstract intelligence</italic> (&#x003B1;I) overarching natural and artificial intelligence and their theoretical foundations, which enable machines to generate advanced intelligence compatible with both human inferential and behavioral intelligence.</p>
<p>A <italic>Hierarchical Intelligence Model</italic> (HIM) (Wang et al., <xref ref-type="bibr" rid="B71">2021a</xref>) in intelligence science is introduced to explain the levels and categories of natural and machine intelligence as shown in <xref ref-type="fig" rid="F5">Figure 5</xref>. HIM explains why there was rarely fully autonomous intelligent system developed in the past 60&#x0002B; years because almost all such systems are constrained by the natural bottleneck of <italic>adaptiv</italic>e (L3-deterministic) intelligence underpinned by <italic>reflexive</italic> (L1-pretrained and data-driven), and <italic>imperative</italic> (L2-preprogramed) intelligence.</p>
<fig id="F5" position="float">
<label>Figure 5</label>
<caption><p>Hierarchical intelligence model (HIM) of intelligence science.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0005.tif"/>
</fig>
<p>According to HIM, the maturity levels of both human and machine intelligence are aggregated across the levels of <italic>reflexive, imperative, adaptive, autonomous</italic>, and <italic>cognitive</italic> intelligence from the bottom up in line with LRMB (Wang et al., <xref ref-type="bibr" rid="B78">2006</xref>) in brain science. HIM indicates that current AI technologies are still immature toward achieving human-like autonomous and conscious intelligence because the inherent problems faced by current AI technologies have been out of the domain of <italic>reflexive</italic> and <italic>regressive</italic> machine intelligence.</p>
<p><bold>Definition 20</bold>. The general pattern of <italic>abstract intelligence</italic> (&#x003B1;<italic>I</italic>) is a cognitive function <italic>f</italic><sub><italic>i</italic></sub> that enables an event <italic>e</italic><sub>i</sub>|T in the <italic>universe of discourse of abstract intelligence</italic>, <inline-formula><mml:math id="M24"><mml:msub><mml:mrow><mml:mi>&#x1D518;</mml:mi></mml:mrow><mml:mrow><mml:mover accent="true"><mml:mrow><mml:mi>&#x003B9;</mml:mi></mml:mrow><mml:mo>&#x000A8;</mml:mo></mml:mover></mml:mrow></mml:msub></mml:math></inline-formula>, to trigger a causal behavior <italic>B</italic><sub><italic>T</italic></sub>(<italic>i</italic>) |PM as a functional process:</p>
<disp-formula id="E16"><label>(15)</label><mml:math id="M25"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mi>a</mml:mi><mml:mi>I</mml:mi><mml:mover class="overset"><mml:mrow><mml:mo>=</mml:mo></mml:mrow><mml:mrow><mml:mo>&#x02227;</mml:mo></mml:mrow></mml:mover><mml:msub><mml:mrow><mml:mi>f</mml:mi></mml:mrow><mml:mrow><mml:mover accent="true"><mml:mrow><mml:mi>&#x003B9;</mml:mi></mml:mrow><mml:mo>&#x000A8;</mml:mo></mml:mover></mml:mrow></mml:msub><mml:mo>:</mml:mo><mml:mi>J</mml:mi><mml:mo>&#x000D7;</mml:mo><mml:mi>O</mml:mi><mml:mo>&#x000D7;</mml:mo><mml:mi>S</mml:mi><mml:mo>&#x000D7;</mml:mo><mml:mi>T</mml:mi><mml:mo>&#x02192;</mml:mo><mml:mi>B</mml:mi><mml:mo>,</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>J</mml:mi><mml:mo>,</mml:mo><mml:mi>O</mml:mi><mml:mo>,</mml:mo><mml:mi>B</mml:mi><mml:mo>,</mml:mo><mml:mi>S</mml:mi><mml:mo>,</mml:mo><mml:mi>T</mml:mi></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>&#x02208;</mml:mo><mml:msub><mml:mrow><mml:mi>&#x1D518;</mml:mi></mml:mrow><mml:mrow><mml:mover accent="true"><mml:mrow><mml:mi>&#x003B9;</mml:mi></mml:mrow><mml:mo>&#x000A8;</mml:mo></mml:mover></mml:mrow></mml:msub></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mo>=</mml:mo><mml:mstyle displaystyle="true"><mml:munderover accentunder="false" accent="false"><mml:mrow><mml:mi mathsize="20pt">R</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:munderover></mml:mstyle><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>&#x00040;</mml:mi><mml:msub><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">|T</mml:mtext><mml:mo>&#x021AA;</mml:mo><mml:msub><mml:mrow><mml:mi>B</mml:mi></mml:mrow><mml:mrow><mml:mi>T</mml:mi></mml:mrow></mml:msub><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi>i</mml:mi></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mtext>|</mml:mtext><mml:mi>P</mml:mi><mml:mi>M</mml:mi></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>,</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>e</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext class="textrm" mathvariant="normal">|T</mml:mtext><mml:mo>&#x02208;</mml:mo><mml:msub><mml:mrow><mml:mi>U</mml:mi></mml:mrow><mml:mrow><mml:mover accent="true"><mml:mrow><mml:mi>&#x003B9;</mml:mi></mml:mrow><mml:mo>&#x000A8;</mml:mo></mml:mover></mml:mrow></mml:msub><mml:mo>.