Frontiers in Endocrinology | Translational and Clinical Endocrinology

Study Protocol

Published on 10 Feb 2026

Independent effects of exercise intensity on hepatic fat reduction in adults with metabolic dysfunction–associated steatotic liver disease: a randomized controlled trial protocol

in Translational and Clinical Endocrinology

Wei Huang
Yifei He
Rong Chen
Cuilan Huo
Yijun Xie
Yanyu Lin
Tian Wang
Xiangdi Dai
Junyu Wang
Weiqi Ruan

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1711420

329 views

Original Research

Published on 09 Feb 2026

Testosterone plus lifestyle therapy improves skeletal muscle glycolysis in older men with obesity and hypogonadism

in Translational and Clinical Endocrinology

Viola Viola
Marlene Aguilar
Maria Liza Duremdes Nava
Alessandra Celli
Reina Armamento-Villareal
Yoann Barnouin
Nicola Napoli
Nagireeddy Putluri
Clifford Qualls
Dennis T. Villareal

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1719749

893 views

Systematic Review

Accepted on 06 Feb 2026

The effectiveness of digital health interventions on anthropometric and healthy behaviour in women with polycystic ovarian syndrome: A Systematic Review with Meta-analysis

in Translational and Clinical Endocrinology

huifang zeng
zhen dou
yinuo zhang
chuchu wang
Tian Xia
jing xu

Frontiers in Endocrinology

101 views

Correction

Published on 05 Feb 2026

Correction: From traditional metabolic markers to ensemble learning: comparative application of machine learning models for predicting NAFLD risk in adolescents

in Translational and Clinical Endocrinology

Chenming Zhang
Bin Niu
Rong Wang
Liaoyun Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2026.1763989

330 views

Original Research

Accepted on 29 Jan 2026

Functional analysis from ex-vivo characterization of LDLR exon 13-15 duplication associated to Familial Hypercholesterolemia

in Translational and Clinical Endocrinology

Catalina Martínez
Carolina Alarcón
Andrea Cid
Noemí Vilches
Claudia Radojkovic
Enrique Guzmán-Gutiérrez
Katia Saez
Rodrigo Alonso
Andrea Sanchez

Frontiers in Endocrinology

132 views

Original Research

Published on 19 Jan 2026

Neutrophil percentage-to-albumin ratio as a novel hematologic biomarker for predicting arteriogenic erectile dysfunction

in Translational and Clinical Endocrinology

Yangyang Mei
Guoyang Zhang
Yu Liu
Yiming Chen
Renfang Xu
Hao Lu
Hui Gao
Xianchao Sun
Wei Zhang
Xingliang Feng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1729618

700 views

Study Protocol

Accepted on 16 Jan 2026

Whole-body vibration training on functional capacity, vascular function, and glycemic control in type 2 diabetes individuals with peripheral arterial disease: protocol for a randomized clinical trial

in Translational and Clinical Endocrinology

Silmara Gusso
Sothida Nantakool
Busaba Chuatrakoon
José Guilherme Behrensdorf Derraik

Frontiers in Endocrinology

204 views

Original Research

Published on 12 Jan 2026

Remnant cholesterol: an independent, dose-dependent risk factor for hyperuricemia in a normolipidemic chinese population

in Translational and Clinical Endocrinology

Huali Xiong
Fengxun Ma

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1718817

804 views

Original Research

Published on 09 Jan 2026

Continuous auricular acupuncture and daytime intermittent electroacupuncture as a complementary therapeutic improve glycemic variability and stability under Continuous Glycemic Monitoring System in hospitalized diabetic patients

in Translational and Clinical Endocrinology

Jianlan Jin
Song Wen
Haiyan Liu
Lijiao Chen
Yishu Ren
Min Gong
Xinlu Yuan
Jiyu Li
Ligang Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1716837

1,215 views

Original Research

Published on 05 Jan 2026

Residual cholesterol is independently associated with arteriogenic erectile dysfunction: results from a multi-institutional study

in Translational and Clinical Endocrinology

Yangyang Mei
Yu Liu
Guoyang Zhang
Yiming Chen
Wei Xia
Mingran Zhang
Renfang Xu
Wei Zhang
Xingliang Feng
Qianfeng Zhuang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1715619

