AUTHOR=Resnick Ortal , Bril Fernando , Beauchamp Giovanna TITLE=Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? JOURNAL=Frontiers in Endocrinology VOLUME=Volume 15 - 2024 YEAR=2025 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1520313 DOI=10.3389/fendo.2024.1520313 ISSN=1664-2392 ABSTRACT=This mini review explores the increasing prevalence of obesity in type 1 diabetes (T1D) and the challenges patients face in achieving optimal glycemic control with current treatments. It discusses the evidence supporting the use of glucagon-like peptide-1 receptor agonists (GLP-1RA) as potential adjunctive therapy in T1D to reduce weight and improve insulin resistance. Potential benefits need to be weighed against the risk of hypoglycemia and lack of long-term data.