Frontiers in Genetics

Original Research

Published on 26 Mar 2025

Multi-omics pan-cancer analysis reveals the diagnostic and prognostic value of C8orf76, with experimental validation of its impact on lung adenocarcinoma cell proliferation

in Cancer Genetics and Oncogenomics

Xiaohong Zhong
Zhiyong Zhang
Rongjing Gao
Shiqi Ren
Shifang Li
Miao Zhang
Jie Fang
Yanjiao Hou

Frontiers in Genetics

doi 10.3389/fgene.2025.1524422

841 views

Original Research

Published on 26 Mar 2025

A comprehensive analysis of microRNA alteration in an ApoE(−/−) mice model of white adipose tissue injury induced by chronic intermittent hypoxia

in RNA

Jinjie Zhang
Yaopeng Guo
Meilin Ji
Shu Lin
Dexin Liu
Qingshi Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1474223

751 views

Original Research

Published on 25 Mar 2025

Blood toxicogenomics reveals potential biomarkers for management of idiosyncratic drug-induced liver injury

in Toxicogenomics

Rachel J. Church
Benedict Anchang
Brian D. Bennett
Pierre R. Bushel
Paul B. Watkins

Frontiers in Genetics

doi 10.3389/fgene.2025.1524433

918 views

Original Research

Published on 25 Mar 2025

Karyotype and genome size analyses for two spiders of the lycosidae family

in Molecular Cytogenetics

Yuxuan Zhang
Mengying Zhang
Liang Leng
Ya Wu
Hanting Yang
Liangting Wang
Baimei Liu
Shuai Yang
Zizhong Yang
Shilin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1544087

730 views

Original Research

Published on 25 Mar 2025

Genetic analysis reveals the shared genetic architecture between breast cancer and atrial fibrillation

in Applied Genetic Epidemiology

Yang Yang
Jiayi Chen
XiaoHua Zhao
Fuhong Gong
Ruimin Liu
Jingge Miao
Mengping Lin
Fei Ge
Wenlin Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1450259

1,196 views

Original Research

Published on 25 Mar 2025

Novel variations in the PLOD1, COL1A1, COL5A2 and COL4A1 genes related to keratoconus

in Genetics of Common and Rare Diseases

Qinghong Lin
Xuejun Wang
Xiaoliao Peng
Tian Han
Ling Sun
Xiaoyu Zhang
Xingtao Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1497915

641 views

Original Research

Published on 24 Mar 2025

Multi-trait phenotypic modeling through factor analysis and bayesian network learning to develop latent reproductive, body conformational, and carcass-associated traits in admixed beef heifers

in Livestock Genomics

Muhammad Anas
Bin Zhao
Haipeng Yu
Carl R. Dahlen
Kendall C. Swanson
Kris A. Ringwall
Lauren L. Hulsman Hanna

Frontiers in Genetics

doi 10.3389/fgene.2025.1551967

823 views

Review

Published on 24 Mar 2025

Genetic diversity, reproductive performance, and genetic enhancement strategies in Huang-Huai goats

in Livestock Genomics

Kai Quan
Huibin Shi
Caihong Wei
Jun Li
Kun Liu
Huihua Wang
Wei Sun
Haoyuan Han

Frontiers in Genetics

doi 10.3389/fgene.2025.1549051

690 views

Original Research

Published on 24 Mar 2025

Construction of a risk model associated with tryptophan metabolism and identification of related molecular subtypes in laryngeal squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Feng Liu
Yanchao Qin
Wei Luo
XianHui Ruan
Lifang Lu
Bowei Feng
Jianfei Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1530334

913 views

Brief Research Report

Published on 24 Mar 2025

Genetic genealogy of Y-chromosome in the Zhetiru tribe of the Kazakh population from Kazakhstan

in Evolutionary and Population Genetics

Aigul Zhunussova
Saltanat Tayshanova
Alizhan Bukayev
Ayagoz Bukayeva
Baglan Aidarov
Radik Temirgaliev
Zhaxylyk Sabitov
Maxat Zhabagin

Frontiers in Genetics

doi 10.3389/fgene.2025.1516130

2,024 views

Original Research

Published on 21 Mar 2025

Assessment of physician preparedness for implementation of pathology-supported genetic testing: solution-driven post-COVID-19 survey

in Human and Medical Genomics

Elouise E. Kroon
Yolandi Swart
Chantelle J. Scott
Denise Scholtz
Daniel W. Olivier
Kelebogile E. Moremi
Chantelle Venter
Maxine Waters
Sunday O. Oladejo
Craig J. Kinnear

Frontiers in Genetics

doi 10.3389/fgene.2025.1543056

879 views

Original Research

Published on 21 Mar 2025

A semi-supervised weighted SPCA- and convolution KAN-based model for drug response prediction

in Computational Genomics

Rui Miao
Bing-Jie Zhong
Xin-Yue Mei
Xin Dong
Yang-Dong Ou
Yong Liang
Hao-Yang Yu
Ying Wang
Zi-Han Dong

Frontiers in Genetics

doi 10.3389/fgene.2025.1532651

659 views

Original Research

Published on 21 Mar 2025

Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis

in Computational Genomics

Xiu-De Qin
Yue-Rong Li
Qian Cai
Jia-Ye Liu
Zhao-Hui Dang
Li-Ling Li
Jia-Wei Min
Shao-Hua Qi
Fan Bu

Frontiers in Genetics

doi 10.3389/fgene.2025.1479270

938 views

Original Research

Published on 21 Mar 2025

Cancer classification in high dimensional microarray gene expressions by feature selection using eagle prey optimization

in Computational Genomics

Swetha Dhamercherla
Damodar Reddy Edla
Suresh Dara

Frontiers in Genetics

doi 10.3389/fgene.2025.1528810

528 views

Original Research

Published on 20 Mar 2025

Identified five variants in CFTR gene that alter RNA splicing by minigene assay

in Genetics of Common and Rare Diseases

Bingying Zhang
Yiyin Zhang
Yan Zhang
Xuyan Liu
Ran Zhang
Zhi Wang
Fengjiao Pan
Ning Xu
Leping Shao

Frontiers in Genetics

doi 10.3389/fgene.2025.1543623

840 views

Original Research

Published on 20 Mar 2025

MDNN-DTA: a multimodal deep neural network for drug-target affinity prediction

in Computational Genomics

Xu Gao
Mengfan Yan
Chengwei Zhang
Gang Wu
Jiandong Shang
Congxiang Zhang
Kecheng Yang

Frontiers in Genetics

doi 10.3389/fgene.2025.1527300

769 views