AUTHOR=Negese Ketemaw , Belachew Dereje Zeleke TITLE=Maternal complications and associated factors among mothers who underwent a cesarean section at Gebretsadik Shewa general hospital: an institution based cross-sectional study JOURNAL=Frontiers in Global Women's Health VOLUME=Volume 4 - 2023 YEAR=2023 URL=https://www.frontiersin.org/journals/global-womens-health/articles/10.3389/fgwh.2023.1091863 DOI=10.3389/fgwh.2023.1091863 ISSN=2673-5059 ABSTRACT=Abstract Introduction: Cesarean section has played a major role in lowering maternal morbidity and mortality rates, but it is a major concern in developing countries. This study aims to assess magnitude of maternal complication and its associated factors among women underwent cesarean section at Gebretsadik shewa general hospital, southwest Ethiopia. Method: A hospital-based cross-sectional study was conducted in Gebretsadik shewa general hospital. Data were extracted from 382 mothers’ medical charts, retrieved from labor and operations theatre log book registry using systematic random sampling technique. The extracted data was coded and entered into Epi Data version 3.0, and exported to Statistical Package for Social Sciences (SPSS) version 20 for analysis. Logistic regression analysis was conducted and significance and strength association was determined considering AOR with a 95% confidence level. Result: A total of 382 mothers’ charts were reviewed; however, 368 charts were eligible for data entry. Age of the participants ranges between 16 and 42 years with mean and standard deviation of 26.1+4.8 years. Maternal complication rate was 30.4% [95% CI: 25.8- 35.1]. Surgical site infection (10.3%), anemia (6.5%) and intraoperative bleeding (4.6%). Multivariable logistic regression analysis showed that no antenatal care follow up, medical illness during pregnancy, emergency cesarean section and not received prophylactic antibiotic were statistically associated with maternal complication. Conclusion: The incidence of maternal complication following cesarean delivery was unduly high. Community based education should be further strengthened about antenatal care follow up and its importance for favorable maternal and fetal outcome. Key words: Maternal complication, caesarean section, Gebretsadik shewa general hospital.