REVIEW article

Front. Electron.

Sec. Integrated Circuits and VLSI

CMOS-Based Physically Unclonable Functions: Guidelines on Properties and Design

  • University of Guelph, Guelph, Canada

The final, formatted version of the article will be published soon.

Abstract

Physically unclonable functions (PUFs) based on CMOS technology have become essential security primitives for ASIC identification and authentication. Linking intrinsic transistor-level variations to the randomness of responses generated at the PUF system level is a fundamental challenge for ASIC designers aiming to integrate CMOS-based PUFs into electronic chips. This paper discusses the key intrinsic fabrication variations in bulk MOSFETs. It presents guidelines for leveraging these variations to obtain measurable yet physically unclonable and mathematically unmodelable unique and reliable imprints for ASICs. The study reviews various PUF architectures, their practical applications, and the challenges associated with their implementation. The article also presents a comprehensive yet easy-to-follow mathematical framework to characterize PUF metrics and testing methodologies. This review aims to provide an accessible introduction for novel CMOS-based PUF designers by addressing the primary sources of intrinsic variations in planar transistors and offering recommendations at the schematic, layout, masking, and fabrication levels. The review article also touches on the early types of electronic PUFs, parameters, applications, and limitations. This study provides an accessible tool for these vast topics while adhering to the publication's scope and size constraints.

Summary

Keywords

ASIC, CMOS, Hardware security, MOSFET, PUF

Received

22 December 2025

Accepted

30 April 2026

Copyright

© 2026 Y. Kamal and Gregori. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Kamal Y. Kamal

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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