AUTHOR=Chen Lingzhi , Liu Yiyuan , Cai Jiehui , Ji Zeqi , Zou Juan , Chen Yaokun , Wu Jinyao , Zheng Daitian , Zheng Jiehua , Chen Yexi , Li Zhiyang 

TITLE=Global Trends in Research of Androgen Receptor Associated With Breast Cancer From 2011 to 2020: A Scientometric Analysis

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.887612

DOI=10.3389/fendo.2022.887612

ISSN=1664-2392

ABSTRACT=Recently androgen receptor has been found as a potential prognostic index and therapeutic target for breast cancer. To reveal the current research status and hotspots in this area, we analyzed the characters of related publications from 2011 to 2020. All related publications from 2011 to 2020 were retrieved from Web of Science. Biblioshiny, VOSviewer and CiteSpace V were applied to obtain the information of annual publications and citations, the highest yield countries and authors, influential journals and articles, as well as hot keywords. In total, 2118 documents including 1584 original articles and 534 reviews were retrieved. Annual publications output was rich from 2014 to 2018, reaching the top in 2017. A systematic review written by Lehman, BD et al.in 2011 was the most-cited document and references. The United States was the leading country with the maximum number of publications, citations, link strengths with other countries. The journal publishing the most was Oncotarget. Lehmann BD was the author who had highest link strengths with other authors. The most highlighted keywords were “androgen receptor” (n=1209), “breast-cancer” (n=690), “expression” (n=545), “breast cancer” (n=410), “prostate-cancer” (n=290) and so on, revealing the trend from molecular mechanism level to therapeutic use level. Androgen receptor plays a significant role in the development of breast cancers, whereas its therapeutic value seems to be controversial and need further studying. With the help of a scientometric analysis in this field, researchers can clarify the current research status and hot spots worth to fully explore.