AUTHOR=Lu Yao , Yuan Ziyang , Chen Jiaping , Wang Zeyi , Liu Zhandong , Wu Yanjue , Zhan Donglin , Zhao Qingbao , Pei Mofei , Xie Minhao TITLE=A New Tool for Rapid Assessment of Acute Exercise-Induced Fatigue JOURNAL=Frontiers in Human Neuroscience VOLUME=Volume 16 - 2022 YEAR=2022 URL=https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2022.856432 DOI=10.3389/fnhum.2022.856432 ISSN=1662-5161 ABSTRACT=Background: There are limited sensitive evaluation methods to distinguish people’s symptoms of peripheral fatigue and central fatigue simultaneously, the purpose of this study is to identify and evaluate them after acute exercise with a simple and practical scale. Methods: The initial scale was built through a literature review, experts and athlete population survey, and a small sample pre-survey. Randomly selected 1506 students were evaluated with the initial scale after exercise. Subjective fatigue self-assessments (SFSA) were completed at the same time. Results: The Acute Exercise-Induced Fatigue Scale (AEIFS) was determined after performing a factor analysis. In the exploratory factor analysis, the cumulative variance contribution rate was 65.464%. The factor loadings of total 8 questions were 0.661~0.816. In the confirmatory factor analysis, χ2 /df = 2.529, GFI = 0.985, AGFI = 0.967, NFI = 0.982, RFI = 0.970, IFI = 0.989, CFI = 0.989, and RMSEA = 0.048. The Cronbach's alpha coefficient for the scale was 0.872, 0.833 for peripheral fatigue, and 0.818 for central fatigue. The intra-class correlation coefficient for the scale was 0.536, and the intra-class correlation coefficients for peripheral fatigue and central fatigue were 0.421 and 0.548. The correlation coefficient between the total score of the AEIFS and the SFSA score was 0.592 (p<0.01). Conclusions: Our results demonstrate that the AEIFS can distinguish peripheral fatigue and central fatigue, and also reflect their correlation. This scale can be a useful evaluation tool not only for fatigue after acute exercise but also in guiding reasonable exercise, choosing objective testing indicators, and preventing sport injuries resulting from acute exercise-induced fatigue.