AUTHOR=Yan Xudong TITLE=Gastric bezoar: a simple and innovative lithotripsy method—a case report and review of the literature JOURNAL=Frontiers in Gastroenterology VOLUME=Volume 4 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/gastroenterology/articles/10.3389/fgstr.2025.1527031 DOI=10.3389/fgstr.2025.1527031 ISSN=2813-1169 ABSTRACT=Gastrointestinal bezoars result from the ingestion of indigestible materials and are classified by their consistency. This material is commonly located in the stomach. Human bezoars may be formed by non-digestible plant fibers (phytobezoars), persimmons (diospyrobezoar), hair (trichobezoar), long-acting medications (pharmacobezoar), milk and mucus components (lactobezoar), or other various substances. This condition may be asymptomatic, or it may cause symptoms such as stomachache, ulcers, bleeding, perforation, gastric outlet obstruction, and mechanical intestinal obstruction. We herein report a simple and innovative lithotripsy method using Zebra Guidewire, and review the pathogenesis, clinical manifestations, and treatment of bezoars.