Frontiers in Genetics

Perspective

Published on 08 Oct 2025

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

in ELSI in Science and Genetics

Zachary T. Sentell
Ma’n H. Zawati

Frontiers in Genetics

doi 10.3389/fgene.2025.1685854

2,408 views

Review

Published on 08 Oct 2025

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

in Cancer Genetics and Oncogenomics

Min Xu
Xialin Zhang
Xinlin Yu
Cheng Ma
Xinwei Li
Gang Chen
Gang Yuan
Sheng Lin
Ran Cui

Frontiers in Genetics

doi 10.3389/fgene.2025.1666561

2,454 views
1 citation

Original Research

Published on 08 Oct 2025

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

in Cancer Genetics and Oncogenomics

Chencheng Zhang
Weiwei Xu
Xudong Chen
Xingdan Wang
Xiaopeng Cui
Wenjing Zhao

Frontiers in Genetics

doi 10.3389/fgene.2025.1600883

2,753 views

Editorial

Published on 08 Oct 2025

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

in ELSI in Science and Genetics

Michel Satya Naslavsky
Tayyaba Jiwani
Ernesto Schwartz-Marin

Frontiers in Genetics

doi 10.3389/fgene.2025.1703507

1,814 views

Brief Research Report

Published on 08 Oct 2025

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

in Genetics of Common and Rare Diseases

Anna Hu
Jun Liang
Hongbo Liu
Jinghui Jiang
Fujing Xie
Xin Zhou
Xiaojia Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1687266

1,807 views

Review

Published on 08 Oct 2025

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

in RNA

Ramkumar Muthu
Rajkumar Manickam
Rajkumar Thamarai
Sivabalan Sivasamy
Karthikeyan Mahendran
Rajkumar Prabhakaran

Frontiers in Genetics

doi 10.3389/fgene.2025.1668618

4,288 views
1 citation

Original Research

Published on 08 Oct 2025

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

in RNA

Haixia Huang
Ling Sun
Fan Jia
Yong Tan
Yahong Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1658812

2,320 views

Correction

Published on 07 Oct 2025

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

in Cancer Genetics and Oncogenomics

Xiaoping Yang
Zuohui Yuan
Lingzhu Gou
Long Cheng
Zirui Wang
Pingfan Wu
Xiaochun Wang
Xueni Ma
Tiantian Ma
Yi Yu

Frontiers in Genetics

doi 10.3389/fgene.2025.1684479

1,422 views

Correction

Published on 07 Oct 2025

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

in Computational Genomics

Ning Zhang
Ye Zhang
Rui-Fei Yang
Min Tan
Hai-Qing Chu
Abdur Rehman
Lu-Yu Yang
Ya-Yu Li
Fahad M. Alshabrmi
Xin Zhou

Frontiers in Genetics

doi 10.3389/fgene.2025.1701926

1,374 views

Original Research

Published on 07 Oct 2025

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

in Immunogenetics

Lin Wang
Aiyan Ren
Yuanyuan He
Lu Wang
Sixi Wang
Xin Xie
Mei Tan
Yan Chen
Pei Huang
Zuochen Du

Frontiers in Genetics

doi 10.3389/fgene.2025.1641956

3,530 views
1 citation

Original Research

Published on 07 Oct 2025

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

in Computational Genomics

Guirong Yi
Peng Zhou
Qinxu Yang
Maosheng Zhao
Qiaoqiao Yang
Shensong Li
Chenpo Dang

Frontiers in Genetics

doi 10.3389/fgene.2025.1609915

2,655 views

Review

Published on 06 Oct 2025

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

in Genomics of Plants and the Phytoecosystem

Renu Sharma
Satish Kumar
C. N Mishra
O. P. Ahlawat
Ratan Tiwari

Frontiers in Genetics

doi 10.3389/fgene.2025.1687301

2,733 views

Review

Published on 03 Oct 2025

The roles of serine protease inhibitors in dermatoses

in Applied Genetic Epidemiology

Zhenzhen Xiao
Yue Kang
Yunqian Zhuo
Rui Li
Yingjian Tan

Frontiers in Genetics

doi 10.3389/fgene.2025.1624512

4,307 views

Policy and Practice Reviews

Published on 03 Oct 2025

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

in ELSI in Science and Genetics

Aaliah Charles
Zané Lombard
Nadia Carstens
Zandisiwe Goliath
Aimé Lumaka
Prince Makay
Nadja Louw
Robyn Kerr
Daniesha Govender
Amanda Krause

Frontiers in Genetics

doi 10.3389/fgene.2025.1611047

3,335 views

Original Research

Published on 03 Oct 2025

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

in Computational Genomics

Jiawei Wang
Shaojie Qiao
Dongsheng Xiang
Yangcheng Liao
Chao Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1650244

2,479 views

Original Research

Published on 03 Oct 2025

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

in Behavioral and Psychiatric Genetics

Michael Fritz
Karlheinz Holzmann
Silvia Castany
Heidrun Haas
Christian Montag
David Engblom
Judith Streb
Manuela Dudeck

Frontiers in Genetics

doi 10.3389/fgene.2025.1653768

4,486 views
1 citation

Review

Published on 02 Oct 2025

Recent advances of DNA methylation in osteonecrosis of the femoral head

in Epigenomics and Epigenetics

Tingting Zhou
Huan Liu
Huayan Li
Yan Zhang
Xiaoming Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1526852