</mml:mo><mml:mtext>T</mml:mtext></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where <inline-formula><mml:math id="M26"><mml:mrow><mml:msub><mml:mi mathvariant='fraktur'>U</mml:mi><mml:mover accent='true'><mml:mi>&#x003B9;</mml:mi><mml:mo>&#x000A8;</mml:mo></mml:mover></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>&#x02259;</mml:mo><mml:mo stretchy='false'>(</mml:mo><mml:mi>J</mml:mi><mml:mo>,</mml:mo><mml:mi>O</mml:mi><mml:mo>,</mml:mo><mml:mi>B</mml:mi><mml:mo>,</mml:mo><mml:mi>S</mml:mi><mml:mo>,</mml:mo><mml:mi>T</mml:mi><mml:mo stretchy='false'>)</mml:mo></mml:mrow></mml:math></inline-formula> denotes the 5D behavioral space of humans and intelligent systems constrained by the <italic>subject</italic> (<italic>J</italic>), <italic>object</italic> (<italic>O</italic>), <italic>behaviors</italic> (<italic>B</italic>), <italic>space</italic> (<italic>S</italic>), and <italic>time</italic> (<italic>T</italic>). The symbol &#x021AA; denotes the <italic>dispatching</italic> operator, |T the type of events classified as <italic>trigger, timing</italic>, or <italic>interrupt</italic> requests, and |PM the type suffix of a process model for a certain behavior (Wang, <xref ref-type="bibr" rid="B30">2002</xref>).</p>
<p>The advances of intelligence science have provided primitive theories for the odyssey toward &#x003BA;<italic>C</italic> powered by IM, particularly <italic>Real-Time Process Algebra</italic> (RTPA) (Wang, <xref ref-type="bibr" rid="B30">2002</xref>) and <italic>Inference Algebra</italic> (Wang, <xref ref-type="bibr" rid="B42">2011</xref>, <xref ref-type="bibr" rid="B45">2012c</xref>) inspired by Newton (<xref ref-type="bibr" rid="B17">1729</xref>), Boole (<xref ref-type="bibr" rid="B6">1854</xref>), Russell (<xref ref-type="bibr" rid="B21">1903</xref>), Hoare (<xref ref-type="bibr" rid="B9">1969</xref>), Kline (<xref ref-type="bibr" rid="B14">1972</xref>), <xref ref-type="bibr" rid="B1">Aristotle (384 BC&#x02212;322 BC</xref>) (<xref ref-type="bibr" rid="B1">1989</xref>), Zadeh (<xref ref-type="bibr" rid="B85">1997</xref>), Bender (<xref ref-type="bibr" rid="B3">2000</xref>), Timothy (<xref ref-type="bibr" rid="B25">2008</xref>), and Widrow (<xref ref-type="bibr" rid="B82">2022</xref>).</p></sec>
<sec>
<title>2.8. Cybernetics 2.0</title>
<p>Norbert Wiener invented the word <italic>cybernetics</italic> and wrote a book by that name on the subject of feedback and control in the human body (Wiener, <xref ref-type="bibr" rid="B83">1948</xref>). Widrow&#x00027;s new book (Widrow, <xref ref-type="bibr" rid="B82">2022</xref>), &#x0201C;<italic>Cybernetics 2.0: a General Theory of Adaptivity and Homeostasis in the Brain and in the Body</italic>&#x0201D; follows in Wiener&#x00027;s footsteps. It is different as it introduces learning algorithms to Wiener&#x00027;s subject because learning algorithms did not exist in Wiener&#x00027;s day. Our current knowledge of biologically plausible networks for information flow is still limited. Most research focuses on neurons, but there is a world of complexity due to glial cells like astrocytes which surround them and densely pack and provide the energy for synaptic events (Salmon et al., <xref ref-type="bibr" rid="B22">2023</xref>).</p>
<p>Through synapses of neurons in the brain, information is carried between neurotransmitters and neuroreceptors. Synapse is the coupling device from/to neuron. The strength of the coupling, the &#x0201C;weight&#x0201D;, is proportional to the number of receptors. Their numbers can increase or decrease, such as upregulation or downregulation. A mystery in neuroscience is, what is nature&#x00027;s algorithm for controlling upregulation and downregulation? Start with Hebbian learning and generalize it to cover downregulation, upregulation, and inhibitory, as well as excitatory synapses. What results is a surprise! We have an unsupervised form of the LMS (least mean square) algorithm of Widrow and Hoff. The Hebbian-LMS algorithm encompasses Hebb&#x00027;s learning rule (fire together, wire together), and introduces homeostasis into the equation. A neuron&#x00027;s &#x0201C;normal&#x0201D; firing rate is set by homeostasis. Physical evidence supports Hebbian-LMS as being nature&#x00027;s learning rule. LMS binds nature&#x00027;s learning to learning in artificial neural networks.</p>
<p>The Hebbian-LMS algorithm is key to the control of all the organs of the body, where hormones bind to hormonereceptors and there is upregulation and downregulation in the control process. Hebbian-LMS theory has a wide range of applications, explaining observed physiological phenomena regarding, for example, pain and pleasure, opioid addiction and withdrawal, blood pressure, blood salinity, kidney function, and thermoregulaion of the body&#x00027;s temperature. Upregulation and downregulation are even involved in viral infection and cancer. Countless variables are controlled by the same algorithm for modulating adaptivity and learning with billions of synapses in the brain.</p></sec>
<sec>
