AUTHOR=Zhao Yang , Lu Xunhao , Wang Yanghua , Cheng Yiyi , He Qiao , Qin Rongqi , Li Wenrui , Liu Haizhou , Liu Yuanfang 

TITLE=Peripheral blood lipid and liver and kidney function test results in long-term night shift nurses: a cross-sectional study in South China

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1237467

DOI=10.3389/fendo.2023.1237467

ISSN=1664-2392

ABSTRACT=Purpose: This study aimed to elucidate the effects of long-term day and night shifts on liver function and lipid metabolism in a group of nurses.This cross-sectional study in December 2019 was based on a group of nurses.One thousand two hundred fifty-three physically healthy caregivers were included, including 1231 women and 22 men. 886 nurses had long-term shift work(work (working in a rotating system for >1 year). The receiver operating characteristic (ROC) curve and Logistic regression analyses were used to evaluate factors related to longterm shift work.We observed differences in liver and kidney indicators between the non-night and night shift groups. The ROC curve revealed that CHO (AUC: 62.4%), LDLC (AUC: 62%), and GLUO (AUC: 61.5%) were more related to the night shift. Logistic regression analysis showed night shift work was associated significantly with CREA