782 views

Mini Review

Published on 05 Jan 2026

Research progress in precision medicine for type 2 diabetes based on the GLP-1

in Translational and Clinical Endocrinology

Sangui Wang
Chenrong Yuan
Haifeng Wang
Xiyin Ye
Shun Ruan
Li Yi
Wanyong Yang
Zhi Wang
Ni Wang
Jiahao Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1721842

1,326 views

Review

Published on 19 Dec 2025

Research progress on multidimensional intervention strategies for hyperuricemia: Western medicine, Traditional Chinese Medicine, and emerging therapies

in Translational and Clinical Endocrinology

Xinze Li
Zilong Chen
Yanzhao Zhang
Chunyang Fan
Lulu Chen
Xiangman Xu
Jianying Chang
Wei Qiang
Hongwei Jiang
Chuanxin Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1722245

2,464 views

Original Research

Published on 18 Dec 2025

Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET

in Translational and Clinical Endocrinology

Seyed Faraz Nejati
Faranak Ebrahimian Sadabad
Rui Ren
Yuan Huang
Jason Bini

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1724340

1,488 views

Original Research

Published on 09 Dec 2025

Extracellular vesicle miR-425-5p promotes visceral fat reduction via DACT1 suppression in SGLT2i-treated diabetes

in Translational and Clinical Endocrinology

Jae-Hyung Park
Thi Nhi Nguyen
Hye Min Shim
Yun-Ui Bae
Gyeong Im Yu
Junho Kang
Eun Yeong Ha
Hochan Cho

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1725625

1,195 views

Original Research

Published on 01 Dec 2025

Risks of pelvic inflammatory disease and bacterial vaginosis in adenomyosis patients using levonorgestrel intrauterine device or oral norethindrone

in Translational and Clinical Endocrinology

Szu-Yun Niu
Yu-Chiao Yi
Yu-Hsiang Shih
Jenn-Jhy Tseng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1703310

1,487 views

Original Research

Published on 26 Nov 2025

Accurate screening of patients with diabetes based on physical examination: pancreas imaging features from chest CT and laboratory data

in Translational and Clinical Endocrinology

Jixing Yi
Jiarun Lin
Qing Feng
Zhou Huang
Shu Li
Bumin Liang
Haohua Wu
Haiwei Yan
Eqing Yang
Jiaquan Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1698247

981 views

Original Research

Published on 25 Nov 2025

Exploring the relationship of triglyceride to high-density lipoprotein cholesterol and the triglyceride-glucose index with white matter hyperintensities in individuals with type 2 diabetes: a cross-sectional analysis

in Translational and Clinical Endocrinology

Jun Pan
Juan Zheng
Hua Dong
Haili Zhang
Zhiwei Hu
Zhangchao Tang
Hanwen Xu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1639083

1,115 views

Review

Published on 17 Nov 2025

Microbiome−mediated crosstalk between T2DM and MASLD: a translational review focused on function

in Translational and Clinical Endocrinology

Menghui Jing
Yuanye Jiang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1677175

3,988 views
1 citation

Systematic Review

Published on 11 Nov 2025

Stress-induced hyperglycemia and mortality of non-diabetic patients with sepsis: a meta-analysis

in Translational and Clinical Endocrinology

Jiayang Huang
Junwei Li
Xiaowen Chen
Jiayu Gu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1688494

1,834 views

Review

Published on 05 Nov 2025

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

in Translational and Clinical Endocrinology

Mei Zhao
Danlin Chen
Xiumei Hu
Caiping Xie
Lianwei Xu
Fuhua Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684492

3,027 views
1 citation

Review

Published on 05 Nov 2025

Exploring the therapeutic potential of phytochemicals apigenin and ellagic acid in managing polycystic ovarian syndrome and its comorbidities: a comprehensive review

in Translational and Clinical Endocrinology

Acharya Balkrishna
Maneesha Rana
Shalini Mishra
Ritik Agrawal
Satyendra Kumar Rajput
Muralikrishnan Dhanasekaran
Mamta Rana
Vedpriya Arya
Ramith Ramu
Ashutosh Upadhayay