<title>2.9. Mathematical science and contemporary intelligent mathematics</title>
<p><italic>Mathematics</italic> is the most fundamental branch of abstract sciences for manipulating contemporary entities toward &#x003BA;<italic>C</italic>. The history of sciences and engineering has revealed that the kernel of human knowledge has been elicited and archived in generic mathematical forms (Wang, <xref ref-type="bibr" rid="B55">2020</xref>, <xref ref-type="bibr" rid="B58">2021c</xref>, <xref ref-type="bibr" rid="B62">2022c</xref>) as evidenced in the transdisciplinary reviews of the previous subsections. Therefore, the maturity of any scientific discipline is dependent on the readiness of its mathematical means.</p>
<p><bold>Definition 21</bold>. <italic>Intelligent Mathematics</italic> (IM) is a category of contemporary mathematics that deals with complex mathematical entities in the domain of <italic>hyperstructures</italic> <italic>(&#x0210D;</italic>), beyond those of &#x0211D; and <inline-formula><mml:math id="M107"><mml:mi mathvariant='double-struck'>B</mml:mi></mml:math></inline-formula>, by a series of embedded functions and processes in order to formalize rigorous expressions, inferences, and computational intelligence.</p>
<p>An interesting discovery in IM (Wang, <xref ref-type="bibr" rid="B55">2020</xref>) is that almost all <italic>Abstract Objects</italic> (AO) in modern sciences, such as data, information, knowledge, and intelligence as illustrated in <xref ref-type="fig" rid="F6">Figure 6</xref>, cannot be rigorously modeled and manipulated by pure numbers (Wang, <xref ref-type="bibr" rid="B35">2008c</xref>, <xref ref-type="bibr" rid="B44">2012b</xref>, <xref ref-type="bibr" rid="B69">2023</xref>). In order to deal with this <italic>denotational crisis of mathematics</italic> (Wang, <xref ref-type="bibr" rid="B62">2022c</xref>), the mathematical means for manipulating <italic>AO</italic> must be adapted to allow &#x003BA;<italic>C</italic>s to sufficiently handle the <italic>nonnumerical hyperstructures</italic> of <italic>AO</italic> for autonomous knowledge and intelligence processing.</p>
<fig id="F6" position="float">
<label>Figure 6</label>
<caption><p>Framework of IMs underpinning &#x003BA;<italic>C</italic>.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0006.tif"/>
</fig>
<p>The theoretical framework of IM is described in <xref ref-type="fig" rid="F6">Figure 6</xref> which explains the causality of what <italic>AO</italic> has triggered the development of which IM paradigm. It also describes the applications of each contemporary IM in &#x003BA;<sc>C</sc> for meeting the indispensable demands in symbiotic and autonomous human&#x02013;machine interactions.</p>
<p>Although classic mathematics has provided a wide range of abstract means for manipulating abstract numbers dominated in &#x0211D;, it has been fundamentally challenged by the demands in knowledge and intelligence sciences where the cognitive entities are no longer pure numbers. These contemporary demands have triggered the emergence of IM, which provides a family of advanced denotational means for extending classic numerical analytic mathematics in &#x0211D; to more general categories of abstract entities in &#x0210D; as explained in <xref ref-type="fig" rid="F6">Figure 6</xref>. IM has extended traditional <italic>Boolean algebra</italic> (as well as bivalent logic) on <inline-formula><mml:math id="M108"><mml:mi mathvariant='double-struck'>B</mml:mi></mml:math></inline-formula> and <italic>analytic algebra</italic> on &#x0211D; to more complex and multi-dimensional hyperstructures (&#x0210D;) in order to enable humans and/or intelligent machines to manipulate compatible knowledge and symbiotic intelligent behaviors across platforms via &#x003BA;<italic>C</italic> for efficiently processing the <italic>nonnumerical</italic> cognitive entities characterized by &#x0210D;.</p>
<p>The framework of IM demonstrates a set of most important basic research on the theoretical foundations of &#x003BA;<italic>C</italic>. The design and implementation of &#x003BA;<italic>C</italic> have been enabled by IM and related theoretical and technical advances as reviewed in previous subsections. IM has shed light on the systematical solving of challenging natural/artificial intelligence problems by a rigorous and generic methodology. A pinnacle of IM is the recent proofs of the world&#x00027;s top-10 hardest problems in number theory known as the <italic>Goldbach conjecture</italic> (Wang, <xref ref-type="bibr" rid="B63">2022d</xref>,<xref ref-type="bibr" rid="B65">f</xref>,<xref ref-type="bibr" rid="B67">h</xref>) and the <italic>Twin-Prime conjecture</italic> (Wang, <xref ref-type="bibr" rid="B64">2022e</xref>,<xref ref-type="bibr" rid="B68">i</xref>). IM has led to unprecedented theories and methodologies for implementing &#x003BA;<italic>C</italic> toward autonomous intelligence generation.</p></sec></sec>
