AUTHOR=Gerete Tamirat Beyene , Demissie Asresash , Sewmehone Enatfenta , Gezimu Wubishet TITLE=Women's knowledge and attitudes toward female genital mutilation and associated factors in Diguna Fango, a rural district in southern Ethiopia: a community-based mixed study JOURNAL=Frontiers in Global Women's Health VOLUME=Volume 6 - 2025 YEAR=2025 URL=https://www.frontiersin.org/journals/global-womens-health/articles/10.3389/fgwh.2025.1516925 DOI=10.3389/fgwh.2025.1516925 ISSN=2673-5059 ABSTRACT=BackgroundFemale genital mutilation (FGM) is a widely practiced custom in Ethiopia. The women's knowledge and attitudes toward it and influencing factors have not been explored in Ethiopia, particularly in the rural districts. Hence, this study assessed women's knowledge and attitudes toward female genital mutilation and associated factors in Diguna Fango, a rural district in southern Ethiopia.MethodsThis study adopted a community-based cross-sectional study design using a sequential mixed-method explanatory approach. It was conducted from May 20, 2023, to June 30, 2023, among 821 participants selected using a multistage sampling technique. The quantitative data were collected using a structured interviewer-administered questionnaire. A key informant interview was conducted to collect the qualitative data. A binary logistic regression analysis was conducted to identify factors associated with the outcome variables. A p-value <0.05 at a 95% CI was used to declare statistical significance.ResultsOf the 821 participants included in the study, 53.2% had good knowledge and 46% had an unfavorable attitudes towards female genital mutilation, respectively. Monthly income (AOR = 1.61; 95% CI: 1.39–2.95) and partners’ educational status (AOR = 2.17; 95% CI: 1.37–4.89) were significantly associated with knowledge, whereas being a government employee (AOR = 2.12; 95% CI = 1.45–3.11) and private employee (AOR = 3.99; 95% CI = 1.63–6.77), having student partners (AOR = 2.64; 95% CI = 1.40–4.95), circumcision history (AOR = 2.58; 95% CI = 1.41–4.71), and knowledge (AOR = 1.48; 95% CI = 1.11–1.98) were shown to be associated with attitude towards female genital mutilation. Moreover, sociocultural drivers, awareness of adverse health effects, religious attributes, and sexuality concerns were explored as attributes of knowledge and attitudes toward female genital mutilation/cutting.ConclusionCompared to previous similar local and global findings, lower levels of knowledge and higher levels of support for female genital mutilation were observed in the area. Sociocultural, religious, and sexual concerns influence knowledge and attitudes toward female genital mutilation. Therefore, the concerned bodies need to mobilize the community and work closely with the health development armies and religious institutions to boost women's knowledge and change favorable attitudes towards FGM/C.