AUTHOR=Zhang Shilong , Zhang Xindan , Wang Haipeng , Fan Wenyu , Ma Xingli , Song Suhang , Zhang Beibei TITLE=Factors associated with psychological insulin resistance among patients with type 2 diabetes in China JOURNAL=Frontiers in Endocrinology VOLUME=Volume 15 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1368132 DOI=10.3389/fendo.2024.1368132 ISSN=1664-2392 ABSTRACT=Objective: This study aimed to understand the psychological insulin resistance status among Chinese patients with type 2 diabetes and investigate its associated factors in Chinese patients with type 2 diabetes. Methods: A multi-stage stratified random sampling was performed to randomly select patients with type 2 diabetes from the eastern, central and western regions in Shandong Province, China, and 660 valid questionnaires were collected. Psychological insulin resistance was assessed by the scale of My Opinion on Insulin (MOI). Factors associated with psychological insulin resistance were examined in a binary logistic model. Results: Four-fifths of the type 2 diabetes patients (82.1%) had psychological insulin resistance. Being female (OR= 1.770, 95%CI:1.063-2.950, p<0.05), monthly income greater than 4000 Renminbi (about 1540 $) or more (OR= 0.444, 95%CI:0.216-0.915, p<0.05), living with type 2 diabetes for 11 years or more (OR= 0.387, 95%CI:0.238-0.630, p<0.05), self-rated poor health (OR= 1.706, 95%CI:1.092-2.664, p<0.05), and moderate discrimination against type 2 diabetes (OR= 1.924, 95%CI:1.166-3.175, p<0.05) were associated with psychological insulin resistance. Conclusions: The prevalence of psychological insulin resistance among Chinese patients with type 2 diabetes is relatively high. Approaches are needed to address the issue of psychological insulin resistance of type 2 diabetes.