AUTHOR=Xiao Han , Kang Sona 

TITLE=The Role of the Gut Microbiome in Energy Balance With a Focus on the Gut-Adipose Tissue Axis

JOURNAL=Frontiers in Genetics

VOLUME=Volume 11 - 2020

YEAR=2020

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2020.00297

DOI=10.3389/fgene.2020.00297

ISSN=1664-8021

ABSTRACT=Obesity is a complex disease attributable to many factors including genetics and environmental influences. Growing evidence suggests that gut microbiota is a major contributing factor to the pathogenesis of obesity and other metabolic disorders. This article reviews the current understanding of the role of gut microbiota in the regulation of energy balance and the development of obesity, and how the microbiota communicates with host tissues, in particular adipose tissue.