AUTHOR=Caron Juliette , Domenger Dorothée , Dhulster Pascal , Ravallec Rozenn , Cudennec Benoit 

TITLE=Protein Digestion-Derived Peptides and the Peripheral Regulation of Food Intake

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 8 - 2017

YEAR=2017

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2017.00085

DOI=10.3389/fendo.2017.00085

ISSN=1664-2392

ABSTRACT=The gut plays a central role in energy homeostasis. Food intake regulation strongly relies on the gut-brain axis and numerous studies have pointed out the significant role played by gut hormones released from enteroendocrine cells. It is well known that digestive products of dietary protein possess a high satiating effect compared to carbohydrates and fat. Nevertheless, the processes occurring in the gut during protein digestion involved in the short-term regulation of food intake are still not totally unraveled. This review provides a concise overview of the current data concerning the implication of food-derived peptides in the peripheral regulation of food intake with a focus on the gut hormones CCK and GLP-1 regulation and the relationship with some aspects of glucose homeostasis.