Original Research

Published on 12 Dec 2022

In silico mapping of the dynamic interactions and structure-activity relationship of flavonoid compounds against the immune checkpoint programmed-cell death 1 pathway

in In silico Methods and Artificial Intelligence for Drug Discovery

Geraldo Rodrigues Sartori
Aline de Oliveira Albuquerque
Andrielly Henriques Santos-Costa
Luca Milério Andrade
Diego da Silva Almeida
Eduardo Menezes Gaieta
Jean Vieira Sampaio
Vitória Taiana de Melo Lima Albuquerque
João Hermínio Martins Da Silva

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1032587

2,501 views
1 citation

Mini Review

Published on 08 Dec 2022

Zingiber officinale (Ginger) as a treatment for inflammatory bowel disease: A review of current literature

in Anti-inflammatory and Immunomodulating Agents

Fatemeh Sadeghi Poor Ranjbar
Fatemeh Mohammadyari
Atharzahra Omidvar
Farhad Nikzad
Nooria Doozandeh Nargesi
Majid Varmazyar
Soroush Dehghankar
Fatemeh Vosoughian
Sepehr Olangian-Tehrani
Sepehr Nanbakhsh

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1043617

4,722 views
4 citations

Review

Published on 07 Dec 2022

The landscape of nature-derived antimalarials-potential of marine natural products in countering the evolving Plasmodium

in Anti-Infective Agents

Cherish Prashar
Narsinh Thakur
Soumyananda Chakraborti
Syed Shah Areeb Hussain
Kapil Vashisht
Kailash C. Pandey

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1065231

1,830 views
4 citations

Review

Published on 06 Dec 2022

Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents

in Anti-Cancer Drugs

Krishna N. Mishra
Harish C. Upadhyay

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1072448

3,161 views
6 citations

Original Research

Published on 29 Nov 2022

ASK120067 (limertinib) exerts pre-clinical anti-tumor activity by inhibiting EGFR exon20 insertion

in Anti-Cancer Drugs

Tao Zhang
Fang Feng
Linjiang Tong
Shingpan Chan
Yi Chen
Yan Li
Peiran Song
Yingqiang Liu
Gang Bai
Mengzhen Lai

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1050687

1,544 views

Mini Review

Published on 03 Nov 2022

Oxidized phospholipids are biomarkers, drug targets, and drug leads

in Cardiovascular and Hematologic Drugs

Olga V. Oskolkova
Anna A. Birukova
Konstantin G. Birukov
Valery N. Bochkov

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1043708

1,989 views
3 citations

Review

Published on 02 Nov 2022

Artificial intelligence for antiviral drug discovery in low resourced settings: A perspective

in In silico Methods and Artificial Intelligence for Drug Discovery

Cyril T. Namba-Nzanguim
Gemma Turon
Conrad V. Simoben
Ian Tietjen
Luis J. Montaner
Simon M. N. Efange
Miquel Duran-Frigola
Fidele Ntie-Kang

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1013285

4,008 views
5 citations

Systematic Review

Published on 25 Oct 2022

Characterization of KLH-driven immune responses in clinical studies: A systematic review

in Anti-inflammatory and Immunomodulating Agents

Mahdi Saghari
Manon A. A. Jansen
Hendrika W. Grievink
Robert Rissmann
Matthijs Moerland

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.992087

4,701 views
1 citation

Original Research

Published on 25 Oct 2022

Network pharmacology and molecular docking to explore Siraitia grosvenorii’s potential mechanism in preventing and treating proliferative diabetic retinopathy

in Anti-inflammatory and Immunomodulating Agents

Yehong Zhou
Fuxing Shu
Surendra Sarsaiya
Hu Jiang
Chengyan Jiang
Tingnian Qu
Ruixia Wang

