AUTHOR=Jammah Anwar Ali , AlSadhan Ibrahim Mohammed , Alyusuf Ebtihal Y. , Alajmi Mubarak , Alhamoudi Abdullah , Al-Sofiani Mohammed E. 

TITLE=The American Thyroid Association risk stratification and long-term outcomes of differentiated thyroid cancer: a 20-year follow-up of patients in Saudi Arabia

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1256232

DOI=10.3389/fendo.2023.1256232

ISSN=1664-2392

ABSTRACT=Background: Studies have reported differing factors associated with poor outcomes in patients with differentiated thyroid cancer (DTC). We aimed to describe our 20 years' experience on the management of thyroid cancer {TC}DTC and identify predictors of treatment outcomes.We conducted a retrospective review of medical records of patients with DTC seen in the Thyroid Center (TC) at King Saud University Medical City (KSUMC) in Riyadh, Saudi Arabia between the years 2000 and 2020. Demographic and clinical data includingThe tumor size, lymphovascular invasion, and obesity are strong predictors of a worse response to therapy among patients with DTC. Patients with obesity should be carefully followed up regardless of their risk stratification in light of the recent compelling evidence associating obesity to thyroid cancer and its higher risk of a worse disease outcome.ATA risk stratification is well correlated with patient long-term outcomes.