AUTHOR=Dekomah Simon Dontoro , Bi Zhenzhen , Dormatey Richard , Wang Yihao , Haider Fasih Ullah , Sun Chao , Yao Panfeng , Bai Jiangping 

TITLE=The role of CDPKs in plant development, nutrient and stress signaling

JOURNAL=Frontiers in Genetics

VOLUME=Volume 13 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.996203

DOI=10.3389/fgene.2022.996203

ISSN=1664-8021

ABSTRACT=The second messenger calcium (Ca2+) is a ubiquitous intracellular signaling molecule found in eukaryotic cells. In plants, the multigene family of calcium-dependent protein kinases (CDPKs) plays an important regulatory role in plant growth and development and stress tolerance. CDPKs sense intracellular Ca2+ concentration changes and convert them into phosphorylation events that initiate downstream signaling processes. Several functional and expression studies of different CDPKs and their encoding genes confirmed their multi-functional role for stress. Here we review the signaling transduction mechanism and functional roles of CDPKs. This review provided details on; secondary metabolites regulation, nutrient uptake, regulation of flower development, hormonal regulation, and biotic and abiotic stress responses.