<sec id="s3">
<title>3. The architecture and functions of <italic>&#x003BA;C</italic> for autonomous intelligence generation</title>
<p>The transdisciplinary synergy of basic research and technical innovations in Section 2 has provided a theoretical foundation and rational roadmap for the development of &#x003BA;<sc>C.</sc></p>
<p>The odyssey toward &#x003BA;<sc>C</sc> indicates that the counterpart of human intelligence may not be in the classic form of special- purpose AI, rather than be more generic &#x003BA;<sc>C<bold>-</bold></sc>enabled autonomous intelligence inspired by the brain on a symbiotic man-machine computing platform. The key transdisciplinary discoveries and mathematical breakthroughs in Section 2 have enabled the invention of &#x003BA;<sc>C</sc> and its development. They have also demonstrated the indispensable value of basic research devoted by the International Institute of Cognitive Informatics and Cognitive Computing (I2CICC) in the past two decades (Wang et al., <xref ref-type="bibr" rid="B79">2021b</xref>).</p>
<p>This section presents the architectural and functional framework of &#x003BA;<italic>C</italic> for the next-generation autonomous intelligent computers. The brain-inspired architecture and the hierarchical intelligent functions of &#x003BA;<italic>C</italic> will be formally described and elaborated. It leads to a demonstration of how &#x003BA;<italic>C</italic> works for autonomous knowledge learning toward machine intelligence generation among other AAI functions modeled in <xref ref-type="fig" rid="F3">Figure 3</xref>.</p>
<sec>
<title>3.1. Architecture of <italic>&#x003BA;C</italic></title>
<p>&#x003BA;<italic>C</italic> is designed as a BIS for advancing classic computers from data processors to the next generation of knowledge and intelligence processors mimicking the brain. It studies natural intelligence models of AAI as a cognitive system in one direction, and the formal models of the brain simulated by computational intelligence in the other direction.</p>
<p><bold>Definition 22</bold>. &#x003BA;<italic>C</italic> is a brain-equivalent intelligent computer that implements autonomous computational intelligence enabled by IM. Let &#x003BA;<sup>0</sup> through &#x003BA;<sup>4</sup> be the hierarchical layers of cognitive objects of data (<inline-formula><mml:math id="M109"><mml:mi mathvariant='double-struck'>D</mml:mi></mml:math></inline-formula>), information (<inline-formula><mml:math id="M110"><mml:mi mathvariant='double-struck'>I</mml:mi></mml:math></inline-formula>), knowledge (<inline-formula><mml:math id="M111"><mml:mi mathvariant='double-struck'>K</mml:mi></mml:math></inline-formula>), and intelligence (<inline-formula><mml:math id="M27"><mml:mover accent="true"><mml:mrow><mml:mi mathvariant='double-struck'>I</mml:mi></mml:mrow><mml:mo>&#x022C5;</mml:mo></mml:mover></mml:math></inline-formula>), the autonomous generation of intelligence by a &#x003BA;<italic>C</italic> is formally modeled by a recursive structure:</p>
<disp-formula id="E17"><label>(16)</label><mml:math id="M28"><mml:mtable class="eqnarray" columnalign="left"><mml:mtr><mml:mtd><mml:mi>&#x003BA;</mml:mi><mml:mi>C</mml:mi><mml:mover class="overset"><mml:mrow><mml:mo>=</mml:mo></mml:mrow><mml:mrow><mml:mo>&#x02227;</mml:mo></mml:mrow></mml:mover><mml:mstyle displaystyle="true"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mtext mathsize="20pt">R</mml:mtext></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>k</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:munder></mml:mstyle><mml:mtext>&#x000A0;</mml:mtext><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi></mml:mrow></mml:msup><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mi>k</mml:mi><mml:mo>-</mml:mo><mml:mn>1</mml:mn></mml:mrow></mml:msup></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow><mml:mo>,</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>0</mml:mn></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mstyle displaystyle="true"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mtext mathsize="20pt">R</mml:mtext></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder></mml:mstyle><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext>|</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext>&#x000A0;</mml:mtext><mml:mo>=</mml:mo><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msup><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msup><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msup><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow></mml:msup><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi>&#x003BA;</mml:mi></mml:mrow><mml:mrow><mml:mn>0</mml:mn></mml:mrow></mml:msup></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mtd></mml:mtr><mml:mtr><mml:mtd><mml:mtext>&#x000A0;</mml:mtext><mml:mo>=</mml:mo><mml:mover accent="true"><mml:mrow><mml:mi mathvariant='double-struck'>I</mml:mi></mml:mrow><mml:mo>.</mml:mo></mml:mover><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi mathvariant='double-struck'>K</mml:mi><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mi mathvariant='double-struck'>D</mml:mi><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mstyle displaystyle="true"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mtext mathsize="20pt">R</mml:mtext></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder></mml:mstyle><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext>|</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mtd></mml:mtr></mml:mtable></mml:math></disp-formula>