4,166 views

Original Research

Published on 02 Oct 2025

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)

in Livestock Genomics

Xiang Ding
Zukai Liu
Linsen Ou
Zhihui Wang
Qian Xu
Runlang Su

Frontiers in Genetics

doi 10.3389/fgene.2025.1665548

2,851 views

Original Research

Published on 02 Oct 2025

Analyses of haplotypes of TLR2 and TLR3 genes for COVID-19 prognosis in a cohort of professionals who worked in the first pandemic wave in Belém-PA, Brazil

in Computational Genomics

Marcos Jessé Abrahão Silva
Luiza Raquel Tapajós Figueira
Daniele Melo Sardinha
Eliete Costa da Cruz
Natasha Cristina Oliveira Andrade
Sebastião Kauã De Sousa Bispo
Thiago Augusto Ferreira Dos Anjos
Everaldina Cordeiro Dos Santos
Ana Judith Pires Garcia
Luana Nepomuceno Gondim Costa Lima

Frontiers in Genetics

doi 10.3389/fgene.2025.1659269

1,686 views
1 citation

Mini Review

Published on 01 Oct 2025

Recent progress on DNA methylation in psoriasis

in RNA

Zhaoping Lin
Xiaoting Wu
Xuqin Hong
Dongying Luo
Hui Li
Fei Ma
Cong Huang
Bo Yu
Jing Gao
Changbing Shen

Frontiers in Genetics

doi 10.3389/fgene.2025.1681666

4,077 views

Original Research

Published on 01 Oct 2025

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

in Cancer Genetics and Oncogenomics

Mingzhi Cai
Xinyang Nie
Fenglin Cai
Xiuding Yang
Weilin Sun
Rupeng Zhang
Han Liang
Yonglin Yang
Li Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1653700

2,678 views
1 citation

Original Research

Published on 01 Oct 2025

Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race

in Livestock Genomics

Shikun Ma
Wanlu Ren
Zexu Li
Luling Li
Ran Wang
Yi Su
Qiuping Huang
Shan Dehaxi
Jianwen Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1676558

3,104 views
2 citations

Original Research

Published on 01 Oct 2025

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

in Epigenomics and Epigenetics

Maxim N. Shokhirev
Adiv A. Johnson

Frontiers in Genetics

doi 10.3389/fgene.2025.1637186

4,467 views

Data Report

Published on 01 Oct 2025

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach

in Computational Genomics

Friederike Reuss
Tilman Schell
Haruhiko Isawa
Shinji Kasai
Sven Klimpel
Ruth Müller
Markus Pfenninger
Judith Kochmann

Frontiers in Genetics

doi 10.3389/fgene.2025.1667262

2,688 views

16,577 articles

articles

Ethical, legal, and policy dimensions and contentions for reanalysis and reinterpretation of clinical genetic testing results

Epigenetic and metabolic reprogramming via nanotechnology: a synergistic approach to cancer vaccination in lung tumors

Pain - related methylation driver genes affect the prognosis of pancreatic cancer patients by altering immune function and perineural infiltration

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south

A novel splicing variant in NBAS identified by minigene assay causes infantile liver failure syndrome type 2

NanoMarine therapeutics: a new wave in drug delivery from oceanic bioresources targeting colon cancer via miRNA modulation

Modulation of the lncRNA TCONS_00265853-miR-421-5p-CLOCK axis by Ziyin Buyang Formula in polycystic ovarian syndrome with circadian rhythm disruption: an integrated bioinformatics and experimental approach

Correction: FEZF1-AS1 drives autophagy-mediated progression of colon cancer and reduces chemosensitivity through inhabiting the PI3K/AKT/mTOR signaling pathway

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

A novel de novo IL2RG nonsense mutation in a pediatric patient with X-linked severe combined immunodeficiency

Identification of shared diagnostic genes between osteoporosis and Crohn’s disease through integrated transcriptomic analysis and machine learning

Harnessing multi-omics approaches to combat Karnal bunt of wheat: a review of advances and future prospects

The roles of serine protease inhibitors in dermatoses

A training program to extend the reach of the deciphering developmental disorders in Africa (DDD-Africa) study

HFTC: a hierarchical fungal taxonomic classification model for ITS sequences using low-dimensional embedding features

Sex-specific gene expression and weighted co-expression network analysis suggest distinct sex-specific molecular signatures in acutely suicidal MDD-patients without somatic comorbidities

Recent advances of DNA methylation in osteonecrosis of the femoral head

Time-series transcriptomics and alternative splicing analysis of embryonic development of the asian honeybee (Apis cerana)

Analyses of haplotypes of TLR2 and TLR3 genes for COVID-19 prognosis in a cohort of professionals who worked in the first pandemic wave in Belém-PA, Brazil

Recent progress on DNA methylation in psoriasis

Identification and validation of calcium signaling pathway-related biomarkers in T1 and T2 lymph node metastatic gastric cancer

Comparative analysis of miRNA expression in Yili horses pre- and post-5000-m race

Using buccal methylomic data to create explainable aging clocks as well as classifiers and regressors for lifestyle and demographic factors

Annotated genome of Aedes japonicus japonicus using a hybrid-assembly approach