AUTHOR=Liu Yaoxia , Li Jianwei , Liu Hui , Yang Han , Qiao Jingtao , Wei Tao , Wang Tao , Yu Yerong 

TITLE=Spontaneous Remission After a Hypercalcemic Crisis Caused by an Intracystic Hemorrhage of Bilateral Parathyroid Adenomas: A Case Report and Literature Review

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2021.766234

DOI=10.3389/fendo.2021.766234

ISSN=1664-2392

ABSTRACT=Background: Hyperparathyroidism is a common cause of hypercalcemia; however, spontaneous remission after a hypercalcemic crisis caused by an intracystic hemorrhage of parathyroid adenomas is very rare. The question, then, is “What is the best choice in such cases--conservative treatment or surgery?”
Method: A 47-year-old male patient with primary hyperparathyroidism and a hypercalcemic crisis is reported. Hypercalcemia was spontaneously relieved thereafter. The post-operative pathology results indicated an intracystic hemorrhage of bilateral parathyroid adenomas. 
Results: After the case report, a literature review is also included to summarize the clinical features of this patient and to provide special reference for clinical diagnosis and treatment of similar cases.  
Conclusions: The choice of surgical timing for such cases can be made based on the comprehensive consideration of clinical symptoms and changes in parathyroid function.