AUTHOR=Kimmel Mary , Thippeswamy Harish , Kamperman Astrid , Madhuri H. N. , Putnam Karen , Schiller Crystal , Weinel Katie , Rackers Hannah , Gilden Janneke , Bergink Veerle , Meltzer-Brody Samantha , Chandra Prabha TITLE=Cross-continental collaboration for understanding postpartum major depression with psychotic features JOURNAL=Frontiers in Global Women's Health VOLUME=Volume 3 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/global-womens-health/articles/10.3389/fgwh.2022.996501 DOI=10.3389/fgwh.2022.996501 ISSN=2673-5059 ABSTRACT=Purpose: Assess postpartum depression and psychotic symptoms from three continents. Methods: Compare numbers of women with depression and psychotic symptoms, mania with or without psychotic features, or transient non-affective psychosis and medication choice. Results: The prevalence of postpartum depression and psychosis and treatment choice differed at each site. Conclusions: Best treatment for postpartum depression with psychotic features has not been established yet. Cross-continental collaboration with similar assessments holds promise to develop best practices for these high risk mother-infant dyads.