AUTHOR=Xu Shan-Shan , Zhu Shi-Guo , Yuan Cheng-Xiang , Zeng Guo-Ling , Li Xiao-Tian , Liu Rong-Pei , Huang Shi-Shi , Zhang Xiong , Wang Jian-Yong 

TITLE=Case report: Levodopa challenge test is important in identifying dopamine-induced freezing of gait in patient with Parkinson’s disease

JOURNAL=Frontiers in Human Neuroscience

VOLUME=Volume 18 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2024.1464152

DOI=10.3389/fnhum.2024.1464152

ISSN=1662-5161

ABSTRACT=Introduction: Freezing of gait (FOG) is a disabling and heterogeneous symptom in patients with Parkinson’s disease (PD). Among them, dopamine-induced FOG is rare and difficult to identify. The treatment of dopamine-induced FOG is complex.
Case presentation: We herein presented a case of PD patient who complicated with refractory FOG. It was identified as dopamine-induced FOG during levodopa challenge test. Her symptoms were alleviated after we reduced the total equivalent dosage of levodopa.
Conclusion: Our report emphasizes the importance of levodopa challenge test in identifying different types of FOG, which is very important for further adjusting treatment.