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1038224

1,373 views
1 citation

Original Research

Published on 21 Oct 2022

A machine learning-based virtual screening for natural compounds capable of inhibiting the HIV-1 integrase

in Anti-Infective Agents

Lucas A. Machado
Eduardo Krempser
Ana Carolina Ramos Guimarães

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.954911

3,510 views
6 citations

Review

Published on 21 Oct 2022

Nine receptors and binding proteins, four drugs, and one woman: Historical and personal perspectives

in Anti-inflammatory and Immunomodulating Agents

Daniela Novick

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1001487

1,931 views
3 citations

Original Research

Published on 20 Oct 2022

From drugs to targets: Reverse engineering the virtual screening process on a proteomic scale

in Anti-Infective Agents

Gustavo Schottlender
Juan Manuel Prieto
Miranda Clara Palumbo
Florencia A. Castello
Federico Serral
Ezequiel J. Sosa
Adrián G. Turjanski
Marcelo A. Martì
Darío Fernández Do Porto

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.969983

2,839 views
4 citations

Original Research

Published on 18 Oct 2022

Plasma brain injury markers are associated with volume status but not muscle health in heart failure patients

in Cardiovascular and Hematologic Drugs

Shouri Lahiri
Mitra Mastali
Jennifer E. Van Eyk
Tara C. Hitzeman
Catherine Bresee
Koen Raedschelders
Patrick D. Lyden
Roberta A. Gottlieb
James C. Fang
Robin M. Shaw

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1042737

1,198 views
1 citation

Mini Review

Published on 12 Oct 2022

Current and potential therapeutic strategies for transthyretin cardiac amyloidosis

in Cardiovascular and Hematologic Drugs

Marcus A. C. Williams
Bairavi Shankar
Joban Vaishnav
Mark J. Ranek

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1015545

3,964 views
2 citations

Review

Published on 12 Oct 2022

Chemically induced phenotypes during the blood stage development of Plasmodium falciparum as indicators of the drug mode of action

in Anti-Infective Agents

Keerthy Reghunandanan
Rajesh Chandramohanadas

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.920850

2,392 views
1 citation

Original Research

Published on 11 Oct 2022

Artificial intelligence platform, RADR®, aids in the discovery of DNA damaging agent for the ultra-rare cancer Atypical Teratoid Rhabdoid Tumors

in In silico Methods and Artificial Intelligence for Drug Discovery

Joseph McDermott
Drew Sturtevant
Umesh Kathad
Sudhir Varma
Jianli Zhou
Aditya Kulkarni
Neha Biyani
Caleb Schimke
William C. Reinhold
Fathi Elloumi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2022.1033395

3,093 views
3 citations

Navigation group

Articles

In silico mapping of the dynamic interactions and structure-activity relationship of flavonoid compounds against the immune checkpoint programmed-cell death 1 pathway

Zingiber officinale (Ginger) as a treatment for inflammatory bowel disease: A review of current literature

The landscape of nature-derived antimalarials-potential of marine natural products in countering the evolving Plasmodium

Coumarin-1,2,3-triazole hybrids as leading-edge anticancer agents

ASK120067 (limertinib) exerts pre-clinical anti-tumor activity by inhibiting EGFR exon20 insertion

Oxidized phospholipids are biomarkers, drug targets, and drug leads

Artificial intelligence for antiviral drug discovery in low resourced settings: A perspective

Characterization of KLH-driven immune responses in clinical studies: A systematic review

Network pharmacology and molecular docking to explore Siraitia grosvenorii’s potential mechanism in preventing and treating proliferative diabetic retinopathy

A machine learning-based virtual screening for natural compounds capable of inhibiting the HIV-1 integrase

Nine receptors and binding proteins, four drugs, and one woman: Historical and personal perspectives

From drugs to targets: Reverse engineering the virtual screening process on a proteomic scale

Plasma brain injury markers are associated with volume status but not muscle health in heart failure patients

Current and potential therapeutic strategies for transthyretin cardiac amyloidosis

Chemically induced phenotypes during the blood stage development of Plasmodium falciparum as indicators of the drug mode of action

Artificial intelligence platform, RADR®, aids in the discovery of DNA damaging agent for the ultra-rare cancer Atypical Teratoid Rhabdoid Tumors