AUTHOR=Yan Xianlei , Li Jinwei , Zhang Yang , Liang Cong , Liang Pengcheng , Li Tao , Liu Quan , Hui Xuhui 

TITLE=Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 14 - 2023

YEAR=2023

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1292944

DOI=10.3389/fendo.2023.1292944

ISSN=1664-2392

ABSTRACT=Glioma is a type of brain tumor closely related to abnormal cell metabolism. Firstly, multiple combinatorial sequencing studies have revealed this relationship. Genomic studies have identified gene mutations and gene expression disorders related to the development of gliomas, which affect cell metabolic pathways. In addition, transcriptome studies have revealed the genes and regulatory networks that regulate cell metabolism in glioma tissues. Metabonomics studies have shown that the metabolic pathway of glioma cells has changed, indicating their distinct energy and nutritional requirements. This paper focuses on the retrospective analysis of multiple