AUTHOR=Quaresma Cláudia , Lopes Barbara , Jacinto Jorge , Robalo Tiago , Matos Mariana , Quintão Carla TITLE=OrthoRehab: Development of a New Methodology for the Comparison Study Between Different Types of Ankle–Foot Orthoses in Foot Dysfunction JOURNAL=Frontiers in Digital Health VOLUME=Volume 2 - 2020 YEAR=2021 URL=https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2020.589521 DOI=10.3389/fdgth.2020.589521 ISSN=2673-253X ABSTRACT=Foot dysfunction is one of the most likely consequences of rheumatoid arthritis and stroke. It is characterised by severe changes in the gait pattern due to a significant increase in the plantar flexion. Some of these dysfunctions can be compensated by using ankle-foot orthosis. However, the clinical decisions about which orthosis best suits the patient needs is a real problem for physicians/therapists. Purpose The main goal of this paper is to present a quantitative support tool that can assist the physicians/therapists in deciding which orthosis is most suitable for each subject. Methodology In order to achieve this goal, a platform namely OrthoRehab was developed, and it was tested in three conditions: without any orthosis and with two different dynamic ankle-foot orthoses - B and A. The data was acquired in the Gait Laboratory of Rehabilitation Medicine Center of A. using a VICON NEXUS 1.8.5® motion capture system that allows the capturing of kinematic and kinetic data. Results The results reveal that OrthoRehab is a user-friendly, easy to apply tool which analyses very relevant data for the clinical staff. Conclusion The developed decision support tool, OrthoRehab, offers a quantitative analysis and provides insight to which orthosis achieved the best performance in comparison with the patient's gait pattern with no orthosis.