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1633377

3,223 views

Original Research

Published on 05 Nov 2025

Relationship between systemic immune-inflammation index and all-cause mortality in stages IIIB–IV epidermal growth factor receptor-mutated lung adenocarcinoma

in Translational and Clinical Endocrinology

Chi Zhang
Chao Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1698317

1,194 views
1 citation

Study Protocol

Published on 04 Nov 2025

Study protocol of a multicenter, randomized, non-inferiority, open-label study investigating the efficacy of a fixed-dose combination regimen of dapagliflozin/metformin versus co-administered dual therapy based on glycemic control, satisfaction and adherence in patients with newly diagnosed type 2 diabetes mellitus

in Translational and Clinical Endocrinology

Jiaxuan Wang
Ying Wei
Ping Shi
Ji Chen
Lingling Xu
Yinghong Kong
Jun Ye
Xueqin Wang
Juan Xu
Guang Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690339

2,921 views

Original Research

Published on 29 Oct 2025

From traditional metabolic markers to ensemble learning: comparative application of machine learning models for predicting NAFLD risk in adolescents

in Translational and Clinical Endocrinology

Chenming Zhang
Bin Niu
Rong Wang
Liaoyun Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1681686

2,076 views

515 articles

articles

Independent effects of exercise intensity on hepatic fat reduction in adults with metabolic dysfunction–associated steatotic liver disease: a randomized controlled trial protocol

Testosterone plus lifestyle therapy improves skeletal muscle glycolysis in older men with obesity and hypogonadism

The effectiveness of digital health interventions on anthropometric and healthy behaviour in women with polycystic ovarian syndrome: A Systematic Review with Meta-analysis

Correction: From traditional metabolic markers to ensemble learning: comparative application of machine learning models for predicting NAFLD risk in adolescents

Functional analysis from ex-vivo characterization of LDLR exon 13-15 duplication associated to Familial Hypercholesterolemia

Neutrophil percentage-to-albumin ratio as a novel hematologic biomarker for predicting arteriogenic erectile dysfunction

Whole-body vibration training on functional capacity, vascular function, and glycemic control in type 2 diabetes individuals with peripheral arterial disease: protocol for a randomized clinical trial

Remnant cholesterol: an independent, dose-dependent risk factor for hyperuricemia in a normolipidemic chinese population

Continuous auricular acupuncture and daytime intermittent electroacupuncture as a complementary therapeutic improve glycemic variability and stability under Continuous Glycemic Monitoring System in hospitalized diabetic patients

Residual cholesterol is independently associated with arteriogenic erectile dysfunction: results from a multi-institutional study

Research progress in precision medicine for type 2 diabetes based on the GLP-1

Research progress on multidimensional intervention strategies for hyperuricemia: Western medicine, Traditional Chinese Medicine, and emerging therapies

Morphological and functional alterations in type 2 diabetes pancreata assessed with MRI-based metrics and [18F]FP-(+)-DTBZ PET

Extracellular vesicle miR-425-5p promotes visceral fat reduction via DACT1 suppression in SGLT2i-treated diabetes

Risks of pelvic inflammatory disease and bacterial vaginosis in adenomyosis patients using levonorgestrel intrauterine device or oral norethindrone

Accurate screening of patients with diabetes based on physical examination: pancreas imaging features from chest CT and laboratory data

Exploring the relationship of triglyceride to high-density lipoprotein cholesterol and the triglyceride-glucose index with white matter hyperintensities in individuals with type 2 diabetes: a cross-sectional analysis

Microbiome−mediated crosstalk between T2DM and MASLD: a translational review focused on function

Stress-induced hyperglycemia and mortality of non-diabetic patients with sepsis: a meta-analysis

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

Exploring the therapeutic potential of phytochemicals apigenin and ellagic acid in managing polycystic ovarian syndrome and its comorbidities: a comprehensive review

Relationship between systemic immune-inflammation index and all-cause mortality in stages IIIB–IV epidermal growth factor receptor-mutated lung adenocarcinoma

From traditional metabolic markers to ensemble learning: comparative application of machine learning models for predicting NAFLD risk in adolescents