<p>where each cognitive layer (&#x003BA;<sup><italic>k</italic></sup>) is enabled by its lower adjacent layer (&#x003BA;<sup><italic>k</italic></sup>&#x02212;1) till the cognitive hierarchy is terminated at the bottom sensorial layer (&#x003BA;<sup>0</sup>), which is embodied by <italic>n</italic>&#x0002B;1 dimensional data,<inline-formula><mml:math id="M29"><mml:munder><mml:mrow><mml:mover class="overset"><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:mover></mml:mrow><mml:mrow><mml:mi>i</mml:mi><mml:mo>=</mml:mo><mml:mn>0</mml:mn></mml:mrow></mml:munder><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>i</mml:mi></mml:mrow></mml:msub><mml:mo>=</mml:mo><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mn>0</mml:mn></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mn>0</mml:mn></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn></mml:mrow></mml:msub><mml:mo>,</mml:mo><mml:mo>.</mml:mo><mml:mo>.</mml:mo><mml:mo>.</mml:mo><mml:mo>,</mml:mo><mml:msub><mml:mrow><mml:mi>d</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msub><mml:mtext>&#x000A0;</mml:mtext><mml:mo>|</mml:mo><mml:mtext>&#x000A0;</mml:mtext><mml:msub><mml:mrow><mml:mi mathvariant='double-struck'>T</mml:mi></mml:mrow><mml:mrow><mml:mi>n</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:math></inline-formula> as acquired by abstraction and quantification. The <italic>type-suffix</italic> |T is adopted to denote the semantic category of a variable <italic>x</italic> by <italic>x</italic>|T. Typical types for modeling intelligent behaviors of &#x003BA;<italic>C</italic> have been given in Definition 22.</p>
<p>The <italic>architectural model</italic> of &#x003BA;<italic>C</italic> is illustrated in <xref ref-type="fig" rid="F7">Figure 7</xref> as a brain-inspired computer. In the &#x003BA;<italic>C</italic> architecture, each component has a corresponding organ in the brain that shares similar functions. This design reflects the essence of BIS synergized in Section 2. The kernel of &#x003BA;<italic>C</italic> is embodied by the <italic>inference</italic> and <italic>conscious engines</italic> equivalent to the <italic>thalamus</italic> and <italic>the hyperthalamus</italic> of the brain (Wang, <xref ref-type="bibr" rid="B46">2012d</xref>), respectively, according to the LRMB model as shown in <xref ref-type="fig" rid="F3">Figure 3</xref>. It is noteworthy that the cognitive memories in the brain encompass <italic>short-term</italic> memory (STM), <italic>long-term</italic> memory (LTM), <italic>sensory buffer</italic> memory (SBM), <italic>action buffer</italic> memory (ABM), and <italic>conscious status</italic> memory (CSM) as shown in <xref ref-type="fig" rid="F7">Figure 7</xref> <xref ref-type="fig" rid="F7">Figure 7</xref> (Wang, <xref ref-type="bibr" rid="B46">2012d</xref>), which play important roles for supporting intelligence generation and operation. However, they are not the kernel organs of natural intelligence, rather than buffers and storages in the brain. Therefore, all memory structures may be unified in &#x003BA;<italic>C</italic> as a general memory space that may be partitioned into special sections.</p>
<fig id="F7" position="float">
<label>Figure 7</label>
<caption><p>Architecture of &#x003BA;<italic>C</italic>.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0007.tif"/>
</fig>
</sec>
<sec>
<title>3.2. Functions of <italic>&#x003BA;C</italic></title>
<p>The <italic>functional model</italic> of &#x003BA;<italic>C</italic>, as shown in <xref ref-type="fig" rid="F8">Figure 8</xref>, is designed based on the HIM model (<xref ref-type="fig" rid="F5">Figure 5</xref>) of intelligence science (Wang, <xref ref-type="bibr" rid="B46">2012d</xref>). Adopting HIM as a blueprint for the behavior model of &#x003BA;<italic>C</italic>, an <italic>Intelligent Operating System</italic> (IOS) of &#x003BA;<italic>C</italic>, &#x003BA;<italic>C</italic>-IOS, is designed as shown in <xref ref-type="fig" rid="F9">Figure 9</xref>. &#x003BA;<italic>C</italic>-IOS provides a rigorous <italic>Mathematical Framework of Hierarchical Intelligence</italic> (MFHI) for &#x003BA;<italic>C</italic>. The Intelligent Behavioral Model of &#x003BA;<italic>C</italic> configured by the MFHI framework forms a theoretical foundation for explaining what the spectrum of natural intelligence is, and how they are generated by &#x003BA;<italic>C</italic> in computational intelligence.</p>
