AUTHOR=Ćeriman Krstić Vesna , Gajić Milija , Djukanović Leonida , Jovanović Dragana 

TITLE=Corticosteroids in lung cancer

JOURNAL=Frontiers in Drug Safety and Regulation

VOLUME=Volume 5 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/drug-safety-and-regulation/articles/10.3389/fdsfr.2025.1528468

DOI=10.3389/fdsfr.2025.1528468

ISSN=2674-0869

ABSTRACT=Despite significant advances in lung cancer treatment, patients with this disease still present with multiple symptoms that are very hard to control. Corticosteroids are widely used in patients with lung cancer, but without clear evidence for their efficacy. Thus, corticosteroids have been used for the treatment of conditions arising due to the tumor itself, adverse effects of the applied specific therapy and symptom palliation. In this review we are going to summarize clinical indications for corticosteroid use in patients with lung cancer: malignant airway obstruction, superior vena cava syndrome, brain metastases, treatment-related adverse events, anorexia and cachexia, fatigue, dyspnea, nausea and vomiting, spinal cord compression, and pain.