AUTHOR=Russ Philipp , Mross Peter M. , Kräling Gunter , Lechner Fabian , Eldakar Mohamed , Schlicker Nadine , Bedenbender Simon , Brouwer Sylvain , Zantvoort Kirsten , Jerrentrup Andreas , Grgic Ivica , Hirsch Martin C. TITLE=Feasibility of a multimodal AI-based clinical assessment platform in emergency care: an exploratory pilot study JOURNAL=Frontiers in Digital Health VOLUME=Volume 7 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1657583 DOI=10.3389/fdgth.2025.1657583 ISSN=2673-253X ABSTRACT=BackgroundOvercrowding in emergency departments (EDs) is a key challenge in modern healthcare, affecting not only patient and staff comfort but also mortality rates and quality of care. Artificial intelligence (AI) offers the potential to optimize ED workflows by automating processes such as triage, history-taking and documentation. To explore a potential approach to overcrowding, we developed a multimodal and modular AI-based platform that integrates these functions into a single system. This exploratory pilot study investigated the feasibility of implementing the platform, focusing particularly on usability and patient trust in the system.MethodsAmbulatory patients triaged as non-urgent at the Marburg University Hospital ED were recruited. After providing written consent, they underwent an AI-supported initial assessment, including vital sign monitoring, automated triage, suspected diagnosis and automatic report generation. Participants then completed validated questionnaires on usability, Trust in Automation (TiA), and a supplementary self-developed survey.ResultsA total of 20 patients were enrolled (70% female, 30% male; mean age 45.1 years), with an average interaction time of 10.6 min. The majority (80%) reported feeling safe, satisfied, and willing to recommend the system, while areas for improvement were identified regarding patient inclusion in decision-making and the perceived quality of information received. Usability was rated as excellent, with a mean System Usability Scale (SUS) score of 90.6. Although familiarity with the system was low, trust-related measures assessed using the TiA questionnaire were generally high.ConclusionThis exploratory pilot study demonstrates the feasibility and user acceptance of a multimodal AI platform in an ED setting. The system achieved high patient satisfaction, excellent usability, and a generally high level of trust. While these findings are limited to feasibility and perception, they indicate that such systems could serve as a basis for multicenter studies that directly evaluate impacts on triage accuracy, patient engagement, and clinical efficiency.