AUTHOR=Dong Xiaoqian , Li Ying , Xie Jianfei , Li Lijun , Wan Ziyu , Kang Yue , Luo Yating , Wang Jiangang , Duan Yinglong , Ding Siqing , Cheng Andy SK TITLE=The prevalence of thyroid nodules and its factors among Chinese adult women: A cross-sectional study JOURNAL=Frontiers in Endocrinology VOLUME=Volume 13 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.967380 DOI=10.3389/fendo.2022.967380 ISSN=1664-2392 ABSTRACT=Objective: To determine the prevalence of thyroid nodules in Chinese adult women and the impact of lifestyle and metabolic syndrome on thyroid nodules as well as their predictors. Methods: We conducted a cross-sectional study in the tertiary hospital from 2017 to 2019. Included participants underwent thyroid color Doppler ultrasonography, lipids examination, and dietary evaluation. Results: Totally, 933 thyroid nodules patients and 1,851 individuals without thyroid nodules were included. The prevalence of thyroid nodules was 33.3%. Women in 50-59 years (OR: 1.746, 95% CI [1.356-2.249]), older than 60 (2.147 [1.540-2.993]) and occupations with mainly manual work (1.780 [1.367-2.317]) were risk factors for thyroid nodules, while moderate dietary diversity (0.624 [0.476-0.817]) and normal triglycerides level (0.739 [0.604-0.905]) were protective factors. Conclusion: Women over 50 and those whose jobs are mainly manual should enhance screening, follow-up and health management of thyroid nodules. Higher dietary diversity is protective measures against thyroid nodules for adult women and should consider dietary balance and the food varieties, not just increased quantities.