AUTHOR=Orszulak Dominika , Niziński Kacper , Matonóg Aleksandra , Zięba-Domalik Maja , Stojko Rafał , Drosdzol-Cop Agnieszka 

TITLE=Adipokines as biochemical marker of polycystic ovary syndrome in adolescents – review

JOURNAL=Frontiers in Endocrinology

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1475465

DOI=10.3389/fendo.2025.1475465

ISSN=1664-2392

ABSTRACT=Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting approximately 10% of adolescent women. According to literature data, in the case of coexistence of obesity and PCOS, menstrual cycle disorders are much more common. One of the probable reasons is the activity of adipose tissue, which secretes many types of adipokines that may have a negative impact on hormonal and metabolic functions. This article reviews the literature on the role of adipokines in the etiopathogenesis of PCOS in adolescent girls. The literature base consisted of published articles - clinical trials, meta-analyses, reviews and systematic reviews. The databases - PubMed, ScienceDirect, EMBASE were searched.