<fig id="F8" position="float">
<label>Figure 8</label>
<caption><p>Intelligent functions of &#x003BA;<italic>C</italic> built on the layered reference model of the brain (LRMB).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0008.tif"/>
</fig>
<fig id="F9" position="float">
<label>Figure 9</label>
<caption><p>Intelligent operating system of &#x003BA;<italic>C</italic> (&#x003BA;<italic>C</italic>-IOS).</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0009.tif"/>
</fig>
<p>The &#x003BA;<italic>C</italic>-IOS model explains why the current level of machine intelligence has been stuck at the adaptive level of <inline-formula><mml:math id="M30"><mml:msub><mml:mover><mml:mi mathvariant='double-struck'>I</mml:mi><mml:mo>.</mml:mo></mml:mover><mml:mrow><mml:mi>a</mml:mi><mml:mi>d</mml:mi><mml:mi>p</mml:mi></mml:mrow></mml:msub></mml:math></inline-formula> for over 60&#x0002B; years. It also elaborates why fully autonomous intelligence could not be implemented by current pretrained AI technologies in real-time applications.</p>
<p>In the framework of &#x003BA;<italic>C</italic>-IOS, the <italic>inference engine</italic> of &#x003BA;<italic>C</italic> for intelligent behavior generation is implemented from the bottom-up encompassing: L1) the <italic>reflective</italic> (sensory-driven) intelligence, L2) the <italic>imperative</italic> intelligence; L3) the <italic>adaptive</italic> intelligence, L4) the <italic>autonomous</italic> intelligence, and L5) the <italic>cognitive</italic> intelligence. &#x003BA;<italic>C</italic>-IOS enables &#x003BA;<italic>C</italic> to think (the <italic>inferential</italic> intelligence) and action (the <italic>behavioral</italic> intelligence) as defined in the mathematical model of intelligence (Equation 14) toward AAI by mimicking the brain beyond classical preprogramed computers or the pre-trained special purpose AI technologies.</p>
<p>Each form of the 16 intelligence functions compatible between the brain and &#x003BA;<italic>C</italic> is coupled by the generic pattern of intelligence as an event-triggered dispatching mechanism (Wang, <xref ref-type="bibr" rid="B30">2002</xref>) formulated in Definition 20. The mathematical models developed in <xref ref-type="fig" rid="F9">Figure 9</xref> reveal that intelligent computers may be extended from the narrow sense in Section 2.7 to a broad sense of &#x003BA;<italic>C</italic> for autonomous intelligence generation. The intelligent behaviors of &#x003BA;<italic>C</italic> are aggregated from the bottom-up as shown in <xref ref-type="fig" rid="F9">Figure 9</xref>, particularly those at Level 5 such as knowledge-based, learning-driven, inference-driven, and inductive intelligence in order to enable the highest level of system intelligence mimicking human brains. Therefore, &#x003BA;<italic>C</italic> will overcome the classical constraints inherited in the pretrained and preprogrammed computing approaches for implementing the expected intelligent computers.</p></sec></sec>
<sec id="s4">
<title>4. Paradigms of <italic>&#x003BA;C</italic> for autonomous knowledge learning and machine intelligence generation</title>
<p>The fundamental AAI kernel of &#x003BA;<italic>C</italic> has been implemented based on the design in <xref ref-type="fig" rid="F8">Figures 8</xref>, <xref ref-type="fig" rid="F9">9</xref> (Wang, <xref ref-type="bibr" rid="B47">2012e</xref>). &#x003BA;<italic>C</italic> is driven by a set of autonomous algorithms formally described in RTPA (Wang, <xref ref-type="bibr" rid="B30">2002</xref>), which are autonomously executed by &#x003BA;<italic>C</italic> for enabling AAI (non-pretrained or non-preprogrammed) intelligence.</p>
<p>One of the key breakthroughs of &#x003BA;<italic>C</italic> is autonomous knowledge learning enabled by Level-5 cognitive intelligence according to <xref ref-type="fig" rid="F5">Figure 5</xref> (Wang, <xref ref-type="bibr" rid="B60">2022a</xref>), (Valipour and Wang, <xref ref-type="bibr" rid="B28">2017</xref>). According to HIM, the abilities for knowledge learning and reasoning are an indispensable foundation for intelligence generation by &#x003BA;<italic>C</italic>. In other words, traditional data-driven AI may not necessarily lead to generic and autonomous machine intelligence, because it is trained for specific purposes. This observation reveals a fundamental difference between &#x003BA;<italic>C</italic> and classical data-regressive AI technologies.</p>
