AUTHOR=Babel Aditi , Taneja Richi , Mondello Malvestiti Franco , Monaco Alessandro , Donde Shaantanu TITLE=Artificial Intelligence Solutions to Increase Medication Adherence in Patients With Non-communicable Diseases JOURNAL=Frontiers in Digital Health VOLUME=Volume 3 - 2021 YEAR=2021 URL=https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2021.669869 DOI=10.3389/fdgth.2021.669869 ISSN=2673-253X ABSTRACT=The aim of this scoping review is to describe: 1) studies on Artificial Intelligence (AI) tools that can be used to measure and increase medication adherence in patients with noncommunicable diseases (NCDs); 2) the benefits of using AI for these purposes; 3) challenges of the use of AI in health care and; 4) priorities for future research. We discuss current AI technologies including mobile phone applications, reminder systems, tools for patient empowerment, instruments that can be used in integrated care, and machine learning. The use of AI may be key to understanding the complex interplay of factors that underly medication nonadherence in NCD patients. AI-assisted interventions to improve communication between patients and physicians, monitor drug consumption, empower patients and, ultimately, increase adherence levels may lead to better clinical outcomes and increase quality of life in NCD patients. However, the use of AI in health care is challenged by numerous factors; the characteristics of users can impact the effectiveness of an AI tool, which may lead to further inequalities in health care, and there may be concerns that it could depersonalize medicine. The success and widespread use of AI technologies will depend on data storage capacity, processing power, and other infrastructure capacities within health care systems. Research is needed to evaluate the effectiveness of AI solutions in different patient groups and establish the barriers to widespread adoption, especially in light of the COVID-19 pandemic, which has led to a rapid increase in the use and development of digital health technologies.