The Brain-targeted Drug Delivery section of Frontiers in Drug Delivery publishes high-quality reports on basic, translational and clinical research that focuses on the increased and specific delivery of drugs and biopharmacons to the Central Nervous System.Read More
The Brain-targeted Drug Delivery section of Frontiers in Drug Delivery publishes high-quality reports on basic, translational and clinical research that focuses on the increased and specific delivery of drugs and biopharmacons to the Central Nervous System (CNS). The pharmacological treatment of neurological disorders including stroke, neurodegenerative diseases, epilepsy and brain tumors is hindered by the defence systems of the CNS barriers. The key to solve this problem is the better understanding of the transport systems and pathways of the blood-brain barrier in health as well as in diseases and the discovery of novel drug delivery platforms and methods specifically targeting them. The advances in this scientific field will have huge impact on the development of systems to increase drug delivery to the brain leading to improved therapy of CNS diseases.
Areas covered by this interdisciplinary section include, but are not limited to:
Drug transport systems at the brain barriers
Influx and efflux transporters at the brain barriers in diseases
Receptor-mediated transport across the blood-brain barrier
Endo- and transcytotic pathways at the blood-brain barrier
Brain-targeted nanodelivery systems
Extracellular vesicles as platforms for brain delivery
Peptides and small molecule ligands as brain targeting vectors
Organ-on-a-chip models to study drug targeting to brain
All studies must contribute insights into drug delivery to the CNS in physiological or in patholigical conditions.
Indexed in: Google Scholar, CrossRef, CLOCKSS, OpenAIRE
Brain-Targeted Drug Delivery welcomes submissions of the following article types: Brief Research Report, Case Report, Clinical Trial, Community Case Study, Data Report, Editorial, General Commentary, Hypothesis and Theory, Methods, Mini Review, Opinion, Original Research, Perspective, Policy and Practice Reviews, Policy Brief, Protocols, Review, Specialty Grand Challenge, Systematic Review and Technology and Code.
All manuscripts must be submitted directly to the section Brain-Targeted Drug Delivery, where they are peer-reviewed by the Associate and Review Editors of the specialty section.
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