<p>The cognitive informatics model of language comprehension is a cognitive process according to the LRMB and OAR models of internal knowledge representation (Wang, <xref ref-type="bibr" rid="B32">2007</xref>; Wang et al., <xref ref-type="bibr" rid="B75">2011</xref>, <xref ref-type="bibr" rid="B77">2016a</xref>). A rigorous description of the cognitive process of comprehension has been formally described in Wang (<xref ref-type="bibr" rid="B40">2009b</xref>, <xref ref-type="bibr" rid="B57">2021b</xref>). The cognitive model between a language expression and its syntaxes and semantics may be explained as shown in <xref ref-type="fig" rid="F10">Figure 10</xref> known as the <italic>universal language comprehension</italic> (ULC) model (Wang and Berwick, <xref ref-type="bibr" rid="B70">2012</xref>). <xref ref-type="fig" rid="F10">Figure 10</xref> explains that linguistic analyses are a deductive process that maps the 1-D language expression L into a 5-D semantic space C via 2-D syntactical analyses S, where C is determined by the dimensions of the subject (<italic>J</italic>), the object (<italic>O</italic>), the action (<italic>A</italic>), the space (<italic>S</italic>), and the time point (<italic>T</italic>).</p>
<fig id="F10" position="float">
<label>Figure 10</label>
<caption><p>The universal language comprehension (ULC) model.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0010.tif"/>
</fig>
<p>The ULC model indicates that syntactic analysis is a coherent part of semantic comprehension in formal language processing and machine knowledge learning by &#x003BA;<italic>C</italic>. It is found that the <italic>semantics</italic> of a sentence in a natural language expression may be comprehended by &#x003BA;<italic>C iff</italic> : (a) The parts of speech in the given sentence are analytically identified; (b) All parts of speech of the sentence are reduced to the terminals <italic>W</italic><sup>0</sup>, which are a predefined real-world entity, a primitive abstract concept, or a derived behavior; and (c) The individual semantics of each part of speech and their logical relations are synthesized into a coherent structure.</p>
<p>According to the ULC theory, the methodology for knowledge learning by &#x003BA;<italic>C</italic> is a semantic cognition process enabled by a <italic>language comprehension engine</italic> (LCE) (Wang, <xref ref-type="bibr" rid="B53">2016c</xref>). LCE is implemented in a closed loop of syntactic analysis, semantic deduction, and semantic synthesis for enabling the entire process of semantic comprehension by &#x003BA;<italic>C</italic>. LCE is supported by a <italic>cognitive knowledge base</italic> (CKB) (Wang, <xref ref-type="bibr" rid="B49">2014a</xref>). In CKB, machine knowledge is rigorously represented by a cognitive mapping between a newly acquired concept against known ones in the CKB of &#x003BA;<italic>C</italic> based on Definition 17.</p>
<p>An experiment for autonomous &#x003BA;<italic>C</italic> learning has been conducted in a pilot project of autonomous (unsupervised) knowledge learning and semantic cognition driven by <italic>concept algebra</italic> (Wang, <xref ref-type="bibr" rid="B41">2010</xref>, <xref ref-type="bibr" rid="B49">2014a</xref>), and <italic>semantic algebra</italic> (Wang, <xref ref-type="bibr" rid="B48">2013</xref>). In autonomous knowledge learning, &#x003BA;<italic>C</italic> adopts a relational neural cluster structure for knowledge representation in CKB as illustrated in <xref ref-type="fig" rid="F4">Figure 4</xref>. The set of knowledge acquired by &#x003BA;<italic>C</italic> for the first 600&#x0002B; frequently used concepts in English is shown in <xref ref-type="fig" rid="F11">Figure 11</xref> (Wang and Valipour, <xref ref-type="bibr" rid="B76">2016</xref>; Valipour and Wang, <xref ref-type="bibr" rid="B28">2017</xref>; Wang et al., <xref ref-type="bibr" rid="B81">2017</xref>). It only takes the &#x003BA;<italic>C</italic> less than a minute to quantitatively acquire such scope of knowledge represented by a network of quantitative semantic relations, which would normally require several months by traditional qualitative ontology-extraction in forms of non-quantitative or subjective knowledge graphs without adopting rigorous IM underpinned by concept algebra (Wang, <xref ref-type="bibr" rid="B41">2010</xref>) and semantic algebra (Wang, <xref ref-type="bibr" rid="B48">2013</xref>).</p>
<fig id="F11" position="float">
<label>Figure 11</label>
<caption><p>Experiment on autonomous knowledge learning by &#x003BA;<italic>C</italic>.</p></caption>
<graphic mimetype="image" mime-subtype="tiff" xlink:href="fcomp-05-1152592-g0011.tif"/>
</fig>
<p>More significantly in the experiment, the accuracy of semantic analyses by &#x003BA;<italic>C</italic> has not only surpassed normal readers but also over performed expert linguists who composed typical English dictionaries, which are enabled by &#x003BA;<italic>C</italic>&#x00027;s rigorous and quantitative semantic cognition power. Applications of autonomous knowledge learning based on concept algebra and semantic algebra may refer to Wang (<xref ref-type="bibr" rid="B32">2007</xref>, <xref ref-type="bibr" rid="B49">2014a</xref>, <xref ref-type="bibr" rid="B53">2016c</xref>, <xref ref-type="bibr" rid="B54">2018</xref>), Wang et al. (<xref ref-type="bibr" rid="B75">2011</xref>).</p>
