AUTHOR=Ke Juan , Chen Changyi , Fei Junwen , Luo Ke , Cheng Yu , Yu Huimin , Cheng Chao , Yan Yiqing , Zhang Xiaoran , Liang Shuang , Sun Hao , Bai Chunyan , Sun Boxing 

TITLE=Genome-wide analysis of genetic loci and candidate genes related to teat number traits in Dongliao black pigs

JOURNAL=Frontiers in Genetics

VOLUME=Volume 16 - 2025

YEAR=2025

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2025.1593395

DOI=10.3389/fgene.2025.1593395

ISSN=1664-8021

ABSTRACT=This study investigated the genetic basis of teat number variation in Dongliao black pigs. A total of 765 pigs were genotyped using the Porcine 50K SNP chip, and their teat numbers were recorded. Heritability estimates for total teat number (TTN) and teat pair number (TPN) were 0.091 and 0.097, respectively. Genome-wide association studies identified 74 significant SNPs for TTN and 105 for TPN. Nine candidate genes related to the teat number were identified: CSNK1G1, PLEKHM2, CABLES1, SLC25A21, RYR3, PIGH, GUCY1A1, RAPGEF2, and TRPC4AP. These findings provide insights into the genetic architecture of teat number variation in Dongliao black pigs.