AUTHOR=Yang Jing , Xu Xiran , Zhang Jian , Que Kehua TITLE=The effect of moisture conditions and canal morphologies on the filling quality of iRoot SP with single-cone technique in root canals: an ex-vivo study JOURNAL=Frontiers in Dental Medicine VOLUME=Volume 6 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/dental-medicine/articles/10.3389/fdmed.2025.1523297 DOI=10.3389/fdmed.2025.1523297 ISSN=2673-4915 ABSTRACT=ObjectiveThe purpose of this study was to investigate the effects of intraradicular moisture conditions and canal morphologies on the filling quality of iRoot SP with single-cone technique in root canals.Materials and methodsEighty-four human single-rooted premolars root canals were pair-matched with similar root canal volumes, aspect ratio (AR) curve shapes, and 3D models after micro-computed tomography (micro-CT) scanning to establish baseline consistency. Root canals were then prepared and assigned to 4 experimental groups with respect to the moisture condition tested: (1) Paper point normal drying (2) ROKEO drying (3) Paper point preliminary drying (4) Wet, followed by filling with iRoot SP single-cone technique. The effects of moisture conditions on root filling quality were studied by calculating the volume percentage of voids through micro-CT scanning and the number and score of voids under dental operating microscope (DOM) observation of the cross-sectional slices. Then classified different cross-sectional anatomical morphologies of the root canals based on the AR value and their impact on the volume percentage of voids after root canal filling were evaluated.ResultsUnified the sample baseline through micro-CT pair-matching, both micro-CT and DOM provided complementary information showed that paper point normal drying and ROEKO drying displayed the lowest voids in terms of volume, number and score (P < 0.05) after filling with iRoot SP single-cone technique in root canals. Further analysis revealed that the voids in different segments of the root canal under four moisture conditions ranked as coronal 1/3 > middle 1/3 > apical 1/3 (P < 0.05). In addition, the cross-sectional AR value of the root canal was positively correlated with the volume of voids within each moisture condition(P < 0.05).ConclusionThe intraradicular moisture conditions and cross-sectional anatomical morphology had significant effect on the filling quality of iRoot SP with single-cone technique.