<p>The unpresented impact of &#x003BA;<italic>C</italic> on autonomous knowledge learning toward AIG, among other cognitive functions as shown in Section 3.2, is its capability to directly transfer learnt knowledge to peers based on the unified knowledge representation models (OAR) and manipulation mechanisms as shown in <xref ref-type="fig" rid="F4">Figures 4</xref>, <xref ref-type="fig" rid="F11">11</xref>. Therefore, &#x003BA;<italic>C</italic> may avoid the redundancy of human learning where similar knowledge must be repetitively relearned by individuals. Therefore, the direct shareability of machine knowledge learning results enabled by &#x003BA;<italic>C</italic> will be an indispensable intelligent platform for assisting human learning based on symbiotic knowledge bases. It will unleash the &#x003BA;<italic>C</italic> power to exponentially expand machine-learning for enabling downloadable knowledge and intelligence for a wide range of novel applications.</p>
<p>It is noteworthy through this joint work that contemporary intelligent mathematics has played an indispensable role in abstract science in general, and in the odyssey of intelligence science toward &#x003BA;<italic>C</italic> in particular. A wide range of applications of &#x003BA;<italic>C</italic> will be expected to demonstrate how &#x003BA;<italic>C</italic> will realize machine enables knowledge processing and autonomous intelligence generation, which would significantly change our sciences, engineering, and everyday life.</p></sec>
<sec id="s5">
<title>5. Conclusion</title>
<p>This work has presented a retrospective review and prospective outlook on <italic>cognitive computers</italic> (&#x003BA;<italic>C</italic>) inspired by the brain and powered by novel intelligent mathematics (IM). It has revealed the shift in the paradigm of computing theories and technologies underpinned by basic research in autonomous AI (AAI) driven by IM. It has been discovered that the structures, mechanisms, and inference engines of &#x003BA;<italic>C</italic>s are fundamentally different from those of the classical pre-programmed von Neumann computers and pre-trained neural networks, because both of them have been inadequately feasible for real-time and runtime autonomous intelligence generation that is not merely regressive data-driven according to basic research in brain and intelligence sciences. Powered by &#x003BA;<italic>C</italic> and IM, intelligence generation is no longer a gifted privilege of humans, because machine intelligence may surpass natural intelligence generation in more aspects according to the Layered Reference Model of the Brain (LRMB), via not only machine learning but also machine thinking, inference, and creativity.</p>
<p>This paper has formally elaborated the latest basic research of the I2CICC initiative in brain, intelligence, knowledge, and computer sciences underpinned by IM. The transdisciplinary studies have led to the emergence of &#x003BA;<italic>C</italic> for autonomous intelligence generation by none pre-trained and none pre-programmed AAI technologies. A set of novel theories and intelligent mathematical means has been created. The architectures and functions of &#x003BA;<italic>C</italic> for cognitive computing and autonomous intelligence generation have been elaborated, which are evidenced by experiments on autonomous knowledge learning by &#x003BA;<italic>C</italic>. The basic research and technical innovations will unleash &#x003BA;<italic>C</italic> to augment human intelligence in a pervasive scope and with an accelerating pace toward the next-generation of symbiotic human-robot societies.</p></sec>
<sec sec-type="author-contributions" id="s6">
<title>Author contributions</title>
<p>BW, WP, RB, KP, IR, and JL: concepts, related work, discussions, and reviews. CH: concepts and related work. JK: concepts, survey, related work, discussions, and reviews. All authors contributed to the article and approved the submitted version.</p></sec>
</body>
<back>
<sec sec-type="funding-information" id="s7">
<title>Funding</title>
<p>This work was supported in part by NSERC, DRDC, the IEEE Autonomous System Initiative (ASI), the IEEE CI TC-SW, IEEE SMC TC-BCS, the IEEE CS TC-LSC, and the Intelligent Mathematics Initiative of the International Institute of Cognitive Informatics and Cognitive Computing (I2CICC).</p>
</sec>
<ack><p>The authors would like to thank the reviewers and Professor Kaleem Siddiqi, EiC of FCS, for their professional insights and inspiring comments.</p>
</ack>
<sec sec-type="COI-statement" id="conf1">
<title>Conflict of interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec sec-type="disclaimer" id="s8">
<title>Publisher&#x00027;s note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
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